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Article: One–Pot Synthesis and Surface Modification of Lauric-Acid-Capped CoFe2O4 Nanoparticles

TitleOne–Pot Synthesis and Surface Modification of Lauric-Acid-Capped CoFe2O4 Nanoparticles
Authors
KeywordsDrug delivery
Inverse spinel cobalt ferrite (CoFe₂O₄)
One-pot method
Surface modification
Issue Date2018
PublisherInstitute of Electrical and Electronics Engineers. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=20
Citation
IEEE Transactions on Magnetics, 2018, v. 54 n. 11, article no. 2103505 How to Cite?
AbstractThis paper presents a facile one-pot method to synthesize monodisperse lauric-acid-capped cobalt ferrite nanoparticles (CoFe 2 O 4 NPs)and investigates their potential application as drug carriers for loading and controlled release of doxorubicin (DOX). The lauric-acid-capped CoFe 2 O 4 NPs with a particle size of 15.3 ± 1.7 nm were synthesized via one-pot reaction. Water-soluble lauric-acid-capped CoFe 2 O 4 NPs were obtained through surface modification with cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS). Furthermore, the performance of water-soluble lauric-acid-capped CoFe 2 O 4 NPs for drug delivery was investigated with DOX hydrochloride. The DOX release percentages of CTAB and SDS modified lauric-acid-capped CoFe 2 O 4 NPs are 56.1% and 48.2%, respectively. These results indicated that the modified lauric-acid-capped CoFe 2 O 4 NPs could be utilized as a promising candidate for cancer chemotherapy by making use of their pH-sensitive drug-release properties.
Persistent Identifierhttp://hdl.handle.net/10722/259265
ISSN
2017 Impact Factor: 1.467
2015 SCImago Journal Rankings: 0.602
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorPong, PWT-
dc.contributor.authorTeng, Y-
dc.date.accessioned2018-09-03T04:04:06Z-
dc.date.available2018-09-03T04:04:06Z-
dc.date.issued2018-
dc.identifier.citationIEEE Transactions on Magnetics, 2018, v. 54 n. 11, article no. 2103505-
dc.identifier.issn0018-9464-
dc.identifier.urihttp://hdl.handle.net/10722/259265-
dc.description.abstractThis paper presents a facile one-pot method to synthesize monodisperse lauric-acid-capped cobalt ferrite nanoparticles (CoFe 2 O 4 NPs)and investigates their potential application as drug carriers for loading and controlled release of doxorubicin (DOX). The lauric-acid-capped CoFe 2 O 4 NPs with a particle size of 15.3 ± 1.7 nm were synthesized via one-pot reaction. Water-soluble lauric-acid-capped CoFe 2 O 4 NPs were obtained through surface modification with cetyltrimethylammonium bromide (CTAB) and sodium dodecyl sulfate (SDS). Furthermore, the performance of water-soluble lauric-acid-capped CoFe 2 O 4 NPs for drug delivery was investigated with DOX hydrochloride. The DOX release percentages of CTAB and SDS modified lauric-acid-capped CoFe 2 O 4 NPs are 56.1% and 48.2%, respectively. These results indicated that the modified lauric-acid-capped CoFe 2 O 4 NPs could be utilized as a promising candidate for cancer chemotherapy by making use of their pH-sensitive drug-release properties.-
dc.languageeng-
dc.publisherInstitute of Electrical and Electronics Engineers. The Journal's web site is located at http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=20-
dc.relation.ispartofIEEE Transactions on Magnetics-
dc.rightsIEEE Transactions on Magnetics. Copyright © Institute of Electrical and Electronics Engineers.-
dc.rights©20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.-
dc.subjectDrug delivery-
dc.subjectInverse spinel cobalt ferrite (CoFe₂O₄)-
dc.subjectOne-pot method-
dc.subjectSurface modification-
dc.titleOne–Pot Synthesis and Surface Modification of Lauric-Acid-Capped CoFe2O4 Nanoparticles-
dc.typeArticle-
dc.identifier.emailPong, PWT: ppong@hkucc.hku.hk-
dc.identifier.authorityPong, PWT=rp00217-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1109/TMAG.2018.2834524-
dc.identifier.hkuros288668-
dc.identifier.volume54-
dc.identifier.issue11-
dc.identifier.spagearticle no. 2103505-
dc.identifier.epagearticle no. 2103505-
dc.identifier.isiWOS:000447832100050-
dc.publisher.placeUnited States-

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