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- Scopus: eid_2-s2.0-0029376966
- PMID: 7593700
- WOS: WOS:A1995RQ39100007
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Article: No detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial.
Title | No detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial. |
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Authors | |
Keywords | biological carriers clinical trial fibrin guided tissue regeneration intrabony defects wound healing |
Issue Date | 1995 |
Citation | Journal of clinical periodontology, 1995, v. 22, n. 9, p. 697-702 How to Cite? |
Abstract | This controlled clinical trial evaluated the potential of fibrin glue as a biological carrier to locally deliver guided tissue regeneration (GTR) modulators, 2 controlateral, morphologically similar defects were selected in each of 11 patients and randomly assigned to the test (teflon membrane and fibrin glue) and the control treatment (teflon membrane alone). Outcomes were assessed at membrane removal as newly formed granulation tissue and at the 1-year follow-up in terms of changes in probing attachment level, probing pocket depth, recession of the gingival margin, probing bone levels and percentage of fill of the intrabony defects. Data confirmed that GTR treatment of deep intrabony defects results in clinically and statistically significant improvements of the clinical parameters. No significant differences, however, were evidenced between the test and the control treatments. It is suggested that, since fibrin glue did not show detrimental effects on GTR, it could be applied as a biological carrier for the delivery of GTR enhancers into the surgical wound. |
Persistent Identifier | http://hdl.handle.net/10722/230667 |
ISSN | 2023 Impact Factor: 5.8 2023 SCImago Journal Rankings: 2.249 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Cortellini, P. | - |
dc.contributor.author | Pini Prato, G. P. | - |
dc.contributor.author | Tonetti, M. S. | - |
dc.date.accessioned | 2016-09-01T06:06:30Z | - |
dc.date.available | 2016-09-01T06:06:30Z | - |
dc.date.issued | 1995 | - |
dc.identifier.citation | Journal of clinical periodontology, 1995, v. 22, n. 9, p. 697-702 | - |
dc.identifier.issn | 0303-6979 | - |
dc.identifier.uri | http://hdl.handle.net/10722/230667 | - |
dc.description.abstract | This controlled clinical trial evaluated the potential of fibrin glue as a biological carrier to locally deliver guided tissue regeneration (GTR) modulators, 2 controlateral, morphologically similar defects were selected in each of 11 patients and randomly assigned to the test (teflon membrane and fibrin glue) and the control treatment (teflon membrane alone). Outcomes were assessed at membrane removal as newly formed granulation tissue and at the 1-year follow-up in terms of changes in probing attachment level, probing pocket depth, recession of the gingival margin, probing bone levels and percentage of fill of the intrabony defects. Data confirmed that GTR treatment of deep intrabony defects results in clinically and statistically significant improvements of the clinical parameters. No significant differences, however, were evidenced between the test and the control treatments. It is suggested that, since fibrin glue did not show detrimental effects on GTR, it could be applied as a biological carrier for the delivery of GTR enhancers into the surgical wound. | - |
dc.language | eng | - |
dc.relation.ispartof | Journal of clinical periodontology | - |
dc.subject | biological carriers | - |
dc.subject | clinical trial | - |
dc.subject | fibrin | - |
dc.subject | guided tissue regeneration | - |
dc.subject | intrabony defects | - |
dc.subject | wound healing | - |
dc.title | No detrimental effect of fibrin glue on the regeneration of intrabony defects. A controlled clinical trial. | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.pmid | 7593700 | - |
dc.identifier.scopus | eid_2-s2.0-0029376966 | - |
dc.identifier.volume | 22 | - |
dc.identifier.issue | 9 | - |
dc.identifier.spage | 697 | - |
dc.identifier.epage | 702 | - |
dc.identifier.isi | WOS:A1995RQ39100007 | - |
dc.identifier.issnl | 0303-6979 | - |