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Article: Biomimetic synthesis of apatite - polyelectrolyte complex (chitosan - phosphorylated chitosan) hydrogel as an osteoblast carrier

TitleBiomimetic synthesis of apatite - polyelectrolyte complex (chitosan - phosphorylated chitosan) hydrogel as an osteoblast carrier
Authors
KeywordsBiomineralization
Chitosan (CS)
Osteoblast
Phosphorylated Chitosan
Polyelectrolyte Complex (PEX)
Issue Date2005
PublisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net
Citation
Key Engineering Materials, 2005, v. 288-289, p. 75-78 How to Cite?
AbstractA novel three-dimensional scaffold of hydroxyapatite(HA)-polyelectrolyte complex (PEC) composite hydrogel was synthesized by a biomimetic method. PEC hydrogel was formed from equal volumes of 1% phosphorylated chitosan in water and 1% chitosan in 1% acetic acid solution. This PEC hydrogel was soaked in saturated Ca(OH)2 solution for 4 d and then in accelerated calcification solution (ACS) for 7 d, both at 37 oC. The PEC hydrogel was a nano-composite material with multiple levels of hierarchical porosity; hydroxyapatite (HA) crystals nucleated and grew on the fiber surfaces of the hydrogel; Rat osteoblasts were then seeded in this three-dimensional scaffold of HA-PEC composite hydrogel, the three-dimensional scaffold of HA-PEC hydrogel revealed excellent biocompatibility.
Persistent Identifierhttp://hdl.handle.net/10722/224090
ISSN
2005 Impact Factor: 0.224
2015 SCImago Journal Rankings: 0.173

 

DC FieldValueLanguage
dc.contributor.authorLi, QL-
dc.contributor.authorChen, ZQ-
dc.contributor.authorOu, GM-
dc.contributor.authorLiu, L-
dc.contributor.authorJiang, HB-
dc.contributor.authorZeng, Q-
dc.contributor.authorLi, G-
dc.contributor.authorHe, G-
dc.contributor.authorMo, AC-
dc.contributor.authorDarvell, BW-
dc.date.accessioned2016-03-23T02:39:51Z-
dc.date.available2016-03-23T02:39:51Z-
dc.date.issued2005-
dc.identifier.citationKey Engineering Materials, 2005, v. 288-289, p. 75-78-
dc.identifier.issn1013-9826-
dc.identifier.urihttp://hdl.handle.net/10722/224090-
dc.description.abstractA novel three-dimensional scaffold of hydroxyapatite(HA)-polyelectrolyte complex (PEC) composite hydrogel was synthesized by a biomimetic method. PEC hydrogel was formed from equal volumes of 1% phosphorylated chitosan in water and 1% chitosan in 1% acetic acid solution. This PEC hydrogel was soaked in saturated Ca(OH)2 solution for 4 d and then in accelerated calcification solution (ACS) for 7 d, both at 37 oC. The PEC hydrogel was a nano-composite material with multiple levels of hierarchical porosity; hydroxyapatite (HA) crystals nucleated and grew on the fiber surfaces of the hydrogel; Rat osteoblasts were then seeded in this three-dimensional scaffold of HA-PEC composite hydrogel, the three-dimensional scaffold of HA-PEC hydrogel revealed excellent biocompatibility.-
dc.languageeng-
dc.publisherTrans Tech Publications Ltd. The Journal's web site is located at http://www.scientific.net-
dc.relation.ispartofKey Engineering Materials-
dc.subjectBiomineralization-
dc.subjectChitosan (CS)-
dc.subjectOsteoblast-
dc.subjectPhosphorylated Chitosan-
dc.subjectPolyelectrolyte Complex (PEX)-
dc.titleBiomimetic synthesis of apatite - polyelectrolyte complex (chitosan - phosphorylated chitosan) hydrogel as an osteoblast carrier-
dc.typeArticle-
dc.identifier.emailDarvell, BW: hrdubwd@hkucc.hku.hk-
dc.identifier.authorityDarvell, BW=rp00007-
dc.identifier.doi10.4028/www.scientific.net/KEM.288-289.75-
dc.identifier.hkuros97302-
dc.identifier.volume288-289-
dc.identifier.spage75-
dc.identifier.epage78-
dc.publisher.placeSwitzerland-

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