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Article: The role of radiofrequency ablation to liver transection surface in patients with close tumor margin of HCC during hepatectomy-a case matched study

TitleThe role of radiofrequency ablation to liver transection surface in patients with close tumor margin of HCC during hepatectomy-a case matched study
Authors
KeywordsClose resection margin
Hepatocellular carcinoma (HCC)
Radiofrequency ablation (RFA)
Case-matched study
Issue Date2017
PublisherAME Publishing Company. The Journal's web site is located at http://tgh.amegroups.com/index
Citation
Translational Gastroenterology and Hepatology, 2017, v. 2, p. 33 How to Cite?
AbstractBackground: To review the outcome of using radiofrequency ablation (RFA) for patients with close resection margin during hepatectomy. Methods: From Oct 2004 to Sept 2013, 862 patients received hepatectomy for hepatocellular carcinoma (HCC) in the Department of Surgery, Queen Mary Hospital in Hong Kong. Fourteen patients received additional RFA because of close resection margin (<1 cm) during the operation for HCC. The result of 28 patients with close liver resection margin was selected for comparison. The two groups of patients were matched in terms of tumor size, tumor number, stage of disease and magnitude of resection. Results: In the RFA group (n=14), the median age of the patients was 58.5 (range, 25–78 years). The median tumor size was 2.25 cm (range, 1.2–12 cm). In the resection alone group (n=28), the median age for the patients was 61 (range, 36–79 years). The median tumor size was 2.7 cm (range, 1–11 cm). There was no difference in terms of liver function assessment between the two groups. There was no RFA related complication recorded during the study period. There was no hospital mortality in both groups. The 1- and 3-year disease free survival was 38.3% and 25.5% respectively in the RFA group vs. 57.4% and 39.3% respectively in the liver resection alone group (P=0.563). The 1- and 3-year overall survival was 81.5% and 69.8% respectively in the RFA group vs .88.4% and 59.9% respectively in the liver resection alone group (P=0.83). Conclusions: RFA to hepatectomy resection surface in patients with close margin is a safe treatment option but its effectiveness on prevention of local recurrence has yet to be confirmed.
Persistent Identifierhttp://hdl.handle.net/10722/243848
ISSN
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorKotewall, CN-
dc.contributor.authorCheung, TT-
dc.contributor.authorShe, WH-
dc.contributor.authorMa, KW-
dc.contributor.authorTsang, HYS-
dc.contributor.authorDai, WC-
dc.contributor.authorChan, ACY-
dc.contributor.authorChok, KSH-
dc.contributor.authorLo, CM-
dc.date.accessioned2017-08-25T03:00:18Z-
dc.date.available2017-08-25T03:00:18Z-
dc.date.issued2017-
dc.identifier.citationTranslational Gastroenterology and Hepatology, 2017, v. 2, p. 33-
dc.identifier.issn2415-1289-
dc.identifier.urihttp://hdl.handle.net/10722/243848-
dc.description.abstractBackground: To review the outcome of using radiofrequency ablation (RFA) for patients with close resection margin during hepatectomy. Methods: From Oct 2004 to Sept 2013, 862 patients received hepatectomy for hepatocellular carcinoma (HCC) in the Department of Surgery, Queen Mary Hospital in Hong Kong. Fourteen patients received additional RFA because of close resection margin (<1 cm) during the operation for HCC. The result of 28 patients with close liver resection margin was selected for comparison. The two groups of patients were matched in terms of tumor size, tumor number, stage of disease and magnitude of resection. Results: In the RFA group (n=14), the median age of the patients was 58.5 (range, 25–78 years). The median tumor size was 2.25 cm (range, 1.2–12 cm). In the resection alone group (n=28), the median age for the patients was 61 (range, 36–79 years). The median tumor size was 2.7 cm (range, 1–11 cm). There was no difference in terms of liver function assessment between the two groups. There was no RFA related complication recorded during the study period. There was no hospital mortality in both groups. The 1- and 3-year disease free survival was 38.3% and 25.5% respectively in the RFA group vs. 57.4% and 39.3% respectively in the liver resection alone group (P=0.563). The 1- and 3-year overall survival was 81.5% and 69.8% respectively in the RFA group vs .88.4% and 59.9% respectively in the liver resection alone group (P=0.83). Conclusions: RFA to hepatectomy resection surface in patients with close margin is a safe treatment option but its effectiveness on prevention of local recurrence has yet to be confirmed.-
dc.languageeng-
dc.publisherAME Publishing Company. The Journal's web site is located at http://tgh.amegroups.com/index-
dc.relation.ispartofTranslational Gastroenterology and Hepatology-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectClose resection margin-
dc.subjectHepatocellular carcinoma (HCC)-
dc.subjectRadiofrequency ablation (RFA)-
dc.subjectCase-matched study-
dc.titleThe role of radiofrequency ablation to liver transection surface in patients with close tumor margin of HCC during hepatectomy-a case matched study-
dc.typeArticle-
dc.identifier.emailCheung, TT: cheung68@hku.hk-
dc.identifier.emailShe, WH: brianshe@hku.hk-
dc.identifier.emailDai, WC: daiwc@hku.hk-
dc.identifier.emailChan, ACY: acchan@hku.hk-
dc.identifier.emailChok, KSH: chok6275@hku.hk-
dc.identifier.emailLo, CM: chungmlo@hkucc.hku.hk-
dc.identifier.authorityCheung, TT=rp02129-
dc.identifier.authorityChan, ACY=rp00310-
dc.identifier.authorityChok, KSH=rp02110-
dc.identifier.authorityLo, CM=rp00412-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.21037/tgh.2017.03.19-
dc.identifier.pmid28529987-
dc.identifier.pmcidPMC5420546-
dc.identifier.scopuseid_2-s2.0-85018307887-
dc.identifier.hkuros274721-
dc.identifier.volume2-
dc.identifier.spage33-
dc.identifier.epage33-
dc.identifier.isiWOS:000404684300006-
dc.publisher.placeHong Kong-

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