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Article: Retinopathy in chronic hepatitis C patients during interferon treatment with ribavirin

TitleRetinopathy in chronic hepatitis C patients during interferon treatment with ribavirin
Authors
Issue Date2001
Citation
British Journal of Ophthalmology, 2001, v. 85, n. 10, p. 1171-1173 How to Cite?
AbstractAim - To assess the ocular effect of interferon alfa 2b prescribed with ribavirin in patients undergoing therapy for chronic hepatitis C. Methods - 19 Patients with chronic hepatitis C who satisfied the follow up criteria were assessed for ocular complications using slit lamp biomicroscopy and indirect ophthalmoscopy before, during, and after the treatment at regular intervals. Results - 8/19 Patients, while on treatment, developed an asymptomatic retinopathy. Among these 3/8 were relapsers and 5/9 were non-responders to interferon monotherapy. All retinal changes faded, often while the patients continued the therapy. There was no significant association in occurrence of retinopathy with haematological and/or biochemical changes. Conclusion - Retinopathy was more common in interferon monotherapy non-responders than relapsers when treated with interferon alfa 2b with the addition of ribavirin. The changes were transient, disappearing while the patients were still being treated.
Persistent Identifierhttp://hdl.handle.net/10722/228010
ISSN
2015 Impact Factor: 3.036
2015 SCImago Journal Rankings: 1.873

 

DC FieldValueLanguage
dc.contributor.authorJain, K.-
dc.contributor.authorLam, W. C.-
dc.contributor.authorWaheeb, S.-
dc.contributor.authorThai, Q.-
dc.contributor.authorHeathcote, J.-
dc.date.accessioned2016-08-01T06:44:58Z-
dc.date.available2016-08-01T06:44:58Z-
dc.date.issued2001-
dc.identifier.citationBritish Journal of Ophthalmology, 2001, v. 85, n. 10, p. 1171-1173-
dc.identifier.issn0007-1161-
dc.identifier.urihttp://hdl.handle.net/10722/228010-
dc.description.abstractAim - To assess the ocular effect of interferon alfa 2b prescribed with ribavirin in patients undergoing therapy for chronic hepatitis C. Methods - 19 Patients with chronic hepatitis C who satisfied the follow up criteria were assessed for ocular complications using slit lamp biomicroscopy and indirect ophthalmoscopy before, during, and after the treatment at regular intervals. Results - 8/19 Patients, while on treatment, developed an asymptomatic retinopathy. Among these 3/8 were relapsers and 5/9 were non-responders to interferon monotherapy. All retinal changes faded, often while the patients continued the therapy. There was no significant association in occurrence of retinopathy with haematological and/or biochemical changes. Conclusion - Retinopathy was more common in interferon monotherapy non-responders than relapsers when treated with interferon alfa 2b with the addition of ribavirin. The changes were transient, disappearing while the patients were still being treated.-
dc.languageeng-
dc.relation.ispartofBritish Journal of Ophthalmology-
dc.titleRetinopathy in chronic hepatitis C patients during interferon treatment with ribavirin-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1136/bjo.85.10.1171-
dc.identifier.pmid11567959-
dc.identifier.scopuseid_2-s2.0-0034809970-
dc.identifier.volume85-
dc.identifier.issue10-
dc.identifier.spage1171-
dc.identifier.epage1173-

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