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Article: One–Pot Synthesis and Surface Modification of Lauric-Acid-Capped CoFe2O4 Nanoparticles
Title | One–Pot Synthesis and Surface Modification of Lauric-Acid-Capped CoFe2O4 Nanoparticles |
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Authors | |
Keywords | Drug delivery Inverse spinel cobalt ferrite (CoFe₂O₄) One-pot method Surface modification |
Issue Date | 2018 |
Publisher | Institute of Electrical and Electronics Engineers. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=20 |
Citation | IEEE Transactions on Magnetics, 2018, v. 54 n. 11, article no. 2103505 How to Cite? |
Abstract | This paper presents a facile one-pot method to synthesize monodisperse lauric-acid-capped cobalt ferrite nanoparticles (CoFe 2 O 4 NPs)and investigates their potential application as drug carriers for loading and controlled release of doxorubicin (DOX). The lauric-acid-capped CoFe 2 O 4 NPs with a particle size of 15.3 ± 1.7 nm were synthesized via one-pot reaction. Water-soluble lauric-acid-capped CoFe 2 O 4 NPs were obtained through surface modification with cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS). Furthermore, the performance of water-soluble lauric-acid-capped CoFe 2 O 4 NPs for drug delivery was investigated with DOX hydrochloride. The DOX release percentages of CTAB and SDS modified lauric-acid-capped CoFe 2 O 4 NPs are 56.1% and 48.2%, respectively. These results indicated that the modified lauric-acid-capped CoFe 2 O 4 NPs could be utilized as a promising candidate for cancer chemotherapy by making use of their pH-sensitive drug-release properties. |
Persistent Identifier | http://hdl.handle.net/10722/259265 |
ISSN | 2023 Impact Factor: 2.1 2023 SCImago Journal Rankings: 0.729 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Pong, PWT | - |
dc.contributor.author | Teng, Y | - |
dc.date.accessioned | 2018-09-03T04:04:06Z | - |
dc.date.available | 2018-09-03T04:04:06Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | IEEE Transactions on Magnetics, 2018, v. 54 n. 11, article no. 2103505 | - |
dc.identifier.issn | 0018-9464 | - |
dc.identifier.uri | http://hdl.handle.net/10722/259265 | - |
dc.description.abstract | This paper presents a facile one-pot method to synthesize monodisperse lauric-acid-capped cobalt ferrite nanoparticles (CoFe 2 O 4 NPs)and investigates their potential application as drug carriers for loading and controlled release of doxorubicin (DOX). The lauric-acid-capped CoFe 2 O 4 NPs with a particle size of 15.3 ± 1.7 nm were synthesized via one-pot reaction. Water-soluble lauric-acid-capped CoFe 2 O 4 NPs were obtained through surface modification with cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS). Furthermore, the performance of water-soluble lauric-acid-capped CoFe 2 O 4 NPs for drug delivery was investigated with DOX hydrochloride. The DOX release percentages of CTAB and SDS modified lauric-acid-capped CoFe 2 O 4 NPs are 56.1% and 48.2%, respectively. These results indicated that the modified lauric-acid-capped CoFe 2 O 4 NPs could be utilized as a promising candidate for cancer chemotherapy by making use of their pH-sensitive drug-release properties. | - |
dc.language | eng | - |
dc.publisher | Institute of Electrical and Electronics Engineers. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=20 | - |
dc.relation.ispartof | IEEE Transactions on Magnetics | - |
dc.rights | IEEE Transactions on Magnetics. Copyright © Institute of Electrical and Electronics Engineers. | - |
dc.rights | ©20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. | - |
dc.subject | Drug delivery | - |
dc.subject | Inverse spinel cobalt ferrite (CoFe₂O₄) | - |
dc.subject | One-pot method | - |
dc.subject | Surface modification | - |
dc.title | One–Pot Synthesis and Surface Modification of Lauric-Acid-Capped CoFe2O4 Nanoparticles | - |
dc.type | Article | - |
dc.identifier.email | Pong, PWT: ppong@hkucc.hku.hk | - |
dc.identifier.authority | Pong, PWT=rp00217 | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1109/TMAG.2018.2834524 | - |
dc.identifier.scopus | eid_2-s2.0-85047810322 | - |
dc.identifier.hkuros | 288668 | - |
dc.identifier.volume | 54 | - |
dc.identifier.issue | 11 | - |
dc.identifier.spage | article no. 2103505 | - |
dc.identifier.epage | article no. 2103505 | - |
dc.identifier.isi | WOS:000447832100050 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 0018-9464 | - |