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- Publisher Website: 10.1136/bjo.85.10.1171
- Scopus: eid_2-s2.0-0034809970
- PMID: 11567959
- WOS: WOS:000171394600008
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Article: Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin
Title | Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin |
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Authors | |
Issue Date | 2001 |
Citation | British Journal of Ophthalmology, 2001, v. 85, n. 10, p. 1171-1173 How to Cite? |
Abstract | Aim - To assess the ocular effect of interferon alfa 2b prescribed with ribavirin in patients undergoing therapy for chronic hepatitis C. Methods - 19 Patients with chronic hepatitis C who satisfied the follow up criteria were assessed for ocular complications using slit lamp biomicroscopy and indirect ophthalmoscopy before, during, and after the treatment at regular intervals. Results - 8/19 Patients, while on treatment, developed an asymptomatic retinopathy. Among these 3/8 were relapsers and 5/9 were non-responders to interferon monotherapy. All retinal changes faded, often while the patients continued the therapy. There was no significant association in occurrence of retinopathy with haematological and/or biochemical changes. Conclusion - Retinopathy was more common in interferon monotherapy non-responders than relapsers when treated with interferon alfa 2b with the addition of ribavirin. The changes were transient, disappearing while the patients were still being treated. |
Persistent Identifier | http://hdl.handle.net/10722/228010 |
ISSN | 2023 Impact Factor: 3.7 2023 SCImago Journal Rankings: 1.862 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Jain, K. | - |
dc.contributor.author | Lam, W. C. | - |
dc.contributor.author | Waheeb, S. | - |
dc.contributor.author | Thai, Q. | - |
dc.contributor.author | Heathcote, J. | - |
dc.date.accessioned | 2016-08-01T06:44:58Z | - |
dc.date.available | 2016-08-01T06:44:58Z | - |
dc.date.issued | 2001 | - |
dc.identifier.citation | British Journal of Ophthalmology, 2001, v. 85, n. 10, p. 1171-1173 | - |
dc.identifier.issn | 0007-1161 | - |
dc.identifier.uri | http://hdl.handle.net/10722/228010 | - |
dc.description.abstract | Aim - To assess the ocular effect of interferon alfa 2b prescribed with ribavirin in patients undergoing therapy for chronic hepatitis C. Methods - 19 Patients with chronic hepatitis C who satisfied the follow up criteria were assessed for ocular complications using slit lamp biomicroscopy and indirect ophthalmoscopy before, during, and after the treatment at regular intervals. Results - 8/19 Patients, while on treatment, developed an asymptomatic retinopathy. Among these 3/8 were relapsers and 5/9 were non-responders to interferon monotherapy. All retinal changes faded, often while the patients continued the therapy. There was no significant association in occurrence of retinopathy with haematological and/or biochemical changes. Conclusion - Retinopathy was more common in interferon monotherapy non-responders than relapsers when treated with interferon alfa 2b with the addition of ribavirin. The changes were transient, disappearing while the patients were still being treated. | - |
dc.language | eng | - |
dc.relation.ispartof | British Journal of Ophthalmology | - |
dc.title | Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1136/bjo.85.10.1171 | - |
dc.identifier.pmid | 11567959 | - |
dc.identifier.scopus | eid_2-s2.0-0034809970 | - |
dc.identifier.volume | 85 | - |
dc.identifier.issue | 10 | - |
dc.identifier.spage | 1171 | - |
dc.identifier.epage | 1173 | - |
dc.identifier.isi | WOS:000171394600008 | - |
dc.identifier.issnl | 0007-1161 | - |