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Conference Paper: How accurate are transrectal ultrasound guided biopsy and magnetic resonance imaging in staging prostate cancer and will we advise the wrong patient for active surveillance? A retrospective review in Hong Kong

TitleHow accurate are transrectal ultrasound guided biopsy and magnetic resonance imaging in staging prostate cancer and will we advise the wrong patient for active surveillance? A retrospective review in Hong Kong
Authors
Issue Date2017
PublisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/
Citation
22nd Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 20 November 2016. In BJU International, 2017, v. 119 n. suppl. 3, p. 12-13 How to Cite?
AbstractObjectives: To evaluate the accuracy oftransrectal ultrasound guided (TRUS)biopsy and magnetic resonance imaging(MRI) on staging prostate cancer (PCa)and to investigate any predictors ofupstaging of PCa in low risk patients.Patient and methods: 158 consecutiveseries of robotic assisted laparoscopic radi-cal prostatectomy during September 2011to October 2015 was retrospectivelyreviewed.Results: Total 134 patients with availablereport were analysed. The accuracy of later-ality for 12 core systematic TRUS biopsy,MRI and combination were 46.6%, 58.6%and 64.1%. The concordance of TRUSbiopsy, MRI and combination as indicatedby the Cohen Kappa coefficient were 0.21± 0.45, 0.14 ± 0.46 and 0.31 ± 0.68. Inaddition, the PPV, NPV, sensitivity, speci-ficity and accuracy were 25%, 80.2%, 7.4%,94.4% and 76.9% for prediction of extra-capsular extension by MRI scan. PSA density was a predictor of clinicalupstage of disease in low risks patient withodd-ratio of 2.337 (p = 0.024).Conclusion: TRUS biopsy, MRI and incombination had limited predictive valuein evaluating the laterality of tumour andMRI was a specific but not a sensitivetools in assessment of extra-capsularextension. In Chinese patients diagnosedwith low risks PCa and high PSA density,avoid active surveillance as the choice oftreatment.
DescriptionAbstract
Persistent Identifierhttp://hdl.handle.net/10722/241673
ISSN
2017 Impact Factor: 4.688
2015 SCImago Journal Rankings: 2.009

 

DC FieldValueLanguage
dc.contributor.authorChan, YS-
dc.contributor.authorMa, WK-
dc.contributor.authorTsang, CF-
dc.contributor.authorLai, TCT-
dc.contributor.authorWong, JKW-
dc.contributor.authorHo, SHB-
dc.contributor.authorNg, ATL-
dc.contributor.authorTsu, HLJ-
dc.contributor.authorYiu, MK-
dc.date.accessioned2017-06-20T01:46:58Z-
dc.date.available2017-06-20T01:46:58Z-
dc.date.issued2017-
dc.identifier.citation22nd Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 20 November 2016. In BJU International, 2017, v. 119 n. suppl. 3, p. 12-13-
dc.identifier.issn1464-4096-
dc.identifier.urihttp://hdl.handle.net/10722/241673-
dc.descriptionAbstract-
dc.description.abstractObjectives: To evaluate the accuracy oftransrectal ultrasound guided (TRUS)biopsy and magnetic resonance imaging(MRI) on staging prostate cancer (PCa)and to investigate any predictors ofupstaging of PCa in low risk patients.Patient and methods: 158 consecutiveseries of robotic assisted laparoscopic radi-cal prostatectomy during September 2011to October 2015 was retrospectivelyreviewed.Results: Total 134 patients with availablereport were analysed. The accuracy of later-ality for 12 core systematic TRUS biopsy,MRI and combination were 46.6%, 58.6%and 64.1%. The concordance of TRUSbiopsy, MRI and combination as indicatedby the Cohen Kappa coefficient were 0.21± 0.45, 0.14 ± 0.46 and 0.31 ± 0.68. Inaddition, the PPV, NPV, sensitivity, speci-ficity and accuracy were 25%, 80.2%, 7.4%,94.4% and 76.9% for prediction of extra-capsular extension by MRI scan. PSA density was a predictor of clinicalupstage of disease in low risks patient withodd-ratio of 2.337 (p = 0.024).Conclusion: TRUS biopsy, MRI and incombination had limited predictive valuein evaluating the laterality of tumour andMRI was a specific but not a sensitivetools in assessment of extra-capsularextension. In Chinese patients diagnosedwith low risks PCa and high PSA density,avoid active surveillance as the choice oftreatment.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/-
dc.relation.ispartofBJU International-
dc.rightsPreprint This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article]. Authors are not required to remove preprints posted prior to acceptance of the submitted version. Postprint This is the accepted version of the following article: [full citation], which has been published in final form at [Link to final article].-
dc.titleHow accurate are transrectal ultrasound guided biopsy and magnetic resonance imaging in staging prostate cancer and will we advise the wrong patient for active surveillance? A retrospective review in Hong Kong-
dc.typeConference_Paper-
dc.identifier.emailMa, WK: mwk054@hku.hk-
dc.identifier.emailHo, SHB: hobrian@hku.hk-
dc.identifier.emailTsu, HLJ: jamestsu@hku.hk-
dc.identifier.emailYiu, MK: pmkyiu@hku.hk-
dc.identifier.doi10.1111/bju.13768-
dc.identifier.hkuros272645-
dc.identifier.volume119-
dc.identifier.issuesuppl. 3-
dc.identifier.spage12-
dc.identifier.epage13-
dc.publisher.placeUnited Kingdom-
dc.customcontrol.immutablecsl 170713-

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