File Download
There are no files associated with this item.
Supplementary
-
Citations:
- Appears in Collections:
Conference Paper: Patients with Pre-Operative Hepatorenal Syndrome (HRS) Have Poorer Long-Term Survival Outcome after Living Donor Liver Transplantation (LDLT)
Title | Patients with Pre-Operative Hepatorenal Syndrome (HRS) Have Poorer Long-Term Survival Outcome after Living Donor Liver Transplantation (LDLT) |
---|---|
Authors | |
Issue Date | 2010 |
Publisher | John Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021 |
Citation | International Liver Transplantation Society (ILTS) 16th Annual International Congress, Hong Kong, 16-19 June 2010. In Liver Transplantation, v. 16 n. Suppl. 1, p. S146, abstract no. P-94 How to Cite? |
Abstract | Background: The aim of this retrospective review is to investigate whether patients with and without pre-operative hepatorenal syndrome (HRS) have comparable long-term survival outcome after live donor liver transplantation (LDLT).
Methods: Patients who had LDLT done from July 1994 to December 2007 were included in the analysis. The median follow-up period was 55 months. First 50 cases and patients with HCC were excluded from analysis.
Results: Total of 177 patients was included in which 34 of them (19.2%) had pre-operative HRS. Signifi cantly more patients with pre-operative HRS, compared to those without, had worse pre-operative liver function test, more pre-operative ICU admission (p<0.001) and early post-operative complications (p<0.001). Signifi cantly more patients with pre-operative type I HRS died during hospital stay (5 vs. 2; p=0.001). Intra-operative blood transfusion was signifi cantly higher (9 units vs. 4 units; p<0.001) and median day of stay in Intensive Care Unit (ICU) was signifi cantly longer in patients with type I HRS (8.5 days vs. 4 days, p=<0.001). The renal function test was signifi cantly worse in patients with pre-operative type I HRS at postoperative one year (Cr 108umol/L vs. Cr 100umol/L; p=0.004) but was comparable
at postoperative fi ve year (Cr 101umol/L vs. Cr 88umol/L; p=0.145). There was signifi cantly worse overall survival in patients with pre-operative HRS (log-rank test, p= 0.000).
Conclusion: Patients with type I HRS had more early post-operative complications and hospital mortality. They also had poorer long-term overall survival when compared to those without preoperative HRS. |
Description | Poster Session I - Outcomes |
Persistent Identifier | http://hdl.handle.net/10722/241097 |
ISSN | 2023 Impact Factor: 4.7 2023 SCImago Journal Rankings: 1.700 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chok, KSH | - |
dc.contributor.author | Lo, CM | - |
dc.contributor.author | Ng, KKC | - |
dc.contributor.author | Chan, SC | - |
dc.contributor.author | Sharr, WW | - |
dc.contributor.author | Chan, ACY | - |
dc.contributor.author | Fan, ST | - |
dc.date.accessioned | 2017-05-24T07:05:28Z | - |
dc.date.available | 2017-05-24T07:05:28Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | International Liver Transplantation Society (ILTS) 16th Annual International Congress, Hong Kong, 16-19 June 2010. In Liver Transplantation, v. 16 n. Suppl. 1, p. S146, abstract no. P-94 | - |
dc.identifier.issn | 1527-6465 | - |
dc.identifier.uri | http://hdl.handle.net/10722/241097 | - |
dc.description | Poster Session I - Outcomes | - |
dc.description.abstract | Background: The aim of this retrospective review is to investigate whether patients with and without pre-operative hepatorenal syndrome (HRS) have comparable long-term survival outcome after live donor liver transplantation (LDLT). Methods: Patients who had LDLT done from July 1994 to December 2007 were included in the analysis. The median follow-up period was 55 months. First 50 cases and patients with HCC were excluded from analysis. Results: Total of 177 patients was included in which 34 of them (19.2%) had pre-operative HRS. Signifi cantly more patients with pre-operative HRS, compared to those without, had worse pre-operative liver function test, more pre-operative ICU admission (p<0.001) and early post-operative complications (p<0.001). Signifi cantly more patients with pre-operative type I HRS died during hospital stay (5 vs. 2; p=0.001). Intra-operative blood transfusion was signifi cantly higher (9 units vs. 4 units; p<0.001) and median day of stay in Intensive Care Unit (ICU) was signifi cantly longer in patients with type I HRS (8.5 days vs. 4 days, p=<0.001). The renal function test was signifi cantly worse in patients with pre-operative type I HRS at postoperative one year (Cr 108umol/L vs. Cr 100umol/L; p=0.004) but was comparable at postoperative fi ve year (Cr 101umol/L vs. Cr 88umol/L; p=0.145). There was signifi cantly worse overall survival in patients with pre-operative HRS (log-rank test, p= 0.000). Conclusion: Patients with type I HRS had more early post-operative complications and hospital mortality. They also had poorer long-term overall survival when compared to those without preoperative HRS. | - |
dc.language | eng | - |
dc.publisher | John Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jtoc/106570021 | - |
dc.relation.ispartof | Liver Transplantation | - |
dc.rights | Liver Transplantation. Copyright © John Wiley & Sons, Inc. | - |
dc.title | Patients with Pre-Operative Hepatorenal Syndrome (HRS) Have Poorer Long-Term Survival Outcome after Living Donor Liver Transplantation (LDLT) | - |
dc.type | Conference_Paper | - |
dc.identifier.email | Chok, KSH: chok6275@hku.hk | - |
dc.identifier.email | Lo, CM: chungmlo@hkucc.hku.hk | - |
dc.identifier.email | Chan, SC: chanlsc@hku.hk | - |
dc.identifier.email | Sharr, WW: wwsharr@hku.hk | - |
dc.identifier.email | Chan, ACY: acchan@hku.hk | - |
dc.identifier.email | Fan, ST: stfan@hku.hk | - |
dc.identifier.authority | Chok, KSH=rp02110 | - |
dc.identifier.authority | Lo, CM=rp00412 | - |
dc.identifier.authority | Chan, SC=rp01568 | - |
dc.identifier.authority | Chan, ACY=rp00310 | - |
dc.identifier.authority | Fan, ST=rp00355 | - |
dc.identifier.doi | 10.1002/lt.22086 | - |
dc.identifier.volume | 16 | - |
dc.identifier.issue | Suppl. 1 | - |
dc.identifier.spage | S146 | - |
dc.identifier.epage | S146 | - |
dc.publisher.place | United States | - |
dc.identifier.issnl | 1527-6465 | - |