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Article: Induction of antibiotic production of freshwater fungi using mix-culture fermentation
Title | Induction of antibiotic production of freshwater fungi using mix-culture fermentation |
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Authors | |
Keywords | Anti-fungal Antibiotic induction technology Fermentation Tropical fungi |
Issue Date | 2003 |
Publisher | Fungal Diversity Press. The Journal's web site is located at http://www.fungaldiversity.org/fdp/jumble.php |
Citation | Fungal Diversity, 2003, v. 12, p. 45-51 How to Cite? |
Abstract | Antibiotic activities of culture filtrates from twenty filamentous fungi, isolated from wood submerged in tropical freshwater habitats, were tested against a pathogenic strain of Candida albicans. These taxa were fermented separately in liquid medium in pure culture, while another set was fermented with the addition of a fluconazole-sensitive strain of Candida albicans in mix-culture. Fermentation was performed using potato dextrose broth at 25°C for 28 days, with diffuse day light and 240 rpm agitation. Culture filtrates were tested against a fluconazole-sensitive and two fluconazole-resistant strains of C. albicans. Anti-fungal activities against strains of C. albicans were not exhibited by any culture filtrates obtained from pure culture fermentation. In mix-culture fermentation, the culture filtrates of an undescribed species of Chloridium and Sporoschisma mirabile produced anti-fungal activities against all three strains of C. albicans tested. |
Persistent Identifier | http://hdl.handle.net/10722/223478 |
ISSN | 2023 Impact Factor: 24.5 2023 SCImago Journal Rankings: 6.787 |
DC Field | Value | Language |
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dc.contributor.author | Ho, WH | - |
dc.contributor.author | To, PC | - |
dc.contributor.author | Hyde, KD | - |
dc.date.accessioned | 2016-02-29T08:59:13Z | - |
dc.date.available | 2016-02-29T08:59:13Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Fungal Diversity, 2003, v. 12, p. 45-51 | - |
dc.identifier.issn | 1560-2745 | - |
dc.identifier.uri | http://hdl.handle.net/10722/223478 | - |
dc.description.abstract | Antibiotic activities of culture filtrates from twenty filamentous fungi, isolated from wood submerged in tropical freshwater habitats, were tested against a pathogenic strain of Candida albicans. These taxa were fermented separately in liquid medium in pure culture, while another set was fermented with the addition of a fluconazole-sensitive strain of Candida albicans in mix-culture. Fermentation was performed using potato dextrose broth at 25°C for 28 days, with diffuse day light and 240 rpm agitation. Culture filtrates were tested against a fluconazole-sensitive and two fluconazole-resistant strains of C. albicans. Anti-fungal activities against strains of C. albicans were not exhibited by any culture filtrates obtained from pure culture fermentation. In mix-culture fermentation, the culture filtrates of an undescribed species of Chloridium and Sporoschisma mirabile produced anti-fungal activities against all three strains of C. albicans tested. | - |
dc.language | eng | - |
dc.publisher | Fungal Diversity Press. The Journal's web site is located at http://www.fungaldiversity.org/fdp/jumble.php | - |
dc.relation.ispartof | Fungal Diversity | - |
dc.subject | Anti-fungal | - |
dc.subject | Antibiotic induction technology | - |
dc.subject | Fermentation | - |
dc.subject | Tropical fungi | - |
dc.title | Induction of antibiotic production of freshwater fungi using mix-culture fermentation | - |
dc.type | Article | - |
dc.identifier.email | Hyde, KD: kdhyde@hkucc.hku.hk | - |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.scopus | eid_2-s2.0-4243108396 | - |
dc.identifier.hkuros | 76168 | - |
dc.identifier.volume | 12 | - |
dc.identifier.spage | 45 | - |
dc.identifier.epage | 51 | - |
dc.publisher.place | Hong Kong | - |
dc.identifier.issnl | 1560-2745 | - |