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Article: Supportive periodontal therapy using mechanical instrumentation or 2% minocycline gel: A 12 month randomized, controlled, single masked pilot study

TitleSupportive periodontal therapy using mechanical instrumentation or 2% minocycline gel: A 12 month randomized, controlled, single masked pilot study
Authors
KeywordsPeriodontal disease
Microbiology
Maintenance
Clinical trial
Supportive care
Issue Date2006
Citation
Journal of Clinical Periodontology, 2006, v. 33, n. 2, p. 141-150 How to Cite?
AbstractObjective: To compare the short-term performance of subgingival local delivery of 2% minocycline gel and conventional subgingival debridement in supportive periodontal therapy (SPT) patients. Methods: Forty adult patients having completed active treatment for moderate to advanced chronic periodontitis were included in a randomized, controlled, single masked maintenance care pilot study. Sites with residual pocket probing depths ≥5 mm and bleeding on probing were treated with either minocycline gel (minocycline-group) or scaling and root planing only (debridement-group) at baseline, 3, 6, and 9 months. Clinical and microbiological examinations were performed at baseline, 3, 6, 9, and 12 months. Results: Full-mouth plaque and bleeding scores remained <10% and <20%, respectively, for both groups throughout the study. In both groups there was a persistent reduction in number of teeth and sites with probing pocket depths ≥5 mm (p<0.05) with no significant differences between the groups. The prevalence of Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Prevotella nigrescens, remained at levels ≤105 in the majority of patients and sites in both groups. Conclusion: This pilot study failed to show a difference between local delivery of 2% minocycline gel as mono-therapy and traditional subgingival debridement in patients on SPT. © Blackwell Munksgaard 2006.
Persistent Identifierhttp://hdl.handle.net/10722/230763
ISSN
2015 Impact Factor: 3.915
2015 SCImago Journal Rankings: 1.848

 

DC FieldValueLanguage
dc.contributor.authorMcColl, E.-
dc.contributor.authorPatel, K.-
dc.contributor.authorDahlen, G.-
dc.contributor.authorTonetti, M.-
dc.contributor.authorGraziani, F.-
dc.contributor.authorSuvan, J.-
dc.contributor.authorLaurell, L.-
dc.date.accessioned2016-09-01T06:06:44Z-
dc.date.available2016-09-01T06:06:44Z-
dc.date.issued2006-
dc.identifier.citationJournal of Clinical Periodontology, 2006, v. 33, n. 2, p. 141-150-
dc.identifier.issn0303-6979-
dc.identifier.urihttp://hdl.handle.net/10722/230763-
dc.description.abstractObjective: To compare the short-term performance of subgingival local delivery of 2% minocycline gel and conventional subgingival debridement in supportive periodontal therapy (SPT) patients. Methods: Forty adult patients having completed active treatment for moderate to advanced chronic periodontitis were included in a randomized, controlled, single masked maintenance care pilot study. Sites with residual pocket probing depths ≥5 mm and bleeding on probing were treated with either minocycline gel (minocycline-group) or scaling and root planing only (debridement-group) at baseline, 3, 6, and 9 months. Clinical and microbiological examinations were performed at baseline, 3, 6, 9, and 12 months. Results: Full-mouth plaque and bleeding scores remained <10% and <20%, respectively, for both groups throughout the study. In both groups there was a persistent reduction in number of teeth and sites with probing pocket depths ≥5 mm (p<0.05) with no significant differences between the groups. The prevalence of Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Prevotella nigrescens, remained at levels ≤105 in the majority of patients and sites in both groups. Conclusion: This pilot study failed to show a difference between local delivery of 2% minocycline gel as mono-therapy and traditional subgingival debridement in patients on SPT. © Blackwell Munksgaard 2006.-
dc.languageeng-
dc.relation.ispartofJournal of Clinical Periodontology-
dc.subjectPeriodontal disease-
dc.subjectMicrobiology-
dc.subjectMaintenance-
dc.subjectClinical trial-
dc.subjectSupportive care-
dc.titleSupportive periodontal therapy using mechanical instrumentation or 2% minocycline gel: A 12 month randomized, controlled, single masked pilot study-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1111/j.1600-051X.2005.00879.x-
dc.identifier.pmid16441740-
dc.identifier.scopuseid_2-s2.0-33645094656-
dc.identifier.volume33-
dc.identifier.issue2-
dc.identifier.spage141-
dc.identifier.epage150-
dc.identifier.eissn1600-051X-

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