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Conference Paper: Anterior thoracic fatty corner lesions in T1 Magnetic Resonance Imaging are useful for axial Spondyloarthritis diagnosis

TitleAnterior thoracic fatty corner lesions in T1 Magnetic Resonance Imaging are useful for axial Spondyloarthritis diagnosis
Authors
Issue Date2018
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwell-synergy.com/loi/ijrd
Citation
The 20th Asia Pacific League of Associations for Rheumatology Congress (APLAR 2018), Kaohsiung, Taiwan, 6-9 September 2018. In International Journal of Rheumatic Diseases, 2018, v. 21 n. S1, p. 6 How to Cite?
AbstractObjective: A fatty corner lesion (FCL), as defined by fat infiltration at the vertebral corner in T1 Magnetic Resonance Imaging (MRI) sequence, has been reported to be useful in Spondyloarthritis (SpA) diagnosis. Our objective is to systematically evaluate the diagnostic utility of FCLs in a large, multicenter back pain‐MRI cohort in Hong Kong. Method: Three hundred and one patients with back pain were recruited from 3 rheumatology centers. Clinical, biochemical and radiological parameters were collected and all patients underwent a whole spine and sacroiliac (SI) joints MRI. FCLs from C4 to L5 levels were scored. Results were compared to expert‐diagnosed axial SpA to determine the usefulness of FCLs in disease diagnosis. Result: Anterior FCLs of whole or thoracic spine were found to be useful in axial SpA diagnosis. (AUC 0.622; P = 0.003, AUC 0.640; P = 0.001 respectively) Applying FCLs to the Modified New York (MNY) criteria and Assessment of SpondyloArthritis international Society (ASAS) axial SpA criteria, a minimum of 5 FCLs at whole spine level had a sensitivity of 66.4% and 91.6%, specificity of 98.4% and 91.9% respectively. Applying a minimum of 3 FCLs at thoracic spine level to the MNY criteria and ASAS axial SpA criteria yielded a sensitivity of 68.5% and 92.0%, specificity of 95.2% and 93.5% respectively. Three FCLs improves both classification criteria. Conclusion: FCLs are useful in axial SpA diagnosis. A minimum of 3FCLs at the thoracic level is useful for the disease diagnosis.
DescriptionOral paper presentation - clinical
Persistent Identifierhttp://hdl.handle.net/10722/256453
ISSN
2017 Impact Factor: 2.423
2015 SCImago Journal Rankings: 0.536

 

DC FieldValueLanguage
dc.contributor.authorChung, HY-
dc.contributor.authorTsang, HHL-
dc.contributor.authorChan, SCW-
dc.contributor.authorLee, KH-
dc.contributor.authorLau, WCS-
dc.date.accessioned2018-07-20T06:34:55Z-
dc.date.available2018-07-20T06:34:55Z-
dc.date.issued2018-
dc.identifier.citationThe 20th Asia Pacific League of Associations for Rheumatology Congress (APLAR 2018), Kaohsiung, Taiwan, 6-9 September 2018. In International Journal of Rheumatic Diseases, 2018, v. 21 n. S1, p. 6-
dc.identifier.issn1756-1841-
dc.identifier.urihttp://hdl.handle.net/10722/256453-
dc.descriptionOral paper presentation - clinical-
dc.description.abstractObjective: A fatty corner lesion (FCL), as defined by fat infiltration at the vertebral corner in T1 Magnetic Resonance Imaging (MRI) sequence, has been reported to be useful in Spondyloarthritis (SpA) diagnosis. Our objective is to systematically evaluate the diagnostic utility of FCLs in a large, multicenter back pain‐MRI cohort in Hong Kong. Method: Three hundred and one patients with back pain were recruited from 3 rheumatology centers. Clinical, biochemical and radiological parameters were collected and all patients underwent a whole spine and sacroiliac (SI) joints MRI. FCLs from C4 to L5 levels were scored. Results were compared to expert‐diagnosed axial SpA to determine the usefulness of FCLs in disease diagnosis. Result: Anterior FCLs of whole or thoracic spine were found to be useful in axial SpA diagnosis. (AUC 0.622; P = 0.003, AUC 0.640; P = 0.001 respectively) Applying FCLs to the Modified New York (MNY) criteria and Assessment of SpondyloArthritis international Society (ASAS) axial SpA criteria, a minimum of 5 FCLs at whole spine level had a sensitivity of 66.4% and 91.6%, specificity of 98.4% and 91.9% respectively. Applying a minimum of 3 FCLs at thoracic spine level to the MNY criteria and ASAS axial SpA criteria yielded a sensitivity of 68.5% and 92.0%, specificity of 95.2% and 93.5% respectively. Three FCLs improves both classification criteria. Conclusion: FCLs are useful in axial SpA diagnosis. A minimum of 3FCLs at the thoracic level is useful for the disease diagnosis.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://www.blackwell-synergy.com/loi/ijrd-
dc.relation.ispartofInternational Journal of Rheumatic Diseases-
dc.relation.ispartofAsia Pacific League of Associations for Rheumatology Congress (APLAR 2018)-
dc.titleAnterior thoracic fatty corner lesions in T1 Magnetic Resonance Imaging are useful for axial Spondyloarthritis diagnosis-
dc.typeConference_Paper-
dc.identifier.emailChung, HY: jameschy@hku.hk-
dc.identifier.emailLau, WCS: cslau@hku.hk-
dc.identifier.authorityChung, HY=rp02330-
dc.identifier.authorityLau, WCS=rp01348-
dc.identifier.hkuros286164-
dc.identifier.hkuros286170-
dc.identifier.volume21-
dc.identifier.issueS1-
dc.identifier.spage6-
dc.identifier.epage6-
dc.publisher.placeAustralia-

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