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Conference Paper: Neural activity pattern(s) underlying brain interhemispheric propagation: An optogenetic fMRI study
Title | Neural activity pattern(s) underlying brain interhemispheric propagation: An optogenetic fMRI study |
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Authors | |
Issue Date | 2018 |
Publisher | International Society for Magnetic Resonance in Medicine. |
Citation | Proceedings of International Society for Magnetic Resonance in Medicine & The European Society for Magnetic Resonance in Medicine and Biology (ISMRM-ESMRMB) Joint Annual Meeting, Paris, France, 16-21 June 2018, abstract no. 1111 How to Cite? |
Abstract | The sensory system is topographically organized by highly interconnected excitatory thalamo-cortical and interhemispheric cortical-cortical projections. However, little is known at present regarding the existence of spatiotemporal neural activity pattern(s) that may dictate the propagation of activity between cortices at both hemispheres. Here, we employed a novel paired-pulse optogenetic fMRI stimulation paradigm to reveal a temporally-specific neural activity pattern initiated from the somatosensory thalamus that could drive activity propagation from the ipsilateral to contralateral cortex. We found that propagation from the ipsilateral to contralateral somatosensory cortex was facilitated when paired optogenetic stimulation pulses were spaced at 100ms, but not 50ms. |
Description | e-Poster: Preclinical fMRI: Neuroscience & Emerging Techniques - abstract no. 1111 |
Persistent Identifier | http://hdl.handle.net/10722/260719 |
DC Field | Value | Language |
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dc.contributor.author | Leong, ATL | - |
dc.contributor.author | Wang, X | - |
dc.contributor.author | Chan, RW | - |
dc.contributor.author | Halloaoui, KE | - |
dc.contributor.author | Wu, EX | - |
dc.date.accessioned | 2018-09-14T08:46:17Z | - |
dc.date.available | 2018-09-14T08:46:17Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Proceedings of International Society for Magnetic Resonance in Medicine & The European Society for Magnetic Resonance in Medicine and Biology (ISMRM-ESMRMB) Joint Annual Meeting, Paris, France, 16-21 June 2018, abstract no. 1111 | - |
dc.identifier.uri | http://hdl.handle.net/10722/260719 | - |
dc.description | e-Poster: Preclinical fMRI: Neuroscience & Emerging Techniques - abstract no. 1111 | - |
dc.description.abstract | The sensory system is topographically organized by highly interconnected excitatory thalamo-cortical and interhemispheric cortical-cortical projections. However, little is known at present regarding the existence of spatiotemporal neural activity pattern(s) that may dictate the propagation of activity between cortices at both hemispheres. Here, we employed a novel paired-pulse optogenetic fMRI stimulation paradigm to reveal a temporally-specific neural activity pattern initiated from the somatosensory thalamus that could drive activity propagation from the ipsilateral to contralateral cortex. We found that propagation from the ipsilateral to contralateral somatosensory cortex was facilitated when paired optogenetic stimulation pulses were spaced at 100ms, but not 50ms. | - |
dc.language | eng | - |
dc.publisher | International Society for Magnetic Resonance in Medicine. | - |
dc.relation.ispartof | ISMRM-ESMRMB Joint Annual Meeting 2018 | - |
dc.title | Neural activity pattern(s) underlying brain interhemispheric propagation: An optogenetic fMRI study | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Leong, ATL: tlleong@hku.hk | - |
dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
dc.identifier.authority | Wu, EX=rp00193 | - |
dc.identifier.hkuros | 291502 | - |
dc.identifier.spage | abstract no. 1111 | - |
dc.identifier.epage | abstract no. 1111 | - |
dc.publisher.place | United States | - |