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Article: A controlled multicenter study of adjunctive use of tetracycline periodontal fibers in mandibular class II furcations with persistent bleeding

TitleA controlled multicenter study of adjunctive use of tetracycline periodontal fibers in mandibular class II furcations with persistent bleeding
Authors
KeywordsMaintenance care
Periodontitis
Tetracycline
Controlled clinical trial
Drug delivery
Furcation involvement
Human
Issue Date1998
Citation
Journal of Clinical Periodontology, 1998, v. 25, n. 9, p. 728-736 How to Cite?
AbstractThe aim of this randomized single-blind multicenter controlled clinical trial was to clinically evaluate the effectiveness of adjunctive local controlled drug delivery in the control of bleeding on probing in mandibular class II furcations during maintenance care. 127 patients presenting with a class II mandibular furcation with bleeding on probing were included in the study. They had been previously treated for periodontitis and were participating in supportive care programs in periodontal speciality practices. Treatments consisted of scaling and root planing with oral hygiene instructions (control) and scaling and root planing and oral hygiene combined with local controlled drug delivery with tetracycline fibers (test). The following outcomes were evaluated at baseline and 3 and 6 months after therapy at the furcation site: bleeding on controlled force probing (BOP), probing pocket depth (PD) and clinical attachment levels (CAL). Levels of oral hygiene and smoking status were also assessed. Both test and controls resulted in significant improvements of BOP and PD at 3 and 6 months. The test treatment, however, resulted in significantly better improvements: BOP decreased by 52% in the control group and by 70% in the test group at 3 months; at 6 months, however, the difference was no longer significant. The test treatment resulted in a 0.5 mm greater reduction of PD than the control at 3 months, the improvement was highly significant but its duration did not extend until the 6 months evaluation. No differences were observed in terms of changes in CAL. These data indicate that addition of tetracycline fibers to mechanical therapy alone resulted in improved control of periodontal parameters during periodontal maintenance of class II mandibular furcations. Short duration of the effect, however, requires further investigations to optimize conservative treatment of these challenging defects. © Munksgaard 1998.
Persistent Identifierhttp://hdl.handle.net/10722/230690
ISSN
2015 Impact Factor: 3.915
2015 SCImago Journal Rankings: 1.848

 

DC FieldValueLanguage
dc.contributor.authorTonetti, M. S.-
dc.contributor.authorCortellini, P.-
dc.contributor.authorCarnevale, G.-
dc.contributor.authorCattabriga, M.-
dc.contributor.authorDe Sanctis, M.-
dc.contributor.authorPini Prato, G. P.-
dc.date.accessioned2016-09-01T06:06:33Z-
dc.date.available2016-09-01T06:06:33Z-
dc.date.issued1998-
dc.identifier.citationJournal of Clinical Periodontology, 1998, v. 25, n. 9, p. 728-736-
dc.identifier.issn0303-6979-
dc.identifier.urihttp://hdl.handle.net/10722/230690-
dc.description.abstractThe aim of this randomized single-blind multicenter controlled clinical trial was to clinically evaluate the effectiveness of adjunctive local controlled drug delivery in the control of bleeding on probing in mandibular class II furcations during maintenance care. 127 patients presenting with a class II mandibular furcation with bleeding on probing were included in the study. They had been previously treated for periodontitis and were participating in supportive care programs in periodontal speciality practices. Treatments consisted of scaling and root planing with oral hygiene instructions (control) and scaling and root planing and oral hygiene combined with local controlled drug delivery with tetracycline fibers (test). The following outcomes were evaluated at baseline and 3 and 6 months after therapy at the furcation site: bleeding on controlled force probing (BOP), probing pocket depth (PD) and clinical attachment levels (CAL). Levels of oral hygiene and smoking status were also assessed. Both test and controls resulted in significant improvements of BOP and PD at 3 and 6 months. The test treatment, however, resulted in significantly better improvements: BOP decreased by 52% in the control group and by 70% in the test group at 3 months; at 6 months, however, the difference was no longer significant. The test treatment resulted in a 0.5 mm greater reduction of PD than the control at 3 months, the improvement was highly significant but its duration did not extend until the 6 months evaluation. No differences were observed in terms of changes in CAL. These data indicate that addition of tetracycline fibers to mechanical therapy alone resulted in improved control of periodontal parameters during periodontal maintenance of class II mandibular furcations. Short duration of the effect, however, requires further investigations to optimize conservative treatment of these challenging defects. © Munksgaard 1998.-
dc.languageeng-
dc.relation.ispartofJournal of Clinical Periodontology-
dc.subjectMaintenance care-
dc.subjectPeriodontitis-
dc.subjectTetracycline-
dc.subjectControlled clinical trial-
dc.subjectDrug delivery-
dc.subjectFurcation involvement-
dc.subjectHuman-
dc.titleA controlled multicenter study of adjunctive use of tetracycline periodontal fibers in mandibular class II furcations with persistent bleeding-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.pmid9763328-
dc.identifier.scopuseid_2-s2.0-0032160239-
dc.identifier.volume25-
dc.identifier.issue9-
dc.identifier.spage728-
dc.identifier.epage736-

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