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- Publisher Website: 10.1542/peds.2012-1176
- Scopus: eid_2-s2.0-84870567035
- PMID: 23166346
- WOS: WOS:000314802000029
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Article: Effectiveness of lifestyle interventions in child obesity: Systematic review with meta-analysis
Title | Effectiveness of lifestyle interventions in child obesity: Systematic review with meta-analysis |
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Authors | |
Keywords | Cardio-metabolic risks Systematic review Weight loss Adolescent Child Obesity Lifestyle interventions |
Issue Date | 2012 |
Citation | Pediatrics, 2012, v. 130, n. 6 How to Cite? |
Abstract | BACKGROUND AND OBJECTIVES: The effects of lifestyle interventions on cardio-metabolic outcomes in overweight children have not been reviewed systematically. The objective of the study was to examine the impact of lifestyle interventions incorporating a dietary component on both weight change and cardio-metabolic risks in overweight/obese children. METHODS: English-language articles from 1975 to 2010, available from 7 databases, were used as data sources. Two independent reviewers assessed articles against the following eligibility criteria: randomized controlled trial, participants overweight/obese and ≤18 years, comparing lifestyle interventions to no treatment/wait-list control, usual care, or written education materials. Study quality was critically appraised by 2 reviewers using established criteria; Review Manager 5.1 was used for meta-analyses. RESULTS: Of 38 eligible studies, 33 had complete data for meta-analysis on weight change; 15 reported serum lipids, fasting insulin, or blood pressure. Lifestyle interventions produced significant weight loss compared with no-treatment control conditions: BMI (-1.25kg/m2, 95% confidence interval [CI] -2.18 to -0.32) and BMI z score (-0.10, 95% CI -0.18 to -0.02). Studies comparing lifestyle interventions to usual care also resulted in significant immediate (-1.30 kg/m2, 95% CI -1.58 to -1.03) and posttreatment effects (-0.92 kg/m2, 95% CI -1.31 to -0.54) on BMI up to 1 year from baseline. Lifestyle interventions led to significant improvements in low-density lipoprotein cholesterol (-0.30 mmol/L, 95% CI -0.45 to -0.15), triglycerides (-0.15 mmol/L, 95% CI -0.24 to -0.07), fasting insulin (-55.1 pmol/L, 95% CI -71.2 to -39.1) and blood pressure up to 1 year from baseline. No differences were found for high-density lipoprotein cholesterol. CONCLUSIONS: Lifestyle interventions can lead to improvements in weight and cardio-metabolic outcomes. Further research is needed to determine the optimal length, intensity, and long-term effectiveness of lifestyle interventions. Copyright © 2012 by the American Academy of Pediatrics. |
Persistent Identifier | http://hdl.handle.net/10722/236659 |
ISSN | 2023 Impact Factor: 6.2 2023 SCImago Journal Rankings: 2.437 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ho, Mandy | - |
dc.contributor.author | Garnett, Sarah P. | - |
dc.contributor.author | Baur, Louise | - |
dc.contributor.author | Burrows, Tracy | - |
dc.contributor.author | Stewart, Laura | - |
dc.contributor.author | Neve, Melinda | - |
dc.contributor.author | Collins, Clare | - |
dc.date.accessioned | 2016-12-01T09:08:32Z | - |
dc.date.available | 2016-12-01T09:08:32Z | - |
dc.date.issued | 2012 | - |
dc.identifier.citation | Pediatrics, 2012, v. 130, n. 6 | - |
dc.identifier.issn | 0031-4005 | - |
dc.identifier.uri | http://hdl.handle.net/10722/236659 | - |
dc.description.abstract | BACKGROUND AND OBJECTIVES: The effects of lifestyle interventions on cardio-metabolic outcomes in overweight children have not been reviewed systematically. The objective of the study was to examine the impact of lifestyle interventions incorporating a dietary component on both weight change and cardio-metabolic risks in overweight/obese children. METHODS: English-language articles from 1975 to 2010, available from 7 databases, were used as data sources. Two independent reviewers assessed articles against the following eligibility criteria: randomized controlled trial, participants overweight/obese and ≤18 years, comparing lifestyle interventions to no treatment/wait-list control, usual care, or written education materials. Study quality was critically appraised by 2 reviewers using established criteria; Review Manager 5.1 was used for meta-analyses. RESULTS: Of 38 eligible studies, 33 had complete data for meta-analysis on weight change; 15 reported serum lipids, fasting insulin, or blood pressure. Lifestyle interventions produced significant weight loss compared with no-treatment control conditions: BMI (-1.25kg/m2, 95% confidence interval [CI] -2.18 to -0.32) and BMI z score (-0.10, 95% CI -0.18 to -0.02). Studies comparing lifestyle interventions to usual care also resulted in significant immediate (-1.30 kg/m2, 95% CI -1.58 to -1.03) and posttreatment effects (-0.92 kg/m2, 95% CI -1.31 to -0.54) on BMI up to 1 year from baseline. Lifestyle interventions led to significant improvements in low-density lipoprotein cholesterol (-0.30 mmol/L, 95% CI -0.45 to -0.15), triglycerides (-0.15 mmol/L, 95% CI -0.24 to -0.07), fasting insulin (-55.1 pmol/L, 95% CI -71.2 to -39.1) and blood pressure up to 1 year from baseline. No differences were found for high-density lipoprotein cholesterol. CONCLUSIONS: Lifestyle interventions can lead to improvements in weight and cardio-metabolic outcomes. Further research is needed to determine the optimal length, intensity, and long-term effectiveness of lifestyle interventions. Copyright © 2012 by the American Academy of Pediatrics. | - |
dc.language | eng | - |
dc.relation.ispartof | Pediatrics | - |
dc.subject | Cardio-metabolic risks | - |
dc.subject | Systematic review | - |
dc.subject | Weight loss | - |
dc.subject | Adolescent | - |
dc.subject | Child | - |
dc.subject | Obesity | - |
dc.subject | Lifestyle interventions | - |
dc.title | Effectiveness of lifestyle interventions in child obesity: Systematic review with meta-analysis | - |
dc.type | Article | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1542/peds.2012-1176 | - |
dc.identifier.pmid | 23166346 | - |
dc.identifier.scopus | eid_2-s2.0-84870567035 | - |
dc.identifier.volume | 130 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | null | - |
dc.identifier.epage | null | - |
dc.identifier.eissn | 1098-4275 | - |
dc.identifier.isi | WOS:000314802000029 | - |
dc.identifier.issnl | 0031-4005 | - |