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Conference Paper: Traditional Chinese Granule Medications are Safe for Decidious Teeth
Title | Traditional Chinese Granule Medications are Safe for Decidious Teeth |
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Authors | |
Issue Date | 2019 |
Publisher | International Association for Dental Research. The Journal's web site is located at http://www.iadr.org/ |
Citation | The 97th General Session of the International Association of Dental Research (IADR) held with the 48th Annual Meeting of the American Association for Dental Research (AADR) & the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), Vancouver, BC, Canada, 19-22 June 2019. In Journal of Dental Research, 2019, v. 98 n. Spec Iss A, article ID: 2127 How to Cite? |
Abstract | Objectives: This study aims to compare and evaluate the in vitro teeth erosive effects of over-the-counter paediatric medication for fever relief, namely two western oral liquids that contains paracetamol and two traditional Chinese granule form medications, on decidious teeth in a continuous scale.
Methods: Twenty enamel block obtained from ten deciduous incisors were randomly assigned into 5 groups (n=4): Group A: paracetamol (Jean marie); Group B: paracetamol (Universal); Group C: Xiao’er Ganmao Keli (Huarun 999); Group D: Xiao’er Chaigui Tuire Keli (Guizhou Bailing); Group E: deionized water (control group). The traditional Chinese medication (Groups C and D) in guanule form were reconstituted in water according to manufacturers' instruction before use. Immersion model was used for 20 rounds for all teeth: in each round i the teeth were immersed to one group of liquid for 15 seconds and then rinsed with deionized water, and then Vickers microhardness (H) were measured. Mean hardness ratio at i-round (MHRi) was established by comparing the hardness at i-round (Hi) divided by 0 round (H0), i.e. before the immersion. In addition, the initial and final surface morphology and chemical analysis of each sample were performed by Scanning Electron Microscope (SEM) and Energy Dispersive X-ray spectroscopy (EDX). The pH of each drugs were measured by pH meter. All statistics were performed at α=0.05.
Results: All groups of drugs exhibited acidic pH (4.74-5.76). After 20 rounds of immersion, the MHR20 of groups A (0.886) and B (0.930) were decreased significantly from the MHR0, whilst groups C (0.978) and D (0/985) illustrated a similar trend with control group E (0.985). SEM revealed distinctive enamel loss with irregular craters in Group A, and Group B showed a corroded surface and the fracture lines along the border of prism heads. Groups C and D were alike, that erosive changes were barely seen, similar to Group E. EDX did not show any significant changes on Ca/P ratio. Despite Ca/C were decreased in all groups, no significant differences were found.
Conclusions: The pH of liquid medication may not be a significant factor that contribuite to enamel softening. Traditional Chinese granule medications might be a safer option for decidious teeth. |
Description | Poster Session: Materials and Biological Research - Final Presentation ID: 2127 |
Persistent Identifier | http://hdl.handle.net/10722/278317 |
DC Field | Value | Language |
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dc.contributor.author | Tsoi, KH | - |
dc.contributor.author | Zhao, D | - |
dc.contributor.author | Matinlinna, JP | - |
dc.contributor.author | Wong, HM | - |
dc.date.accessioned | 2019-10-04T08:11:40Z | - |
dc.date.available | 2019-10-04T08:11:40Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | The 97th General Session of the International Association of Dental Research (IADR) held with the 48th Annual Meeting of the American Association for Dental Research (AADR) & the 43rd Annual Meeting of the Canadian Association for Dental Research (CADR), Vancouver, BC, Canada, 19-22 June 2019. In Journal of Dental Research, 2019, v. 98 n. Spec Iss A, article ID: 2127 | - |
dc.identifier.uri | http://hdl.handle.net/10722/278317 | - |
dc.description | Poster Session: Materials and Biological Research - Final Presentation ID: 2127 | - |
dc.description.abstract | Objectives: This study aims to compare and evaluate the in vitro teeth erosive effects of over-the-counter paediatric medication for fever relief, namely two western oral liquids that contains paracetamol and two traditional Chinese granule form medications, on decidious teeth in a continuous scale. Methods: Twenty enamel block obtained from ten deciduous incisors were randomly assigned into 5 groups (n=4): Group A: paracetamol (Jean marie); Group B: paracetamol (Universal); Group C: Xiao’er Ganmao Keli (Huarun 999); Group D: Xiao’er Chaigui Tuire Keli (Guizhou Bailing); Group E: deionized water (control group). The traditional Chinese medication (Groups C and D) in guanule form were reconstituted in water according to manufacturers' instruction before use. Immersion model was used for 20 rounds for all teeth: in each round i the teeth were immersed to one group of liquid for 15 seconds and then rinsed with deionized water, and then Vickers microhardness (H) were measured. Mean hardness ratio at i-round (MHRi) was established by comparing the hardness at i-round (Hi) divided by 0 round (H0), i.e. before the immersion. In addition, the initial and final surface morphology and chemical analysis of each sample were performed by Scanning Electron Microscope (SEM) and Energy Dispersive X-ray spectroscopy (EDX). The pH of each drugs were measured by pH meter. All statistics were performed at α=0.05. Results: All groups of drugs exhibited acidic pH (4.74-5.76). After 20 rounds of immersion, the MHR20 of groups A (0.886) and B (0.930) were decreased significantly from the MHR0, whilst groups C (0.978) and D (0/985) illustrated a similar trend with control group E (0.985). SEM revealed distinctive enamel loss with irregular craters in Group A, and Group B showed a corroded surface and the fracture lines along the border of prism heads. Groups C and D were alike, that erosive changes were barely seen, similar to Group E. EDX did not show any significant changes on Ca/P ratio. Despite Ca/C were decreased in all groups, no significant differences were found. Conclusions: The pH of liquid medication may not be a significant factor that contribuite to enamel softening. Traditional Chinese granule medications might be a safer option for decidious teeth. | - |
dc.language | eng | - |
dc.publisher | International Association for Dental Research. The Journal's web site is located at http://www.iadr.org/ | - |
dc.relation.ispartof | Journal of Dental Research (Spec Issue) | - |
dc.relation.ispartof | IADR/AADR/CADR 2019 General Session & Exhibition | - |
dc.title | Traditional Chinese Granule Medications are Safe for Decidious Teeth | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Tsoi, KH: jkhtsoi@hku.hk | - |
dc.identifier.email | Matinlinna, JP: jpmat@hku.hk | - |
dc.identifier.email | Wong, HM: wonghmg@hkucc.hku.hk | - |
dc.identifier.authority | Tsoi, KH=rp01609 | - |
dc.identifier.authority | Matinlinna, JP=rp00052 | - |
dc.identifier.authority | Wong, HM=rp00042 | - |
dc.identifier.hkuros | 306501 | - |
dc.identifier.hkuros | 315420 | - |
dc.identifier.volume | 98 | - |
dc.identifier.issue | Spec Iss A | - |
dc.identifier.spage | article ID: 2127 | - |
dc.identifier.epage | article ID: 2127 | - |
dc.publisher.place | United States | - |