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Article: A randomized controlled trial to investigate the impact of a low glycemic index (GI) diet on body mass index in obese adolescents

TitleA randomized controlled trial to investigate the impact of a low glycemic index (GI) diet on body mass index in obese adolescents
Authors
KeywordsAdolescents
Issue Date2014
Citation
BMC Public Health, 2014, v. 14, n. 1 How to Cite?
AbstractBackground: The role of a low glycemic index (GI) diet in the management of adolescent obesity remains controversial. In this study, we aim to evaluate the impact of low GI diet versus a conventional Chinese diet on the body mass index (BMI) and other obesity indices of obese adolescents. Methods. Obese adolescents aged 15-18 years were identified from population-recruited, territory-wide surveys. Obesity was defined as BMI ≥95th percentile of Hong Kong local age- and sex-specific references. Eligible subjects were randomized to either an intervention with low GI diet (consisting of 45-50% carbohydrate, 30-35% fat and 15-20% protein) or conventional Chinese diet as control (consisting of 55-60% carbohydrate, 25-30% fat and 10-15% protein). We used random intercept mixed effects model to compare the differential changes across the time points from baseline to month 6 between the 2 groups. Results: 104 obese adolescents were recruited (52 in low GI group and 52 in control group; 43.3% boys). Mean age was 16.7 ± 1.0 years and 16.8 ±1.0 years in low GI and control group respectively. 58.7% subjects completed the study at 6 months (65.4% in low GI group and 51.9% in control group). After adjustment for age and sex, subjects in the low GI group had a significantly greater reduction in obesity indices including BMI, body weight and waist circumference (WC) compared to subjects in the control group (all p <0.05). After further adjustment for physical activity levels, WC was found to be significantly lower in the low GI group compared to the conventional group (p = 0.018). Conclusion: Low GI diet in the context of a comprehensive lifestyle modification program may be an alternative to conventional diet in the management of obese adolescents. Trial registration number. ClinicalTrials.gov Ref. No: NCT01278563. © 2014 Kong et al.; licensee BioMed Central Ltd.
Persistent Identifierhttp://hdl.handle.net/10722/228183

 

DC FieldValueLanguage
dc.contributor.authorKong, Alice Ps-
dc.contributor.authorChoi, Kai Chow-
dc.contributor.authorChan, Ruth Sm-
dc.contributor.authorLok, Kris-
dc.contributor.authorOzaki, Risa-
dc.contributor.authorLi, Albert M.-
dc.contributor.authorHo, Chung Shun-
dc.contributor.authorChan, Michael Hm-
dc.contributor.authorSea, Mandy-
dc.contributor.authorHenry, C. Jeyakumar-
dc.contributor.authorChan, Juliana Cn-
dc.contributor.authorWoo, Jean-
dc.date.accessioned2016-08-01T06:45:24Z-
dc.date.available2016-08-01T06:45:24Z-
dc.date.issued2014-
dc.identifier.citationBMC Public Health, 2014, v. 14, n. 1-
dc.identifier.urihttp://hdl.handle.net/10722/228183-
dc.description.abstractBackground: The role of a low glycemic index (GI) diet in the management of adolescent obesity remains controversial. In this study, we aim to evaluate the impact of low GI diet versus a conventional Chinese diet on the body mass index (BMI) and other obesity indices of obese adolescents. Methods. Obese adolescents aged 15-18 years were identified from population-recruited, territory-wide surveys. Obesity was defined as BMI ≥95th percentile of Hong Kong local age- and sex-specific references. Eligible subjects were randomized to either an intervention with low GI diet (consisting of 45-50% carbohydrate, 30-35% fat and 15-20% protein) or conventional Chinese diet as control (consisting of 55-60% carbohydrate, 25-30% fat and 10-15% protein). We used random intercept mixed effects model to compare the differential changes across the time points from baseline to month 6 between the 2 groups. Results: 104 obese adolescents were recruited (52 in low GI group and 52 in control group; 43.3% boys). Mean age was 16.7 ± 1.0 years and 16.8 ±1.0 years in low GI and control group respectively. 58.7% subjects completed the study at 6 months (65.4% in low GI group and 51.9% in control group). After adjustment for age and sex, subjects in the low GI group had a significantly greater reduction in obesity indices including BMI, body weight and waist circumference (WC) compared to subjects in the control group (all p <0.05). After further adjustment for physical activity levels, WC was found to be significantly lower in the low GI group compared to the conventional group (p = 0.018). Conclusion: Low GI diet in the context of a comprehensive lifestyle modification program may be an alternative to conventional diet in the management of obese adolescents. Trial registration number. ClinicalTrials.gov Ref. No: NCT01278563. © 2014 Kong et al.; licensee BioMed Central Ltd.-
dc.languageeng-
dc.relation.ispartofBMC Public Health-
dc.subjectAdolescents-
dc.titleA randomized controlled trial to investigate the impact of a low glycemic index (GI) diet on body mass index in obese adolescents-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1186/1471-2458-14-180-
dc.identifier.pmid24552366-
dc.identifier.scopuseid_2-s2.0-84897605807-
dc.identifier.volume14-
dc.identifier.issue1-
dc.identifier.spagenull-
dc.identifier.epagenull-
dc.identifier.eissn1471-2458-

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