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Article: No detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial.

TitleNo detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial.
Authors
Issue Date1995
Citation
Journal of clinical periodontology, 1995, v. 22, n. 9, p. 697-702 How to Cite?
AbstractThis controlled clinical trial evaluated the potential of fibrin glue as a biological carrier to locally deliver guided tissue regeneration (GTR) modulators, 2 controlateral, morphologically similar defects were selected in each of 11 patients and randomly assigned to the test (teflon membrane and fibrin glue) and the control treatment (teflon membrane alone). Outcomes were assessed at membrane removal as newly formed granulation tissue and at the 1-year follow-up in terms of changes in probing attachment level, probing pocket depth, recession of the gingival margin, probing bone levels and percentage of fill of the intrabony defects. Data confirmed that GTR treatment of deep intrabony defects results in clinically and statistically significant improvements of the clinical parameters. No significant differences, however, were evidenced between the test and the control treatments. It is suggested that, since fibrin glue did not show detrimental effects on GTR, it could be applied as a biological carrier for the delivery of GTR enhancers into the surgical wound.
Persistent Identifierhttp://hdl.handle.net/10722/230667
ISSN
2015 Impact Factor: 3.915
2015 SCImago Journal Rankings: 1.848

 

DC FieldValueLanguage
dc.contributor.authorCortellini, P.-
dc.contributor.authorPini Prato, G. P.-
dc.contributor.authorTonetti, M. S.-
dc.date.accessioned2016-09-01T06:06:30Z-
dc.date.available2016-09-01T06:06:30Z-
dc.date.issued1995-
dc.identifier.citationJournal of clinical periodontology, 1995, v. 22, n. 9, p. 697-702-
dc.identifier.issn0303-6979-
dc.identifier.urihttp://hdl.handle.net/10722/230667-
dc.description.abstractThis controlled clinical trial evaluated the potential of fibrin glue as a biological carrier to locally deliver guided tissue regeneration (GTR) modulators, 2 controlateral, morphologically similar defects were selected in each of 11 patients and randomly assigned to the test (teflon membrane and fibrin glue) and the control treatment (teflon membrane alone). Outcomes were assessed at membrane removal as newly formed granulation tissue and at the 1-year follow-up in terms of changes in probing attachment level, probing pocket depth, recession of the gingival margin, probing bone levels and percentage of fill of the intrabony defects. Data confirmed that GTR treatment of deep intrabony defects results in clinically and statistically significant improvements of the clinical parameters. No significant differences, however, were evidenced between the test and the control treatments. It is suggested that, since fibrin glue did not show detrimental effects on GTR, it could be applied as a biological carrier for the delivery of GTR enhancers into the surgical wound.-
dc.languageeng-
dc.relation.ispartofJournal of clinical periodontology-
dc.titleNo detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial.-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.pmid7593700-
dc.identifier.scopuseid_2-s2.0-0029376966-
dc.identifier.volume22-
dc.identifier.issue9-
dc.identifier.spage697-
dc.identifier.epage702-

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