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Conference Paper: Functionalized gold nanorod core-mesoporous silica shell nanodevices with controlled release of anticancer drug

TitleFunctionalized gold nanorod core-mesoporous silica shell nanodevices with controlled release of anticancer drug
Authors
KeywordsTemperature
Drug delivery
Functionalization
Biomedical application
Issue Date2016
Citation
The 10th World Biomaterials Congress (WBC 2016), Montreal, Canada, 17-22 May 2016. How to Cite?
AbstractINTRODUCTION: Gold nanorods (AuNRs) can find many biomedical applications including photothermal therapy [1]. AuNRs are normally coated with cetyltrimethyl ammonium bromide (CTAB) when synthesized via seed-mediated growth, resulting in cytotoxicity and low stability which hinder their medical applications. Coating silica on AuNRs may solve the problem and also makes it possible to conjugate targeting ligands to AuNRs [2]. But the shape and thickness control and functionalization of silica shell are the challenges. The reported methods for coating silica often lack reproducibility and also require precise control of CTAB concentration in AuNR stock solution [3]. This investigation developed a facile method to make folic acid modified AuNR core-mesoporous silica shell (AuNR@mSiO2) nanodevices for anti-cancer applications ...
DescriptionTopic: Nano-structured materials for unique functions
Persistent Identifierhttp://hdl.handle.net/10722/232388

 

DC FieldValueLanguage
dc.contributor.authorGuan, Q-
dc.contributor.authorWang, M-
dc.date.accessioned2016-09-20T05:29:38Z-
dc.date.available2016-09-20T05:29:38Z-
dc.date.issued2016-
dc.identifier.citationThe 10th World Biomaterials Congress (WBC 2016), Montreal, Canada, 17-22 May 2016.-
dc.identifier.urihttp://hdl.handle.net/10722/232388-
dc.descriptionTopic: Nano-structured materials for unique functions-
dc.description.abstractINTRODUCTION: Gold nanorods (AuNRs) can find many biomedical applications including photothermal therapy [1]. AuNRs are normally coated with cetyltrimethyl ammonium bromide (CTAB) when synthesized via seed-mediated growth, resulting in cytotoxicity and low stability which hinder their medical applications. Coating silica on AuNRs may solve the problem and also makes it possible to conjugate targeting ligands to AuNRs [2]. But the shape and thickness control and functionalization of silica shell are the challenges. The reported methods for coating silica often lack reproducibility and also require precise control of CTAB concentration in AuNR stock solution [3]. This investigation developed a facile method to make folic acid modified AuNR core-mesoporous silica shell (AuNR@mSiO2) nanodevices for anti-cancer applications ...-
dc.languageeng-
dc.relation.ispartofWorld Biomaterials Congress, WBC 2016-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.subjectTemperature-
dc.subjectDrug delivery-
dc.subjectFunctionalization-
dc.subjectBiomedical application-
dc.titleFunctionalized gold nanorod core-mesoporous silica shell nanodevices with controlled release of anticancer drug-
dc.typeConference_Paper-
dc.identifier.emailWang, M: memwang@hku.hk-
dc.identifier.authorityWang, M=rp00185-
dc.description.naturepostprint-
dc.identifier.doi10.3389/conf.FBIOE.2016.01.01053-
dc.identifier.hkuros264857-

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