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- Publisher Website: 10.1097/ICB.0000000000000228
- Scopus: eid_2-s2.0-84962731845
- PMID: 26444523
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Article: Pimasertib and Serous Retinal Detachments
Title | Pimasertib and Serous Retinal Detachments |
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Authors | |
Keywords | MEK 1 and 2 |
Issue Date | 2016 |
Citation | Retinal Cases and Brief Reports, 2016, v. 10, n. 2, p. 191-196 How to Cite? |
Abstract | © by Ophthalmic Communications Society, Inc.Purpose: To report a case of multifocal serous retinal detachments associated with pimasertib. Methods: The authors report a 26-year-old patient who developed bilateral multifocal serous retinal detachments appearing 2 days after starting pimasertib (as part of a clinical trial investigating its use in low-grade metastatic ovarian cancer) and rapidly resolving 3 days after stopping it. Conclusion: The mechanism of MEK inhibitor induced visual toxicity remains unclear. The pathophysiology of multifocal serous retinal detachments as a complication of pimasertib is still poorly understood. Copyringht |
Persistent Identifier | http://hdl.handle.net/10722/228242 |
ISSN | 2023 SCImago Journal Rankings: 0.402 |
PubMed Central ID |
DC Field | Value | Language |
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dc.contributor.author | Alali, Alaa | - |
dc.contributor.author | Bushehri, Ahmad | - |
dc.contributor.author | Park, Jonathan C. | - |
dc.contributor.author | Krema, Hatem | - |
dc.contributor.author | Lam, Wai Ching | - |
dc.date.accessioned | 2016-08-01T06:45:33Z | - |
dc.date.available | 2016-08-01T06:45:33Z | - |
dc.date.issued | 2016 | - |
dc.identifier.citation | Retinal Cases and Brief Reports, 2016, v. 10, n. 2, p. 191-196 | - |
dc.identifier.issn | 1935-1089 | - |
dc.identifier.uri | http://hdl.handle.net/10722/228242 | - |
dc.description.abstract | © by Ophthalmic Communications Society, Inc.Purpose: To report a case of multifocal serous retinal detachments associated with pimasertib. Methods: The authors report a 26-year-old patient who developed bilateral multifocal serous retinal detachments appearing 2 days after starting pimasertib (as part of a clinical trial investigating its use in low-grade metastatic ovarian cancer) and rapidly resolving 3 days after stopping it. Conclusion: The mechanism of MEK inhibitor induced visual toxicity remains unclear. The pathophysiology of multifocal serous retinal detachments as a complication of pimasertib is still poorly understood. Copyringht | - |
dc.language | eng | - |
dc.relation.ispartof | Retinal Cases and Brief Reports | - |
dc.subject | MEK 1 and 2 | - |
dc.title | Pimasertib and Serous Retinal Detachments | - |
dc.type | Article | - |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.1097/ICB.0000000000000228 | - |
dc.identifier.pmid | 26444523 | - |
dc.identifier.pmcid | PMC4890820 | - |
dc.identifier.scopus | eid_2-s2.0-84962731845 | - |
dc.identifier.hkuros | 272454 | - |
dc.identifier.volume | 10 | - |
dc.identifier.issue | 2 | - |
dc.identifier.spage | 191 | - |
dc.identifier.epage | 196 | - |
dc.identifier.eissn | 1937-1578 | - |
dc.identifier.issnl | 1935-1089 | - |