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Article: Thielavins W-Z7, new antifouling thielavins from the marine-derived fungus thielavia sp. UST030930-004

TitleThielavins W-Z7, new antifouling thielavins from the marine-derived fungus thielavia sp. UST030930-004
Authors
Han, ZhuangLi, Yong XinLiu, Ling LiLu, LiangGuo, Xian RongZhang, Xi XiangZhang, Xiao YongQi, Shu HuaXu, YingQian, Pei Yuan
KeywordsThielavia sp.
Marine-derived fungus
Balanus (=Amphibalanus) amphitrite
Antifouling
Thielavins
Issue Date2017
Citation
Marine Drugs, 2017, v. 15, n. 5, article no. 128 How to Cite?
DOI: http://dx.doi.org/10.3390/md15050128
Abstract© 2017 by the authors. Licensee MDPI. Eleven new depsides - thielavins W-Z (1-4) and thielavins Z1-Z7 (5-11) - and also four known thielavins - A, H, J, and K (12-15) - were isolated from the ethyl acetate extract of a marine-derived fungal strain Thielavia sp UST030930-004. All of these compounds were evaluated for antifouling activity against cyprids of the barnacle Balanus (=Amphibalanus) amphitrite. The results showed that compounds 1-3 and 6-13 were active, with EC50 values ranging from 2.95 ± 0.59 to 69.19 ± 9.51 μM, respectively. The inhibitive effect of compounds 1-3 and 7 was reversible. This is the first description of the antifouling activity of thielavins against barnacle cyprids.
Persistent Identifierhttp://hdl.handle.net/10722/273597
ISSN
1660-3397
2021 Impact Factor: 6.085
2020 SCImago Journal Rankings: 0.848
ISI Accession Number ID
WOS:000404235100004

 

DC FieldValueLanguage
dc.contributor.authorHan, Zhuang-
dc.contributor.authorLi, Yong Xin-
dc.contributor.authorLiu, Ling Li-
dc.contributor.authorLu, Liang-
dc.contributor.authorGuo, Xian Rong-
dc.contributor.authorZhang, Xi Xiang-
dc.contributor.authorZhang, Xiao Yong-
dc.contributor.authorQi, Shu Hua-
dc.contributor.authorXu, Ying-
dc.contributor.authorQian, Pei Yuan-
dc.date.accessioned2019-08-12T09:56:05Z-
dc.date.available2019-08-12T09:56:05Z-
dc.date.issued2017-
dc.identifier.citationMarine Drugs, 2017, v. 15, n. 5, article no. 128-
dc.identifier.issn1660-3397-
dc.identifier.urihttp://hdl.handle.net/10722/273597-
dc.description.abstract© 2017 by the authors. Licensee MDPI. Eleven new depsides - thielavins W-Z (1-4) and thielavins Z1-Z7 (5-11) - and also four known thielavins - A, H, J, and K (12-15) - were isolated from the ethyl acetate extract of a marine-derived fungal strain Thielavia sp UST030930-004. All of these compounds were evaluated for antifouling activity against cyprids of the barnacle Balanus (=Amphibalanus) amphitrite. The results showed that compounds 1-3 and 6-13 were active, with EC50 values ranging from 2.95 ± 0.59 to 69.19 ± 9.51 μM, respectively. The inhibitive effect of compounds 1-3 and 7 was reversible. This is the first description of the antifouling activity of thielavins against barnacle cyprids.-
dc.languageeng-
dc.relation.ispartofMarine Drugs-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectThielavia sp.-
dc.subjectMarine-derived fungus-
dc.subjectBalanus (=Amphibalanus) amphitrite-
dc.subjectAntifouling-
dc.subjectThielavins-
dc.titleThielavins W-Z7, new antifouling thielavins from the marine-derived fungus thielavia sp. UST030930-004-
dc.typeArticle-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3390/md15050128-
dc.identifier.pmid28468259-
dc.identifier.scopuseid_2-s2.0-85019562986-
dc.identifier.volume15-
dc.identifier.issue5-
dc.identifier.spagearticle no. 128-
dc.identifier.epagearticle no. 128-
dc.identifier.isiWOS:000404235100004-
dc.identifier.issnl1660-3397-

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