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Article: Consequences of Chronic Inflammation in Peritoneal Dialysis

TitleConsequences of Chronic Inflammation in Peritoneal Dialysis
Authors
KeywordsCardiovascular
Issue Date2011
Citation
Seminars in Nephrology, 2011, v. 31, n. 2, p. 159-171 How to Cite?
AbstractThe mortality of end-stage renal disease (ESRD) patients, including those receiving long-term peritoneal dialysis (PD), has remained unacceptably high owing to the prevalence of cardiovascular disease. It is well recognized that both traditional Framingham risk factors and kidney disease-related risk factors may contribute to the high prevalence of cardiovascular disease in these patients. Of the different risk factors, chronic inflammation frequently is observed in long-term PD patients. The causes of inflammation are usually complex and multifactorial, involving both dialysis-related and dialysis-unrelated factors. Inflammation is strongly associated with cardiovascular disease and malnutrition, and has been shown consistently to be a powerful predictor of mortality and adverse cardiovascular outcomes in PD patients. In this article we review the prevalence and potential causes of chronic inflammation in PD patients. More importantly, we provide emerging evidence that shows the serious consequences of chronic systemic inflammation in PD patients and the important contribution of inflammation to adverse clinical outcomes. © 2011 Elsevier Inc.
Persistent Identifierhttp://hdl.handle.net/10722/228462
ISSN
2015 Impact Factor: 3.773
2015 SCImago Journal Rankings: 1.974

 

DC FieldValueLanguage
dc.contributor.authorWang, Angela Yee Moon-
dc.date.accessioned2016-08-13T08:02:28Z-
dc.date.available2016-08-13T08:02:28Z-
dc.date.issued2011-
dc.identifier.citationSeminars in Nephrology, 2011, v. 31, n. 2, p. 159-171-
dc.identifier.issn0270-9295-
dc.identifier.urihttp://hdl.handle.net/10722/228462-
dc.description.abstractThe mortality of end-stage renal disease (ESRD) patients, including those receiving long-term peritoneal dialysis (PD), has remained unacceptably high owing to the prevalence of cardiovascular disease. It is well recognized that both traditional Framingham risk factors and kidney disease-related risk factors may contribute to the high prevalence of cardiovascular disease in these patients. Of the different risk factors, chronic inflammation frequently is observed in long-term PD patients. The causes of inflammation are usually complex and multifactorial, involving both dialysis-related and dialysis-unrelated factors. Inflammation is strongly associated with cardiovascular disease and malnutrition, and has been shown consistently to be a powerful predictor of mortality and adverse cardiovascular outcomes in PD patients. In this article we review the prevalence and potential causes of chronic inflammation in PD patients. More importantly, we provide emerging evidence that shows the serious consequences of chronic systemic inflammation in PD patients and the important contribution of inflammation to adverse clinical outcomes. © 2011 Elsevier Inc.-
dc.languageeng-
dc.relation.ispartofSeminars in Nephrology-
dc.subjectCardiovascular-
dc.titleConsequences of Chronic Inflammation in Peritoneal Dialysis-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.semnephrol.2011.01.005-
dc.identifier.pmid21439430-
dc.identifier.scopuseid_2-s2.0-79952778908-
dc.identifier.volume31-
dc.identifier.issue2-
dc.identifier.spage159-
dc.identifier.epage171-

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