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Article: Systemic Lupus Erythematosus in a Patient with Ulcerative Colitis: Co-Existing or Drug-Induced?
Title | Systemic Lupus Erythematosus in a Patient with Ulcerative Colitis: Co-Existing or Drug-Induced? |
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Authors | |
Keywords | Systemic Lupus Erythematosus Ulcerative Colitis Inflammatory Bowel Disease Drug-Induced |
Issue Date | 2019 |
Publisher | WorldScientificOpen Journals. The Journal's web site is located at https://www.worldscientific.com/worldscinet/jcri |
Citation | Journal of Clinical Rheumatology and Immunology, 2019, v. 19 n. 2, p. 67-69 How to Cite? |
Abstract | We report a 49-year-old lady with ulcerative colitis (UC) who subsequently developed systemic lupus erythematosus (SLE) ten years later. By reviewing the drug history and serum autoimmune panel, we hypothesize that systemic lupus erythematosus may occur in a patient with a history of inflammatory bowel disease as a coexisting disease, or triggered by drugs used in inflammatory bowel disease, such as disease-modifying anti-rheumatic drugs (DMARDs). This case raises the discussion that patients with Inflammatory bowel disease (IBD) may have a genetic predisposition for developing other autoimmune diseases, and explores the possibility of drugs used in the treatment of IBD as a trigger for SLE development. Being able to differentiate the two has important implications in management and prognosis. |
Persistent Identifier | http://hdl.handle.net/10722/279460 |
ISSN |
DC Field | Value | Language |
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dc.contributor.author | Sun, FF | - |
dc.contributor.author | Chan, NL | - |
dc.contributor.author | Chan, TC | - |
dc.contributor.author | Leung, KL | - |
dc.contributor.author | Siu, YWA | - |
dc.contributor.author | Sui, CH | - |
dc.contributor.author | Yu, CL | - |
dc.contributor.author | Chung, HY | - |
dc.date.accessioned | 2019-11-01T07:17:47Z | - |
dc.date.available | 2019-11-01T07:17:47Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Journal of Clinical Rheumatology and Immunology, 2019, v. 19 n. 2, p. 67-69 | - |
dc.identifier.issn | 2661-3417 | - |
dc.identifier.uri | http://hdl.handle.net/10722/279460 | - |
dc.description.abstract | We report a 49-year-old lady with ulcerative colitis (UC) who subsequently developed systemic lupus erythematosus (SLE) ten years later. By reviewing the drug history and serum autoimmune panel, we hypothesize that systemic lupus erythematosus may occur in a patient with a history of inflammatory bowel disease as a coexisting disease, or triggered by drugs used in inflammatory bowel disease, such as disease-modifying anti-rheumatic drugs (DMARDs). This case raises the discussion that patients with Inflammatory bowel disease (IBD) may have a genetic predisposition for developing other autoimmune diseases, and explores the possibility of drugs used in the treatment of IBD as a trigger for SLE development. Being able to differentiate the two has important implications in management and prognosis. | - |
dc.language | eng | - |
dc.publisher | WorldScientificOpen Journals. The Journal's web site is located at https://www.worldscientific.com/worldscinet/jcri | - |
dc.relation.ispartof | Journal of Clinical Rheumatology and Immunology | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Systemic Lupus Erythematosus | - |
dc.subject | Ulcerative Colitis | - |
dc.subject | Inflammatory Bowel Disease | - |
dc.subject | Drug-Induced | - |
dc.title | Systemic Lupus Erythematosus in a Patient with Ulcerative Colitis: Co-Existing or Drug-Induced? | - |
dc.type | Article | - |
dc.identifier.email | Chung, HY: jameschy@hku.hk | - |
dc.identifier.authority | Chung, HY=rp02330 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1142/S2661341719720027 | - |
dc.identifier.hkuros | 308498 | - |
dc.identifier.volume | 19 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 67 | - |
dc.identifier.epage | 69 | - |
dc.publisher.place | Singapore | - |
dc.identifier.issnl | 2661-3417 | - |