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Article: Ultrastructural calcification of glomerular immune complexes

TitleUltrastructural calcification of glomerular immune complexes
Authors
KeywordsGranulomatous inflammation
Issue Date1996
Citation
Modern Pathology, 1996, v. 9, n. 1, p. 36-40 How to Cite?
AbstractWe report a previously undescribed ultrastructural calcification of glomerular immune complex depositions in a patient with lupus nephritis. Such processes give rise to a distinctive ultrastructural calcified microspheriol in electron-dense immune deposits, and were associated with hypercalcemia and nephrocalcinosis. The cause of hypercalcemia in this patient was uncertain, but related to a granulomatous inflammation and abscess of the breast. Whereas ultrastructural microcalcification was associated with hypercalcemia, its distribution in the segmental glomerular lesions suggests that an inflammatory process was contributory. The clinical follow-up indicates that the microcalcifications of immune complexes have not affected the outcome of nephritis and renal function.
Persistent Identifierhttp://hdl.handle.net/10722/228484
ISSN
2015 Impact Factor: 5.485
2015 SCImago Journal Rankings: 2.803

 

DC FieldValueLanguage
dc.contributor.authorLai, F. Mac Moune-
dc.contributor.authorTo, K. F.-
dc.contributor.authorWang, Angela-
dc.contributor.authorChoi, P. C L-
dc.contributor.authorCheng, J. S K-
dc.contributor.authorChew, E. C.-
dc.date.accessioned2016-08-13T08:02:32Z-
dc.date.available2016-08-13T08:02:32Z-
dc.date.issued1996-
dc.identifier.citationModern Pathology, 1996, v. 9, n. 1, p. 36-40-
dc.identifier.issn0893-3952-
dc.identifier.urihttp://hdl.handle.net/10722/228484-
dc.description.abstractWe report a previously undescribed ultrastructural calcification of glomerular immune complex depositions in a patient with lupus nephritis. Such processes give rise to a distinctive ultrastructural calcified microspheriol in electron-dense immune deposits, and were associated with hypercalcemia and nephrocalcinosis. The cause of hypercalcemia in this patient was uncertain, but related to a granulomatous inflammation and abscess of the breast. Whereas ultrastructural microcalcification was associated with hypercalcemia, its distribution in the segmental glomerular lesions suggests that an inflammatory process was contributory. The clinical follow-up indicates that the microcalcifications of immune complexes have not affected the outcome of nephritis and renal function.-
dc.languageeng-
dc.relation.ispartofModern Pathology-
dc.subjectGranulomatous inflammation-
dc.titleUltrastructural calcification of glomerular immune complexes-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.pmid8821954-
dc.identifier.scopuseid_2-s2.0-9044233258-
dc.identifier.volume9-
dc.identifier.issue1-
dc.identifier.spage36-
dc.identifier.epage40-

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