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Conference Paper: Association between gout and depression: The United States National Health Nutrition and Examination Survey 2007-2016

TitleAssociation between gout and depression: The United States National Health Nutrition and Examination Survey 2007-2016
Authors
Issue Date2020
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org/
Citation
The 25th Annual Medical Research Conference, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, 18 January 2020. In Hong Kong Medical Journal, 2020, v. 26 n. 1, Suppl. 1, p. 31, abstract no. 49 How to Cite?
AbstractIntroduction: Acute gout is painful and can lead to anxiety and depression. Whether gout leads to chronic depression is unclear. Methods: A total of 25 016 adult participants who responded to the 9-item Patient Health Questionnaire in the United States NHANES (National Health Nutrition and Examination Survey) 2007-2016 were included in this analysis. The diagnosis of gout was based on self-reporting. Results were analysed using SPSS complex sample module version 25. Logistic regression was used to study the association between gout and depression. Odds ratio (OR) and 95% confidence interval (CI) were estimated. Results: Although there was increased prevalence of depression among participants with gout (without gout vs gout: 7.9% [7.4%-8.5%] vs 9.8% [7.8%-12.4%]; P=0.003), gout was not independently associated with depression in both univariate (OR=1.27, 95% CI=0.99-1.63) and multivariate analysis (OR=1.15, 95% CI=0.84-1.56). Multivariate analysis showed that female sex (OR=1.75, 95% CI=1.51-2.04), education (college graduate vs <9th grade: OR=0.47 [95% CI=0.34-0.64]; college/associate degree vs <9th grade: 0.71 [0.56-0.91]; high school vs <9th grade: 0.74 [0.59-0.92]; 9-11th grade vs <9th grade: 0.94 [0.77-1.14]), alcohol consumption (OR=1.18, 95% CI=1.03-1.35), body mass index (OR=1.02, 95% CI=1.01-1.03), as well as the co-morbidities of gout, including diabetes (OR=1.23, 95% CI=1.03-1.35), hypertension (OR=1.52, 95% CI=1.27-1.82), and coronary heart disease (OR=1.63, 95% CI=1.12-2.38) were associated with depression. Conclusions: Gout is not independently associated with depression. However, physicians should still watch out for depression in patients with gout.
Persistent Identifierhttp://hdl.handle.net/10722/281727
ISSN
2019 Impact Factor: 1.679
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorTsoi, MF-
dc.contributor.authorCheung, BMY-
dc.contributor.authorLau, WCS-
dc.contributor.authorCheung, TT-
dc.date.accessioned2020-03-22T04:18:48Z-
dc.date.available2020-03-22T04:18:48Z-
dc.date.issued2020-
dc.identifier.citationThe 25th Annual Medical Research Conference, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, 18 January 2020. In Hong Kong Medical Journal, 2020, v. 26 n. 1, Suppl. 1, p. 31, abstract no. 49-
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/281727-
dc.description.abstractIntroduction: Acute gout is painful and can lead to anxiety and depression. Whether gout leads to chronic depression is unclear. Methods: A total of 25 016 adult participants who responded to the 9-item Patient Health Questionnaire in the United States NHANES (National Health Nutrition and Examination Survey) 2007-2016 were included in this analysis. The diagnosis of gout was based on self-reporting. Results were analysed using SPSS complex sample module version 25. Logistic regression was used to study the association between gout and depression. Odds ratio (OR) and 95% confidence interval (CI) were estimated. Results: Although there was increased prevalence of depression among participants with gout (without gout vs gout: 7.9% [7.4%-8.5%] vs 9.8% [7.8%-12.4%]; P=0.003), gout was not independently associated with depression in both univariate (OR=1.27, 95% CI=0.99-1.63) and multivariate analysis (OR=1.15, 95% CI=0.84-1.56). Multivariate analysis showed that female sex (OR=1.75, 95% CI=1.51-2.04), education (college graduate vs <9th grade: OR=0.47 [95% CI=0.34-0.64]; college/associate degree vs <9th grade: 0.71 [0.56-0.91]; high school vs <9th grade: 0.74 [0.59-0.92]; 9-11th grade vs <9th grade: 0.94 [0.77-1.14]), alcohol consumption (OR=1.18, 95% CI=1.03-1.35), body mass index (OR=1.02, 95% CI=1.01-1.03), as well as the co-morbidities of gout, including diabetes (OR=1.23, 95% CI=1.03-1.35), hypertension (OR=1.52, 95% CI=1.27-1.82), and coronary heart disease (OR=1.63, 95% CI=1.12-2.38) were associated with depression. Conclusions: Gout is not independently associated with depression. However, physicians should still watch out for depression in patients with gout.-
dc.languageeng-
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org/-
dc.relation.ispartofHong Kong Medical Journal-
dc.relation.ispartof25th Medical Research Conference-
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.-
dc.titleAssociation between gout and depression: The United States National Health Nutrition and Examination Survey 2007-2016-
dc.typeConference_Paper-
dc.identifier.emailTsoi, MF: smftsoi@hku.hk-
dc.identifier.emailCheung, BMY: mycheung@hkucc.hku.hk-
dc.identifier.emailLau, WCS: cslau@hku.hk-
dc.identifier.emailCheung, TT: tcheungt@hku.hk-
dc.identifier.authorityCheung, BMY=rp01321-
dc.identifier.authorityLau, WCS=rp01348-
dc.identifier.authorityCheung, TT=rp01682-
dc.identifier.hkuros309415-
dc.identifier.volume26-
dc.identifier.issue1, Suppl. 1-
dc.identifier.spage31, abstract no. 49-
dc.identifier.epage31, abstract no. 49-
dc.publisher.placeHong Kong-

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