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Article: Use of second-line therapies for management of massive primary postpartum hemorrhage

TitleUse of second-line therapies for management of massive primary postpartum hemorrhage
Authors
KeywordsSecond-line therapy
Uterine compression suture
Uterine arterial embolization
Primary postpartum hemorrhage
Hysterectomy
Balloon tamponade
Issue Date2013
Citation
International Journal of Gynecology and Obstetrics, 2013, v. 122, n. 3, p. 238-243 How to Cite?
AbstractObjective To determine rates of use and success of second-line therapies for massive primary postpartum hemorrhage (PPH). Methods A retrospective cohort study was conducted among 91 women who gave birth at Kwong Wah Hospital, Hong Kong, between January 1, 2006, and December 31, 2011. Inclusion criteria were gestational age of at least 24 weeks and massive PPH (defined as blood loss ≥ 1500 mL within 24 hours after birth). Second-line therapies assessed were uterine compression sutures, uterine artery embolization, and balloon tamponade after failure of uterine massage and uterotonic agents to stop bleeding. Results The rate of massive PPH was 2.65 per 1000 births. Second-line therapies were used among 42 women with PPH, equivalent to a rate of 1.23 per 1000 births. Only 21.4% of the women who received second-line therapies required rescue hysterectomy. A rising trend was observed for the use of second-line therapies, whereas the incidence of rescue hysterectomy and estimated blood loss were found to concomitantly decrease. Conclusion Increasing use of second-line therapies among women with massive PPH was associated with a decreasing trend for rescue hysterectomy. Obstetricians should, therefore, consider all available interventions to stop PPH, including early use of second-line options. © 2013 International Federation of Gynecology and Obstetrics.
Persistent Identifierhttp://hdl.handle.net/10722/244151
ISSN
2015 Impact Factor: 1.674
2015 SCImago Journal Rankings: 1.544

 

DC FieldValueLanguage
dc.contributor.authorChan, Lai Ling-
dc.contributor.authorLo, Tsz Kin-
dc.contributor.authorLau, Wai Lam-
dc.contributor.authorLau, Samuel-
dc.contributor.authorLaw, Bassanio-
dc.contributor.authorTsang, Hin Hung-
dc.contributor.authorLeung, Wing Cheong-
dc.date.accessioned2017-08-31T08:56:11Z-
dc.date.available2017-08-31T08:56:11Z-
dc.date.issued2013-
dc.identifier.citationInternational Journal of Gynecology and Obstetrics, 2013, v. 122, n. 3, p. 238-243-
dc.identifier.issn0020-7292-
dc.identifier.urihttp://hdl.handle.net/10722/244151-
dc.description.abstractObjective To determine rates of use and success of second-line therapies for massive primary postpartum hemorrhage (PPH). Methods A retrospective cohort study was conducted among 91 women who gave birth at Kwong Wah Hospital, Hong Kong, between January 1, 2006, and December 31, 2011. Inclusion criteria were gestational age of at least 24 weeks and massive PPH (defined as blood loss ≥ 1500 mL within 24 hours after birth). Second-line therapies assessed were uterine compression sutures, uterine artery embolization, and balloon tamponade after failure of uterine massage and uterotonic agents to stop bleeding. Results The rate of massive PPH was 2.65 per 1000 births. Second-line therapies were used among 42 women with PPH, equivalent to a rate of 1.23 per 1000 births. Only 21.4% of the women who received second-line therapies required rescue hysterectomy. A rising trend was observed for the use of second-line therapies, whereas the incidence of rescue hysterectomy and estimated blood loss were found to concomitantly decrease. Conclusion Increasing use of second-line therapies among women with massive PPH was associated with a decreasing trend for rescue hysterectomy. Obstetricians should, therefore, consider all available interventions to stop PPH, including early use of second-line options. © 2013 International Federation of Gynecology and Obstetrics.-
dc.languageeng-
dc.relation.ispartofInternational Journal of Gynecology and Obstetrics-
dc.subjectSecond-line therapy-
dc.subjectUterine compression suture-
dc.subjectUterine arterial embolization-
dc.subjectPrimary postpartum hemorrhage-
dc.subjectHysterectomy-
dc.subjectBalloon tamponade-
dc.titleUse of second-line therapies for management of massive primary postpartum hemorrhage-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.ijgo.2013.03.027-
dc.identifier.pmid23806248-
dc.identifier.scopuseid_2-s2.0-84880917715-
dc.identifier.volume122-
dc.identifier.issue3-
dc.identifier.spage238-
dc.identifier.epage243-
dc.identifier.eissn1879-3479-

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