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Article: Real-time estimation of the hospitalization fatality risk of influenza A(H1N1)pdm09 in Hong Kong

TitleReal-time estimation of the hospitalization fatality risk of influenza A(H1N1)pdm09 in Hong Kong
Authors
KeywordsEpidemiology
Influenza A
Issue Date2016
PublisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=HYG
Citation
Epidemiology and Infection, 2016, v. 144 n. 8, p. 1579-1583 How to Cite?
AbstractDuring the early stage of an epidemic, timely and reliable estimation of the severity of infections are important for predicting the impact that the influenza viruses will have in the population. We obtained age-specific deaths and hospitalizations for patients with laboratory-confirmed H1N1pdm09 infections from June 2009 to December 2009 in Hong Kong. We retrospectively obtained the real-time estimates of the hospitalization fatality risk (HFR), using crude estimation or allowing for right-censoring for final status in some patients. Models accounting for right-censoring performed better than models without adjustments. The risk of deaths in hospitalized patients with confirmed H1N1pdm09 increased with age. Reliable estimates of the HFR could be obtained before the peak of the first wave of H1N1pdm09 in young and middle-aged adults but after the peak in the elderly. In the next influenza pandemic, timely estimation of the HFR will contribute to risk assessment and disease control.
Persistent Identifierhttp://hdl.handle.net/10722/233539
ISSN
2017 Impact Factor: 2.044
2015 SCImago Journal Rankings: 1.320
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWong, JY-
dc.contributor.authorWu, P-
dc.contributor.authorLau, EHY-
dc.contributor.authorTsang, TK-
dc.contributor.authorFang, VJ-
dc.contributor.authorHo, LM-
dc.contributor.authorCowling, BJ-
dc.date.accessioned2016-09-20T05:37:27Z-
dc.date.available2016-09-20T05:37:27Z-
dc.date.issued2016-
dc.identifier.citationEpidemiology and Infection, 2016, v. 144 n. 8, p. 1579-1583-
dc.identifier.issn0950-2688-
dc.identifier.urihttp://hdl.handle.net/10722/233539-
dc.description.abstractDuring the early stage of an epidemic, timely and reliable estimation of the severity of infections are important for predicting the impact that the influenza viruses will have in the population. We obtained age-specific deaths and hospitalizations for patients with laboratory-confirmed H1N1pdm09 infections from June 2009 to December 2009 in Hong Kong. We retrospectively obtained the real-time estimates of the hospitalization fatality risk (HFR), using crude estimation or allowing for right-censoring for final status in some patients. Models accounting for right-censoring performed better than models without adjustments. The risk of deaths in hospitalized patients with confirmed H1N1pdm09 increased with age. Reliable estimates of the HFR could be obtained before the peak of the first wave of H1N1pdm09 in young and middle-aged adults but after the peak in the elderly. In the next influenza pandemic, timely estimation of the HFR will contribute to risk assessment and disease control.-
dc.languageeng-
dc.publisherCambridge University Press. The Journal's web site is located at http://journals.cambridge.org/action/displayJournal?jid=HYG-
dc.relation.ispartofEpidemiology and Infection-
dc.subjectEpidemiology-
dc.subjectInfluenza A-
dc.titleReal-time estimation of the hospitalization fatality risk of influenza A(H1N1)pdm09 in Hong Kong-
dc.typeArticle-
dc.identifier.emailWong, JY: wongytj@hku.hk-
dc.identifier.emailWu, P: pengwu@hku.hk-
dc.identifier.emailLau, EHY: ehylau@hku.hk-
dc.identifier.emailTsang, TK: matklab@hku.hk-
dc.identifier.emailFang, VJ: vickyf@hku.hk-
dc.identifier.emailHo, LM: lmho@hkucc.hku.hk-
dc.identifier.emailCowling, BJ: bcowling@hku.hk-
dc.identifier.authorityWu, P=rp02025-
dc.identifier.authorityLau, EHY=rp01349-
dc.identifier.authorityTsang, TK=rp02571-
dc.identifier.authorityHo, LM=rp00360-
dc.identifier.authorityCowling, BJ=rp01326-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1017/S0950268815003179-
dc.identifier.pmid27125572-
dc.identifier.pmcidPMC5528870-
dc.identifier.scopuseid_2-s2.0-84979234414-
dc.identifier.hkuros263527-
dc.identifier.volume144-
dc.identifier.issue8-
dc.identifier.spage1579-
dc.identifier.epage1583-
dc.identifier.isiWOS:000375804300001-
dc.publisher.placeUnited Kingdom-

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