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Article: Insight into the contribution of isoprostanoids to the health effects of omega 3 PUFAs

TitleInsight into the contribution of isoprostanoids to the health effects of omega 3 PUFAs
Authors
KeywordsBioactive lipid mediators
Isoprostanes
Isoprostanoids
Lipidomics
Neuroprostanes
Omega 3 PUFAs
Issue Date2017
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/prostaglandins
Citation
Prostaglandins & Other Lipid Mediators, 2017, v. 133, p. 111-122 How to Cite?
AbstractOmega 3 polyunsaturated fatty acids have been reported to confer beneficial health effects notably in the field of cardiovascular and inflammatory diseases. The current knowledge suggests a significant portion of the effects of omega 3 polyunsaturated fatty acids are mediated by their oxygenated metabolites. This review attempts to cover the current literature about the contribution of specific omega 3 oxygenated metabolites, namely omega 3 isoprostanoids, which are produced through free-radical mediated oxidation. A special emphasis has been given to the most biologically relevant omega 3 polyunsaturated fatty acids namely the α-linolenic, eicosapentaenoic and docosahexaenoic acids. The review includes a comprehensive description of the biosynthetic pathways, a summary of studies related to the biological significance of omega 3 isoprostanoids as well as a critical description of analytical development in the field of omega 3 isoprostanoids profiling in biological samples.
Persistent Identifierhttp://hdl.handle.net/10722/241750
ISSN
2017 Impact Factor: 2.991
2015 SCImago Journal Rankings: 1.142
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorJoumard-Cubizolles, L-
dc.contributor.authorLee, CYJ-
dc.contributor.authorVigor, C-
dc.contributor.authorLeung, HH-
dc.contributor.authorBertrand-Michel, J-
dc.contributor.authorGalano, JM-
dc.contributor.authorMazur, A-
dc.contributor.authorDurand, T-
dc.contributor.authorGladine, C-
dc.date.accessioned2017-06-20T01:48:02Z-
dc.date.available2017-06-20T01:48:02Z-
dc.date.issued2017-
dc.identifier.citationProstaglandins & Other Lipid Mediators, 2017, v. 133, p. 111-122-
dc.identifier.issn1098-8823-
dc.identifier.urihttp://hdl.handle.net/10722/241750-
dc.description.abstractOmega 3 polyunsaturated fatty acids have been reported to confer beneficial health effects notably in the field of cardiovascular and inflammatory diseases. The current knowledge suggests a significant portion of the effects of omega 3 polyunsaturated fatty acids are mediated by their oxygenated metabolites. This review attempts to cover the current literature about the contribution of specific omega 3 oxygenated metabolites, namely omega 3 isoprostanoids, which are produced through free-radical mediated oxidation. A special emphasis has been given to the most biologically relevant omega 3 polyunsaturated fatty acids namely the α-linolenic, eicosapentaenoic and docosahexaenoic acids. The review includes a comprehensive description of the biosynthetic pathways, a summary of studies related to the biological significance of omega 3 isoprostanoids as well as a critical description of analytical development in the field of omega 3 isoprostanoids profiling in biological samples.-
dc.languageeng-
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/prostaglandins-
dc.relation.ispartofProstaglandins & Other Lipid Mediators-
dc.subjectBioactive lipid mediators-
dc.subjectIsoprostanes-
dc.subjectIsoprostanoids-
dc.subjectLipidomics-
dc.subjectNeuroprostanes-
dc.subjectOmega 3 PUFAs-
dc.titleInsight into the contribution of isoprostanoids to the health effects of omega 3 PUFAs-
dc.typeArticle-
dc.identifier.emailLee, CYJ: jettylee@hku.hk-
dc.identifier.authorityLee, CYJ=rp01511-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.prostaglandins.2017.05.005-
dc.identifier.scopuseid_2-s2.0-85021234947-
dc.identifier.hkuros272722-
dc.identifier.volume133-
dc.identifier.spage111-
dc.identifier.epage122-
dc.identifier.isiWOS:000418729100016-
dc.publisher.placeUnited States-

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