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Conference Paper: Magnetic resonance imaging (MRI)/ultrasound (US) fusion guided prostate biopsy with an elastic fusion platform: is it useful in the Chinese population?

TitleMagnetic resonance imaging (MRI)/ultrasound (US) fusion guided prostate biopsy with an elastic fusion platform: is it useful in the Chinese population?
Authors
Issue Date2017
PublisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/
Citation
22nd Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 20 November 2016. In BJU International, 2017, v. 119 n. suppl. 3, p. 8 How to Cite?
AbstractObjective: To compare a new modality ofMRI/US fusion guided prostate biopsywith conventional TRUS biopsy in a Chi-nese cohort.Patients and Methods: From July 2015 toJuly 2016, 94 Chinese men with elevatedserum prostate-specific antigen (PSA) of4–20 ng/mL underwent pre-biopsy MRIprostate. Those with suspicious lesion(s)underwent fusion biopsy (targeted + 12-core template biopsy) using the ArtemisTMfusion platform. The biopsy outcomes werecompared with a matched cohort of 250patients with conventional TRUS guided12-core systematic biopsy.Results: An average of 1.7  1.0 MRIlesions/patient was detected in 81 patients.In 58 patients having lesions of intermedi-ate to high suspicion, the overall cancerdetection rate was significantly higher thanconventional biopsy group (41.4 vs 17.6%,p < 0.0001). Targeted biopsy alonedetected more clinically significant cancers(24.1% vs 10.4%, p = 0.005) and yieldedsignificantly longer mean cancer corelength (5.84.2 mm vs 3.63.1 mm,p = 0.03). Targeted biopsy alone wouldhave avoided diagnosis of 75% (6/8) of theclinically insignificant cancers at theexpense of missing 12.5% (2/16) of theclinically significant cancers. The compli-cation rates were similar between the twogroups.Conclusion: MRI/US fusion guided pros-tate biopsy is promising in improving thediagnostic yield in Chinese men with ele-vated PSA.
DescriptionAbstract
Persistent Identifierhttp://hdl.handle.net/10722/241666
ISSN
2017 Impact Factor: 4.688
2015 SCImago Journal Rankings: 2.009

 

DC FieldValueLanguage
dc.contributor.authorMa, WK-
dc.contributor.authorHo, SHB-
dc.contributor.authorWong, JKW-
dc.contributor.authorLai, ASH-
dc.contributor.authorLam, KC-
dc.contributor.authorWong, CKW-
dc.contributor.authorChan, YS-
dc.contributor.authorYip, LKC-
dc.contributor.authorLai, TCT-
dc.contributor.authorTsang, CF-
dc.contributor.authorNg, ATL-
dc.contributor.authorTsu, HLJ-
dc.contributor.authorYiu, MK-
dc.date.accessioned2017-06-20T01:46:53Z-
dc.date.available2017-06-20T01:46:53Z-
dc.date.issued2017-
dc.identifier.citation22nd Annual Scientific Meeting of the Hong Kong Urological Association, Hong Kong, 20 November 2016. In BJU International, 2017, v. 119 n. suppl. 3, p. 8-
dc.identifier.issn1464-4096-
dc.identifier.urihttp://hdl.handle.net/10722/241666-
dc.descriptionAbstract-
dc.description.abstractObjective: To compare a new modality ofMRI/US fusion guided prostate biopsywith conventional TRUS biopsy in a Chi-nese cohort.Patients and Methods: From July 2015 toJuly 2016, 94 Chinese men with elevatedserum prostate-specific antigen (PSA) of4–20 ng/mL underwent pre-biopsy MRIprostate. Those with suspicious lesion(s)underwent fusion biopsy (targeted + 12-core template biopsy) using the ArtemisTMfusion platform. The biopsy outcomes werecompared with a matched cohort of 250patients with conventional TRUS guided12-core systematic biopsy.Results: An average of 1.7  1.0 MRIlesions/patient was detected in 81 patients.In 58 patients having lesions of intermedi-ate to high suspicion, the overall cancerdetection rate was significantly higher thanconventional biopsy group (41.4 vs 17.6%,p < 0.0001). Targeted biopsy alonedetected more clinically significant cancers(24.1% vs 10.4%, p = 0.005) and yieldedsignificantly longer mean cancer corelength (5.84.2 mm vs 3.63.1 mm,p = 0.03). Targeted biopsy alone wouldhave avoided diagnosis of 75% (6/8) of theclinically insignificant cancers at theexpense of missing 12.5% (2/16) of theclinically significant cancers. The compli-cation rates were similar between the twogroups.Conclusion: MRI/US fusion guided pros-tate biopsy is promising in improving thediagnostic yield in Chinese men with ele-vated PSA.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Ltd. The Journal's web site is located at http://www.bjui.org/-
dc.relation.ispartofBJU International-
dc.rightsPreprint This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article]. Authors are not required to remove preprints posted prior to acceptance of the submitted version. Postprint This is the accepted version of the following article: [full citation], which has been published in final form at [Link to final article].-
dc.titleMagnetic resonance imaging (MRI)/ultrasound (US) fusion guided prostate biopsy with an elastic fusion platform: is it useful in the Chinese population?-
dc.typeConference_Paper-
dc.identifier.emailMa, WK: mwk054@hku.hk-
dc.identifier.emailHo, SHB: hobrian@hku.hk-
dc.identifier.emailTsu, HLJ: jamestsu@hku.hk-
dc.identifier.emailYiu, MK: pmkyiu@hku.hk-
dc.identifier.doi10.1111/bju.13768-
dc.identifier.hkuros272634-
dc.identifier.hkuroscsl 170718-
dc.identifier.volume119-
dc.identifier.issuesuppl. 3-
dc.identifier.spage8-
dc.identifier.epage8-
dc.publisher.placeUnited Kingdom-

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