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- Publisher Website: 10.1016/j.semradonc.2014.12.003
- Scopus: eid_2-s2.0-84961289904
- PMID: 25771414
- WOS: WOS:000351254100006
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Article: Nondosimetric Risk Factors for Radiation-Induced Lung Toxicity
Title | Nondosimetric Risk Factors for Radiation-Induced Lung Toxicity |
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Authors | |
Issue Date | 2015 |
Citation | Seminars in Radiation Oncology, 2015, v. 25, n. 2, p. 100-109 How to Cite? |
Abstract | © 2015 The Authors. The decision to administer a radical course of radiotherapy (RT) is largely influenced by the dose-volume metrics of the treatment plan, but what are the patient-related and other factors that may independently increase the risk of radiation lung toxicity? Poor pulmonary function has been regarded as a risk factor and a relative contraindication for patients undergoing radical RT, but recent evidence suggests that patients with poor spirometry results may tolerate conventional or high-dose RT as well as, if not better than, patients with normal function. However, caution may need to be exercised in patients with underlying interstitial pulmonary fibrosis. Furthermore, there is emerging evidence of molecular markers of increased risk of toxicity. This review discusses patient-related risk factors other than dosimetry for radiation lung toxicity. |
Persistent Identifier | http://hdl.handle.net/10722/267028 |
ISSN | 2023 Impact Factor: 2.6 2023 SCImago Journal Rankings: 1.038 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Kong, Feng Ming (Spring) | - |
dc.contributor.author | Wang, Shulian | - |
dc.date.accessioned | 2019-01-31T07:20:18Z | - |
dc.date.available | 2019-01-31T07:20:18Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | Seminars in Radiation Oncology, 2015, v. 25, n. 2, p. 100-109 | - |
dc.identifier.issn | 1053-4296 | - |
dc.identifier.uri | http://hdl.handle.net/10722/267028 | - |
dc.description.abstract | © 2015 The Authors. The decision to administer a radical course of radiotherapy (RT) is largely influenced by the dose-volume metrics of the treatment plan, but what are the patient-related and other factors that may independently increase the risk of radiation lung toxicity? Poor pulmonary function has been regarded as a risk factor and a relative contraindication for patients undergoing radical RT, but recent evidence suggests that patients with poor spirometry results may tolerate conventional or high-dose RT as well as, if not better than, patients with normal function. However, caution may need to be exercised in patients with underlying interstitial pulmonary fibrosis. Furthermore, there is emerging evidence of molecular markers of increased risk of toxicity. This review discusses patient-related risk factors other than dosimetry for radiation lung toxicity. | - |
dc.language | eng | - |
dc.relation.ispartof | Seminars in Radiation Oncology | - |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.title | Nondosimetric Risk Factors for Radiation-Induced Lung Toxicity | - |
dc.type | Article | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1016/j.semradonc.2014.12.003 | - |
dc.identifier.pmid | 25771414 | - |
dc.identifier.scopus | eid_2-s2.0-84961289904 | - |
dc.identifier.volume | 25 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 100 | - |
dc.identifier.epage | 109 | - |
dc.identifier.eissn | 1532-9461 | - |
dc.identifier.isi | WOS:000351254100006 | - |
dc.identifier.issnl | 1053-4296 | - |