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Article: Selective internal radiation therapy by yttrium-90 microspheres for hepatocellular carcinoma after renal transplantation

TitleSelective internal radiation therapy by yttrium-90 microspheres for hepatocellular carcinoma after renal transplantation
Authors
KeywordsHepatocellular carcinoma
Issue Date2001
Citation
Clinical Transplantation, 2001, v. 15, n. 4, p. 284-288 How to Cite?
AbstractWe report a HBsAg-positive patient who developed hepatocellular carcinoma (HCC) 7 years after cadaveric kidney transplantation. The tumor was unresectable because of coexisting cirrhosis. Selective internal radiation (SIR) therapy, a novel therapy with the technique recently perfected, was used. Yttrium-90 microspheres were given via an angiographic catheter under fluoroscopy guidance. Serum alpha-fetal protein (AFP) was normalized within 2 wk. A follow-up abdominal CT scan revealed significant necrosis of the tumor and compensatory hypertrophy of non-diseased liver. The treatment was well tolerated except for transient liver function deterioration. The patient enjoyed 15 months of symptom-free survival before she died of liver failure. Practical aspects and potential applications of SIR therapy in this group of patients are discussed.
Persistent Identifierhttp://hdl.handle.net/10722/228440
ISSN
2015 Impact Factor: 1.844
2015 SCImago Journal Rankings: 0.821

 

DC FieldValueLanguage
dc.contributor.authorSzeto, Cheuk Chun-
dc.contributor.authorWong, Teresa Yuk Hwa-
dc.contributor.authorLeung, Chi Bon-
dc.contributor.authorLeung, Thomas Wai Tong-
dc.contributor.authorWang, Angela Yee Moon-
dc.contributor.authorLui, Siu Fai-
dc.contributor.authorLi, Philip Kam Tao-
dc.date.accessioned2016-08-13T08:02:25Z-
dc.date.available2016-08-13T08:02:25Z-
dc.date.issued2001-
dc.identifier.citationClinical Transplantation, 2001, v. 15, n. 4, p. 284-288-
dc.identifier.issn0902-0063-
dc.identifier.urihttp://hdl.handle.net/10722/228440-
dc.description.abstractWe report a HBsAg-positive patient who developed hepatocellular carcinoma (HCC) 7 years after cadaveric kidney transplantation. The tumor was unresectable because of coexisting cirrhosis. Selective internal radiation (SIR) therapy, a novel therapy with the technique recently perfected, was used. Yttrium-90 microspheres were given via an angiographic catheter under fluoroscopy guidance. Serum alpha-fetal protein (AFP) was normalized within 2 wk. A follow-up abdominal CT scan revealed significant necrosis of the tumor and compensatory hypertrophy of non-diseased liver. The treatment was well tolerated except for transient liver function deterioration. The patient enjoyed 15 months of symptom-free survival before she died of liver failure. Practical aspects and potential applications of SIR therapy in this group of patients are discussed.-
dc.languageeng-
dc.relation.ispartofClinical Transplantation-
dc.subjectHepatocellular carcinoma-
dc.titleSelective internal radiation therapy by yttrium-90 microspheres for hepatocellular carcinoma after renal transplantation-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1034/j.1399-0012.2001.150411.x-
dc.identifier.pmid11683824-
dc.identifier.scopuseid_2-s2.0-0034898428-
dc.identifier.volume15-
dc.identifier.issue4-
dc.identifier.spage284-
dc.identifier.epage288-

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