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Article: Severe periodontitis in Marfan's syndrome: A case report

TitleSevere periodontitis in Marfan's syndrome: A case report
Authors
KeywordsFibrillin
Genes
Oral manifestations
Marfan syndrome
Periodontitis/etiology
Connective tissue diseases
Issue Date2002
Citation
Journal of Periodontology, 2002, v. 73, n. 7, p. 823-826 How to Cite?
AbstractBackground: Connective tissue disorders, such as some forms of Ehlers-Danlos syndrome, have been associated with severe periodontitis. Methods: This report describes a case of Marfan's syndrome, an inherited disorder of connective tissue caused by mutations in the fibrillin-1 gene, in which the patient presented with severe periodontitis. Results: At examination, an average full-mouth clinical attachment level loss of 5.6 ± 2.1 mm, furcation involvement, and severe alveolar bone loss were observed in a 41-year-old Caucasian male. Tooth hypermobility was also present. Conclusions: This case appears to be the first documentation of severe periodontitis in a patient with Marfan's syndrome. It supports the hypothesis that a variety of connective tissue disorders may confer increased susceptibility to periodontal tissue breakdown.
Persistent Identifierhttp://hdl.handle.net/10722/230715
ISSN
2015 Impact Factor: 2.844
2015 SCImago Journal Rankings: 1.070

 

DC FieldValueLanguage
dc.contributor.authorStraub, Antje M.-
dc.contributor.authorGrahame, Rodney-
dc.contributor.authorScully, Crispian-
dc.contributor.authorTonetti, Maurizio S.-
dc.date.accessioned2016-09-01T06:06:37Z-
dc.date.available2016-09-01T06:06:37Z-
dc.date.issued2002-
dc.identifier.citationJournal of Periodontology, 2002, v. 73, n. 7, p. 823-826-
dc.identifier.issn0022-3492-
dc.identifier.urihttp://hdl.handle.net/10722/230715-
dc.description.abstractBackground: Connective tissue disorders, such as some forms of Ehlers-Danlos syndrome, have been associated with severe periodontitis. Methods: This report describes a case of Marfan's syndrome, an inherited disorder of connective tissue caused by mutations in the fibrillin-1 gene, in which the patient presented with severe periodontitis. Results: At examination, an average full-mouth clinical attachment level loss of 5.6 ± 2.1 mm, furcation involvement, and severe alveolar bone loss were observed in a 41-year-old Caucasian male. Tooth hypermobility was also present. Conclusions: This case appears to be the first documentation of severe periodontitis in a patient with Marfan's syndrome. It supports the hypothesis that a variety of connective tissue disorders may confer increased susceptibility to periodontal tissue breakdown.-
dc.languageeng-
dc.relation.ispartofJournal of Periodontology-
dc.subjectFibrillin-
dc.subjectGenes-
dc.subjectOral manifestations-
dc.subjectMarfan syndrome-
dc.subjectPeriodontitis/etiology-
dc.subjectConnective tissue diseases-
dc.titleSevere periodontitis in Marfan's syndrome: A case report-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1902/jop.2002.73.7.823-
dc.identifier.pmid12146542-
dc.identifier.scopuseid_2-s2.0-0036049115-
dc.identifier.volume73-
dc.identifier.issue7-
dc.identifier.spage823-
dc.identifier.epage826-

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