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Article: Repair of dentine-related lesions without a drill or injection

TitleRepair of dentine-related lesions without a drill or injection
Authors
KeywordsElectric fields
Microhardness
In-vivo
Inflammatory reaction
Remineralization
Issue Date2019
PublisherRoyal Society of Chemistry: Open Access. The Journal's web site is located at http://pubs.rsc.org/en/journals/journalissues/ra
Citation
RSC Advances, 2019, v. 9 n. 26, p. 15099-15107 How to Cite?
AbstractFor covering the shortages of traditional treatments, a novel and non-invasive system was developed with the simple adaption of nature's own repair process, while an extrinsic electric field was introduced to improve its remineralization kinetics. In an in vivo study, acid-etched rabbit dentine was used to evaluate the remineralization efficacy and safety of the system. The exposed dentine tubules were fully occluded after 5 hours/1.0 mA and 8 hours/0.5 mA of remineralization. After 5 hours of remineralization (1.0 mA), the micro-hardness of the demineralized dentine was fully recovered, equal to native rabbit dentine. Haematoxylin–eosin staining demonstrated no obvious inflammatory reaction. This study provides a feasible solution to realize rapid repair of dentine.
Persistent Identifierhttp://hdl.handle.net/10722/273826
ISSN
2017 Impact Factor: 2.936
2015 SCImago Journal Rankings: 0.990

 

DC FieldValueLanguage
dc.contributor.authorZhang, YY-
dc.contributor.authorWong, HM-
dc.contributor.authorMcGrath, CPJ-
dc.contributor.authorLi, QL-
dc.date.accessioned2019-08-18T14:49:20Z-
dc.date.available2019-08-18T14:49:20Z-
dc.date.issued2019-
dc.identifier.citationRSC Advances, 2019, v. 9 n. 26, p. 15099-15107-
dc.identifier.issn2046-2069-
dc.identifier.urihttp://hdl.handle.net/10722/273826-
dc.description.abstractFor covering the shortages of traditional treatments, a novel and non-invasive system was developed with the simple adaption of nature's own repair process, while an extrinsic electric field was introduced to improve its remineralization kinetics. In an in vivo study, acid-etched rabbit dentine was used to evaluate the remineralization efficacy and safety of the system. The exposed dentine tubules were fully occluded after 5 hours/1.0 mA and 8 hours/0.5 mA of remineralization. After 5 hours of remineralization (1.0 mA), the micro-hardness of the demineralized dentine was fully recovered, equal to native rabbit dentine. Haematoxylin–eosin staining demonstrated no obvious inflammatory reaction. This study provides a feasible solution to realize rapid repair of dentine.-
dc.languageeng-
dc.publisherRoyal Society of Chemistry: Open Access. The Journal's web site is located at http://pubs.rsc.org/en/journals/journalissues/ra-
dc.relation.ispartofRSC Advances-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectElectric fields-
dc.subjectMicrohardness-
dc.subjectIn-vivo-
dc.subjectInflammatory reaction-
dc.subjectRemineralization-
dc.titleRepair of dentine-related lesions without a drill or injection-
dc.typeArticle-
dc.identifier.emailWong, HM: wonghmg@hkucc.hku.hk-
dc.identifier.emailMcGrath, CPJ: mcgrathc@hkucc.hku.hk-
dc.identifier.authorityWong, HM=rp00042-
dc.identifier.authorityMcGrath, CPJ=rp00037-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1039/C9RA02759A-
dc.identifier.scopuseid_2-s2.0-85065864293-
dc.identifier.hkuros301887-
dc.identifier.volume9-
dc.identifier.issue26-
dc.identifier.spage15099-
dc.identifier.epage15107-
dc.publisher.placeUnited Kingdom-

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