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Article: Comparison between the original and shortened versions of the National Institutes of Health Stroke Scale in ischemic stroke patients of intermediate severity

TitleComparison between the original and shortened versions of the National Institutes of Health Stroke Scale in ischemic stroke patients of intermediate severity
Authors
Issue Date2016
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://stroke.ahajournals.org
Citation
Stroke, 2016, v. 47 n. 1, p. 236-239 How to Cite?
AbstractBackground and Purpose: The 15-item National Institutes of Health Stroke Scale (NIHSS) has been critiqued for its complexity and variability, and shortened versions have been proposed. This study aimed to compare the measurement properties of the original version with 3 shortened versions with 11, 8, and 5 items, respectively. Methods: Analyses were performed using data from an international, double-blind randomized controlled trial investigating the efficacy of MLC601 on stroke recovery in patients with ischemic stroke of intermediate severity (Chinese Medicine Neuroaid Efficacy on Stroke recovery [CHIMES]). To compare discriminative ability and responsiveness to change, the effect sizes of the NIHSS scores in relation to modified Rankin Scale, mini-mental status examination, and Barthel index were estimated using regression analysis. Results: For both discriminative ability and responsiveness to change, the original version exhibited a larger effect size (0.55 and 0.84) in relation to modified Rankin Scale than the other 3 shortened versions (0.35–0.46 and 0.74–0.78). Conclusions: The original 15-item NIHSS retained information that made it more discriminative and responsive to change than the shortened versions. We recommend future clinical researchers to use the full version NIHSS to evaluate patients’ stroke severity.
Persistent Identifierhttp://hdl.handle.net/10722/233571
ISSN
2015 Impact Factor: 5.787
2015 SCImago Journal Rankings: 3.671

 

DC FieldValueLanguage
dc.contributor.authorLee, CF-
dc.contributor.authorVenketasubramanian, N-
dc.contributor.authorWong, KSL-
dc.contributor.authorChen, CLH-
dc.date.accessioned2016-09-20T05:37:41Z-
dc.date.available2016-09-20T05:37:41Z-
dc.date.issued2016-
dc.identifier.citationStroke, 2016, v. 47 n. 1, p. 236-239-
dc.identifier.issn0039-2499-
dc.identifier.urihttp://hdl.handle.net/10722/233571-
dc.description.abstractBackground and Purpose: The 15-item National Institutes of Health Stroke Scale (NIHSS) has been critiqued for its complexity and variability, and shortened versions have been proposed. This study aimed to compare the measurement properties of the original version with 3 shortened versions with 11, 8, and 5 items, respectively. Methods: Analyses were performed using data from an international, double-blind randomized controlled trial investigating the efficacy of MLC601 on stroke recovery in patients with ischemic stroke of intermediate severity (Chinese Medicine Neuroaid Efficacy on Stroke recovery [CHIMES]). To compare discriminative ability and responsiveness to change, the effect sizes of the NIHSS scores in relation to modified Rankin Scale, mini-mental status examination, and Barthel index were estimated using regression analysis. Results: For both discriminative ability and responsiveness to change, the original version exhibited a larger effect size (0.55 and 0.84) in relation to modified Rankin Scale than the other 3 shortened versions (0.35–0.46 and 0.74–0.78). Conclusions: The original 15-item NIHSS retained information that made it more discriminative and responsive to change than the shortened versions. We recommend future clinical researchers to use the full version NIHSS to evaluate patients’ stroke severity.-
dc.languageeng-
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://stroke.ahajournals.org-
dc.relation.ispartofStroke-
dc.rightsThis is a non-final version of an article published in final form in (provide complete journal citation)-
dc.titleComparison between the original and shortened versions of the National Institutes of Health Stroke Scale in ischemic stroke patients of intermediate severity-
dc.typeArticle-
dc.identifier.emailLee, CF: fanlee@hkucc.hku.hk-
dc.identifier.authorityLee, CF=rp02103-
dc.identifier.doi10.1161/STROKEAHA.115.011657-
dc.identifier.hkuros267012-
dc.identifier.volume47-
dc.identifier.issue1-
dc.identifier.spage236-
dc.identifier.epage239-
dc.publisher.placeUnited States-

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