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Article: Randomized Controlled Trial Investigating the Effects of a Low–Glycemic Index Diet on Pregnancy Outcomes in Women at High Risk of Gestational Diabetes Mellitus: The GI Baby 3 Study

TitleRandomized Controlled Trial Investigating the Effects of a Low–Glycemic Index Diet on Pregnancy Outcomes in Women at High Risk of Gestational Diabetes Mellitus: The GI Baby 3 Study
Authors
Issue Date2016
PublisherAmerican Diabetes Association. The Journal's web site is located at http://diabetes.diabetesjournals.org/
Citation
Diabetes Care, 2016, v. 39 n. 1, p. 31-38 How to Cite?
AbstractOBJECTIVE: Dietary interventions can improve pregnancy outcomes in women with gestational diabetes mellitus (GDM). We compared the effect of a low-glycemic index (GI) versus a conventional high-fiber (HF) diet on pregnancy outcomes, birth weight z score, and maternal metabolic profile in women at high risk of GDM. RESEARCH DESIGN AND METHODS: One hundred thirty-nine women [mean (SD) age 34.7 (0.4) years and prepregnancy BMI 25.2 (0.5) kg/m(2)] were randomly assigned to a low-GI (LGI) diet (n = 72; target GI ∼50) or a high-fiber, moderate-GI (HF) diet (n = 67; target GI ∼60) at 14-20 weeks' gestation. Diet was assessed by 3-day food records and infant body composition by air-displacement plethysmography, and pregnancy outcomes were assessed from medical records. RESULTS: The LGI group achieved a lower GI than the HF group [mean (SD) 50 (5) vs. 58 (5); P < 0.001]. There were no differences in glycosylated hemoglobin, fructosamine, or lipids at 36 weeks or differences in birth weight [LGI 3.4 (0.4) kg vs. HF 3.4 (0.5) kg; P = 0.514], birth weight z score [LGI 0.31 (0.90) vs. HF 0.24 (1.07); P = 0.697], ponderal index [LGI 2.71 (0.22) vs. HF 2.69 (0.23) kg/m(3); P = 0.672], birth weight centile [LGI 46.2 (25.4) vs. HF 41.8 (25.6); P = 0.330], % fat mass [LGI 10 (4) vs. HF 10 (4); P = 0.789], or incidence of GDM. CONCLUSIONS: In intensively monitored women at risk for GDM, a low-GI diet and a healthy diet produce similar pregnancy outcomes.
Persistent Identifierhttp://hdl.handle.net/10722/223305
ISSN
2015 Impact Factor: 8.934
2015 SCImago Journal Rankings: 5.827

 

DC FieldValueLanguage
dc.contributor.authorMarkovic, TP-
dc.contributor.authorMuirhead, R-
dc.contributor.authorOvers, S-
dc.contributor.authorRoss, GP-
dc.contributor.authorLouie, CYJ-
dc.contributor.authorKizirian, N-
dc.contributor.authorDenyer, G-
dc.contributor.authorPetocz, P-
dc.contributor.authorHyett, J-
dc.contributor.authorBrand-Miller, JC-
dc.date.accessioned2016-02-23T01:56:44Z-
dc.date.available2016-02-23T01:56:44Z-
dc.date.issued2016-
dc.identifier.citationDiabetes Care, 2016, v. 39 n. 1, p. 31-38-
dc.identifier.issn0149-5992-
dc.identifier.urihttp://hdl.handle.net/10722/223305-
dc.description.abstractOBJECTIVE: Dietary interventions can improve pregnancy outcomes in women with gestational diabetes mellitus (GDM). We compared the effect of a low-glycemic index (GI) versus a conventional high-fiber (HF) diet on pregnancy outcomes, birth weight z score, and maternal metabolic profile in women at high risk of GDM. RESEARCH DESIGN AND METHODS: One hundred thirty-nine women [mean (SD) age 34.7 (0.4) years and prepregnancy BMI 25.2 (0.5) kg/m(2)] were randomly assigned to a low-GI (LGI) diet (n = 72; target GI ∼50) or a high-fiber, moderate-GI (HF) diet (n = 67; target GI ∼60) at 14-20 weeks' gestation. Diet was assessed by 3-day food records and infant body composition by air-displacement plethysmography, and pregnancy outcomes were assessed from medical records. RESULTS: The LGI group achieved a lower GI than the HF group [mean (SD) 50 (5) vs. 58 (5); P < 0.001]. There were no differences in glycosylated hemoglobin, fructosamine, or lipids at 36 weeks or differences in birth weight [LGI 3.4 (0.4) kg vs. HF 3.4 (0.5) kg; P = 0.514], birth weight z score [LGI 0.31 (0.90) vs. HF 0.24 (1.07); P = 0.697], ponderal index [LGI 2.71 (0.22) vs. HF 2.69 (0.23) kg/m(3); P = 0.672], birth weight centile [LGI 46.2 (25.4) vs. HF 41.8 (25.6); P = 0.330], % fat mass [LGI 10 (4) vs. HF 10 (4); P = 0.789], or incidence of GDM. CONCLUSIONS: In intensively monitored women at risk for GDM, a low-GI diet and a healthy diet produce similar pregnancy outcomes.-
dc.languageeng-
dc.publisherAmerican Diabetes Association. The Journal's web site is located at http://diabetes.diabetesjournals.org/-
dc.relation.ispartofDiabetes Care-
dc.rightsThis is an author-created, uncopyedited electronic version of an article accepted for publication in TITLE [Journal URL]. The American Diabetes Association (ADA), publisher of TITLE, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisher-authenticated version is available online at [URL]-
dc.titleRandomized Controlled Trial Investigating the Effects of a Low–Glycemic Index Diet on Pregnancy Outcomes in Women at High Risk of Gestational Diabetes Mellitus: The GI Baby 3 Study-
dc.typeArticle-
dc.identifier.emailLouie, CYJ: jimmyl@hku.hk-
dc.identifier.authorityLouie, CYJ=rp02118-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.2337/dc15-0572-
dc.identifier.pmid26185283-
dc.identifier.hkuros256869-
dc.identifier.volume39-
dc.identifier.issue1-
dc.identifier.spage31-
dc.identifier.epage38-
dc.publisher.placeUnited States-

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