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- Publisher Website: 10.1186/s12871-017-0434-z
- Scopus: eid_2-s2.0-85032174594
- PMID: 29070011
- WOS: WOS:000413763200001
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Article: The obesity conundrum in sepsis
Title | The obesity conundrum in sepsis |
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Authors | |
Keywords | Obesity Overweight Sepsis Septic shock Obesity paradox Mortality ICU Meta-analysis |
Issue Date | 2017 |
Publisher | BioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcanesthesiol/ |
Citation | BMC Anesthesiology, 2017, v. 17, article no. 147 How to Cite? |
Abstract | While the long-term negative effects of obesity on health is a well-studied phenomenon, its effects on acute illnesses seem to be the contrary. Several studies have indicated the possibility of an ‘obesity paradox’ in sepsis – where overweight and obese patients have better outcomes than normal weight patients. These meta-analyses including large numbers of patients across different countries raised an interesting but debatable topic. Results from meta-analyses of observational studies should be interpreted with caution, and a prove of association not be mistaken as prove of causality. Limitations common to such studies include inadequate adjustment for confounding and selection bias. More rigorous investigations to clarify any causal relationship between obesity and mortality in sepsis are needed. |
Persistent Identifier | http://hdl.handle.net/10722/273493 |
ISSN | 2023 Impact Factor: 2.3 2023 SCImago Journal Rankings: 0.658 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ng, PY | - |
dc.contributor.author | Eikermann, M | - |
dc.date.accessioned | 2019-08-12T02:58:54Z | - |
dc.date.available | 2019-08-12T02:58:54Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | BMC Anesthesiology, 2017, v. 17, article no. 147 | - |
dc.identifier.issn | 1471-2253 | - |
dc.identifier.uri | http://hdl.handle.net/10722/273493 | - |
dc.description.abstract | While the long-term negative effects of obesity on health is a well-studied phenomenon, its effects on acute illnesses seem to be the contrary. Several studies have indicated the possibility of an ‘obesity paradox’ in sepsis – where overweight and obese patients have better outcomes than normal weight patients. These meta-analyses including large numbers of patients across different countries raised an interesting but debatable topic. Results from meta-analyses of observational studies should be interpreted with caution, and a prove of association not be mistaken as prove of causality. Limitations common to such studies include inadequate adjustment for confounding and selection bias. More rigorous investigations to clarify any causal relationship between obesity and mortality in sepsis are needed. | - |
dc.language | eng | - |
dc.publisher | BioMed Central Ltd. The Journal's web site is located at http://www.biomedcentral.com/bmcanesthesiol/ | - |
dc.relation.ispartof | BMC Anesthesiology | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Obesity | - |
dc.subject | Overweight | - |
dc.subject | Sepsis | - |
dc.subject | Septic shock | - |
dc.subject | Obesity paradox | - |
dc.subject | Mortality | - |
dc.subject | ICU | - |
dc.subject | Meta-analysis | - |
dc.title | The obesity conundrum in sepsis | - |
dc.type | Article | - |
dc.identifier.email | Ng, PY: pyeungng@hku.hk | - |
dc.identifier.authority | Ng, PY=rp02517 | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1186/s12871-017-0434-z | - |
dc.identifier.pmid | 29070011 | - |
dc.identifier.pmcid | PMC5657099 | - |
dc.identifier.scopus | eid_2-s2.0-85032174594 | - |
dc.identifier.hkuros | 300520 | - |
dc.identifier.volume | 17 | - |
dc.identifier.spage | article no. 147 | - |
dc.identifier.epage | article no. 147 | - |
dc.identifier.isi | WOS:000413763200001 | - |
dc.publisher.place | United Kingdom | - |
dc.identifier.issnl | 1471-2253 | - |