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- Publisher Website: 10.1902/jop.2008.070246
- Scopus: eid_2-s2.0-38549109711
- PMID: 18166110
- WOS: WOS:000252256100025
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Article: Exophytic mass of the gingiva as the first manifestation of metastatic pulmonary adenocarcinoma
Title | Exophytic mass of the gingiva as the first manifestation of metastatic pulmonary adenocarcinoma |
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Authors | |
Keywords | Adenocarcinoma Diagnosis Metastasis Oral manifestation |
Issue Date | 2008 |
Citation | Journal of Periodontology, 2008, v. 79, n. 1, p. 187-191 How to Cite? |
Abstract | Background: Metastasis of a malignant tumor to the oral cavity is rare, but it can be the first manifestation of a primary tumor. Methods: The clinicopathologic features of a gingival metastasis originating from lung adenocarcinoma in a female patient are described. A 57-year-old woman showed a rapidly growing, painless, exophytic mass in the left mandibular gingiva. The whole lesion was excised, and histologic and immunohistochemical analyses were performed. Results: The histopathologic sections showed a proliferation of poorly differentiated spindle and pleomorphic cells. Because the differentiation between carcinoma and sarcoma of spindle cell tumors was difficult, additional immunohistochemical evaluation was performed. The intraoral healing after tumor removal was uneventful. The discrepancy between the histopathologic results and the clinical findings led to a thorough examination by the patient's physician. Finally, a biopsy of the lungs confirmed a poorly differentiated adenocarcinoma with multiple metastases, including the oral cavity. Conclusions: An exophytic lesion on the gingiva can be the first sign of metastatic adenocarcinoma to the oral mucosa. This case emphasizes that even apparently benign-looking gingival lesions in anamnestically healthy patients need to be examined histopathologically. |
Persistent Identifier | http://hdl.handle.net/10722/236123 |
ISSN | 2021 Impact Factor: 4.494 2020 SCImago Journal Rankings: 2.036 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Ferrazzini Pozzi, Elena C. | - |
dc.contributor.author | Altermatt, H. J. | - |
dc.contributor.author | Rees, Terry D. | - |
dc.contributor.author | Bornstein, Michael M. | - |
dc.date.accessioned | 2016-11-11T07:43:00Z | - |
dc.date.available | 2016-11-11T07:43:00Z | - |
dc.date.issued | 2008 | - |
dc.identifier.citation | Journal of Periodontology, 2008, v. 79, n. 1, p. 187-191 | - |
dc.identifier.issn | 0022-3492 | - |
dc.identifier.uri | http://hdl.handle.net/10722/236123 | - |
dc.description.abstract | Background: Metastasis of a malignant tumor to the oral cavity is rare, but it can be the first manifestation of a primary tumor. Methods: The clinicopathologic features of a gingival metastasis originating from lung adenocarcinoma in a female patient are described. A 57-year-old woman showed a rapidly growing, painless, exophytic mass in the left mandibular gingiva. The whole lesion was excised, and histologic and immunohistochemical analyses were performed. Results: The histopathologic sections showed a proliferation of poorly differentiated spindle and pleomorphic cells. Because the differentiation between carcinoma and sarcoma of spindle cell tumors was difficult, additional immunohistochemical evaluation was performed. The intraoral healing after tumor removal was uneventful. The discrepancy between the histopathologic results and the clinical findings led to a thorough examination by the patient's physician. Finally, a biopsy of the lungs confirmed a poorly differentiated adenocarcinoma with multiple metastases, including the oral cavity. Conclusions: An exophytic lesion on the gingiva can be the first sign of metastatic adenocarcinoma to the oral mucosa. This case emphasizes that even apparently benign-looking gingival lesions in anamnestically healthy patients need to be examined histopathologically. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of Periodontology | - |
dc.subject | Adenocarcinoma | - |
dc.subject | Diagnosis | - |
dc.subject | Metastasis | - |
dc.subject | Oral manifestation | - |
dc.title | Exophytic mass of the gingiva as the first manifestation of metastatic pulmonary adenocarcinoma | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1902/jop.2008.070246 | - |
dc.identifier.pmid | 18166110 | - |
dc.identifier.scopus | eid_2-s2.0-38549109711 | - |
dc.identifier.volume | 79 | - |
dc.identifier.issue | 1 | - |
dc.identifier.spage | 187 | - |
dc.identifier.epage | 191 | - |
dc.identifier.isi | WOS:000252256100025 | - |
dc.identifier.issnl | 0022-3492 | - |