File Download
There are no files associated with this item.
Links for fulltext
(May Require Subscription)
- Publisher Website: 10.1016/B978-0-12-813355-2.00007-7
- Scopus: eid_2-s2.0-85071102305
Supplementary
-
Citations:
- Scopus: 0
- Appears in Collections:
Book Chapter: Nanoengineered biomaterial for brain tissue reconstruction and functional repairment
Title | Nanoengineered biomaterial for brain tissue reconstruction and functional repairment |
---|---|
Authors | |
Keywords | Alzheimer’s disease Animal studies Brain neoplasm Cell-based therapy Clinical trials Gene therapy Nanoengineered materials Parkinson’s disease Scaffolds Stroke Tissue engineering Traumatic brain injury |
Issue Date | 2019 |
Publisher | Elsevier |
Citation | Nanoengineered biomaterial for brain tissue reconstruction and functional repairment. In Mozafari, M, Rajadas, J and Kaplan, D (Eds.), Nanoengineered Biomaterials For Regenerative Medicine, p. 145-166. Cham, Switzerland: Elsevier, 2019 How to Cite? |
Abstract | Disease-modifying treatments for reversing acute injuries, chronic degenerations and malignancies in the brain are currently lacking. Although symptomatic control may be achieved by pharmacological means, options for brain tissue reconstruction and functional repair remain limited. With advanced knowledge in disease-causing mechanisms, material science, gene therapy, and neural tissue engineering, several exciting and multifaceted nanoengineering approaches have been proposed. These approaches include NM-mediated gene therapy, NM-mediated neural tissue engineering and cell-mediated for local delivery of NM. Here, the background and current treatments for common brain disorders are introduced, followed by a description of clinical trials designed to repair and regenerate the brain. Nanomaterial (NM)-based strategies that have been applied in vivo are discussed in latter parts of this chapter. |
Persistent Identifier | http://hdl.handle.net/10722/275630 |
ISBN |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Wong, SY | - |
dc.contributor.author | Tsang, KK | - |
dc.contributor.author | Lo, ACY | - |
dc.date.accessioned | 2019-09-10T02:46:27Z | - |
dc.date.available | 2019-09-10T02:46:27Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | Nanoengineered biomaterial for brain tissue reconstruction and functional repairment. In Mozafari, M, Rajadas, J and Kaplan, D (Eds.), Nanoengineered Biomaterials For Regenerative Medicine, p. 145-166. Cham, Switzerland: Elsevier, 2019 | - |
dc.identifier.isbn | 9780128133552 | - |
dc.identifier.uri | http://hdl.handle.net/10722/275630 | - |
dc.description.abstract | Disease-modifying treatments for reversing acute injuries, chronic degenerations and malignancies in the brain are currently lacking. Although symptomatic control may be achieved by pharmacological means, options for brain tissue reconstruction and functional repair remain limited. With advanced knowledge in disease-causing mechanisms, material science, gene therapy, and neural tissue engineering, several exciting and multifaceted nanoengineering approaches have been proposed. These approaches include NM-mediated gene therapy, NM-mediated neural tissue engineering and cell-mediated for local delivery of NM. Here, the background and current treatments for common brain disorders are introduced, followed by a description of clinical trials designed to repair and regenerate the brain. Nanomaterial (NM)-based strategies that have been applied in vivo are discussed in latter parts of this chapter. | - |
dc.language | eng | - |
dc.publisher | Elsevier | - |
dc.relation.ispartof | Nanoengineered Biomaterials For Regenerative Medicine | - |
dc.subject | Alzheimer’s disease | - |
dc.subject | Animal studies | - |
dc.subject | Brain neoplasm | - |
dc.subject | Cell-based therapy | - |
dc.subject | Clinical trials | - |
dc.subject | Gene therapy | - |
dc.subject | Nanoengineered materials | - |
dc.subject | Parkinson’s disease | - |
dc.subject | Scaffolds | - |
dc.subject | Stroke | - |
dc.subject | Tissue engineering | - |
dc.subject | Traumatic brain injury | - |
dc.title | Nanoengineered biomaterial for brain tissue reconstruction and functional repairment | - |
dc.type | Book_Chapter | - |
dc.identifier.email | Wong, SY: frann@hku.hk | - |
dc.identifier.email | Lo, ACY: amylo@hku.hk | - |
dc.identifier.authority | Lo, ACY=rp00425 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1016/B978-0-12-813355-2.00007-7 | - |
dc.identifier.scopus | eid_2-s2.0-85071102305 | - |
dc.identifier.hkuros | 303228 | - |
dc.identifier.spage | 145 | - |
dc.identifier.epage | 166 | - |
dc.publisher.place | Cham, Switzerland | - |