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Article: Clinical trials of silver diamine fluoride in arresting caries among children: a systematic review

TitleClinical trials of silver diamine fluoride in arresting caries among children: a systematic review
Authors
Issue Date2016
PublisherSAGE Publications. The Journal's web site is located at http://jct.sagepub.com/
Citation
JDR Clinical & Translational Research, 2016, v. 1 n. 3, p. 201-210 How to Cite?
AbstractThis review aims to investigate the clinical effectiveness of silver diamine fluoride (SDF) in arresting dental caries among children. A systematic search of publications was conducted with the key words “silver diamine fluoride,” “silver diammine fluoride,” “silver fluoride,” “diamine silver fluoride,” or “diammine silver fluoride” as well as their translation in Chinese, Japanese, Portuguese, and Spanish in 7 databases: PubMed (English), Embase (English), Scopus (English), China National Knowledge Infrastructure (Chinese), Ichushi-web (Japanese), Biblioteca Virtual em Saude (Portuguese), and Biblioteca Virtual en Salud Espana (Spanish). Duplicated publications were deleted. The title and abstract were screened and irrelevant publications were excluded. The full text of the remaining publications was retrieved. Prospective clinical studies of SDF that reported a caries-arresting effect among children were included. Meta-analysis was performed for quantitative analysis. A total of 1,123 publications were found, including 19 publications of clinical trials. Sixteen clinical trials studied the caries-arresting effect on primary teeth, and 3 clinical trials were on permanent teeth. Fourteen studies used 38% SDF, 3 used 30% SDF, and 2 used 10% SDF. Meta-analysis was performed on extracted data from 8 studies using 38% SDF to arrest caries in primary teeth. The overall percentage of active caries that became arrested was 81% (95% confidence interval, 68% to 89%; P < 0.001). Apart from staining the arrested lesion black, no significant complication of SDF use among children was reported. SDF was commonly used at 38%. It was effective in arresting dentine caries in primary teeth among children.
Persistent Identifierhttp://hdl.handle.net/10722/234467
ISSN

 

DC FieldValueLanguage
dc.contributor.authorGao, S-
dc.contributor.authorZhao, S-
dc.contributor.authorHiraishi, N-
dc.contributor.authorDuangthip, D-
dc.contributor.authorMei, L-
dc.contributor.authorLo, ECM-
dc.contributor.authorChu, CH-
dc.date.accessioned2016-10-14T13:47:04Z-
dc.date.available2016-10-14T13:47:04Z-
dc.date.issued2016-
dc.identifier.citationJDR Clinical & Translational Research, 2016, v. 1 n. 3, p. 201-210-
dc.identifier.issn2380-0844-
dc.identifier.urihttp://hdl.handle.net/10722/234467-
dc.description.abstractThis review aims to investigate the clinical effectiveness of silver diamine fluoride (SDF) in arresting dental caries among children. A systematic search of publications was conducted with the key words “silver diamine fluoride,” “silver diammine fluoride,” “silver fluoride,” “diamine silver fluoride,” or “diammine silver fluoride” as well as their translation in Chinese, Japanese, Portuguese, and Spanish in 7 databases: PubMed (English), Embase (English), Scopus (English), China National Knowledge Infrastructure (Chinese), Ichushi-web (Japanese), Biblioteca Virtual em Saude (Portuguese), and Biblioteca Virtual en Salud Espana (Spanish). Duplicated publications were deleted. The title and abstract were screened and irrelevant publications were excluded. The full text of the remaining publications was retrieved. Prospective clinical studies of SDF that reported a caries-arresting effect among children were included. Meta-analysis was performed for quantitative analysis. A total of 1,123 publications were found, including 19 publications of clinical trials. Sixteen clinical trials studied the caries-arresting effect on primary teeth, and 3 clinical trials were on permanent teeth. Fourteen studies used 38% SDF, 3 used 30% SDF, and 2 used 10% SDF. Meta-analysis was performed on extracted data from 8 studies using 38% SDF to arrest caries in primary teeth. The overall percentage of active caries that became arrested was 81% (95% confidence interval, 68% to 89%; P < 0.001). Apart from staining the arrested lesion black, no significant complication of SDF use among children was reported. SDF was commonly used at 38%. It was effective in arresting dentine caries in primary teeth among children.-
dc.languageeng-
dc.publisherSAGE Publications. The Journal's web site is located at http://jct.sagepub.com/-
dc.relation.ispartofJDR Clinical & Translational Research-
dc.rightsJDR Clinical & Translational Research. Copyright © SAGE Publications.-
dc.titleClinical trials of silver diamine fluoride in arresting caries among children: a systematic review-
dc.typeArticle-
dc.identifier.emailDuangthip, D: dduang@hku.hk-
dc.identifier.emailMei, L: mei1123@hku.hk-
dc.identifier.emailLo, ECM: edward-lo@hku.hk-
dc.identifier.emailChu, CH: chchu@hku.hk-
dc.identifier.authorityMei, L=rp01840-
dc.identifier.authorityLo, ECM=rp00015-
dc.identifier.authorityChu, CH=rp00022-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1177/2380084416661474-
dc.identifier.hkuros269094-
dc.identifier.volume1-
dc.identifier.issue3-
dc.identifier.spage201-
dc.identifier.epage210-
dc.publisher.placeUnited Kingdom-
dc.customcontrol.immutablesml 161102-

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