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Article: Association of Hemoglobin A1c Levels With Cardiovascular Disease and Mortality in Chinese Patients With Diabetes

TitleAssociation of Hemoglobin A1c Levels With Cardiovascular Disease and Mortality in Chinese Patients With Diabetes
Authors
Issue Date2016
Citation
Journal of the American College of Cardiology, 2016, v. 67 n. 4, p. 456-458 How to Cite?
AbstractAmong diabetic patients, hemoglobin A1c (HbA1c) is an important indicator of glycemic control and, together with blood pressure and cholesterol, is an indicator for risk of complications, including cardiovascular disease (CVD) and mortality. At present, there is no universal consensus on the optimal HbA1c level. Despite this, most international guidelines include a recommended HbA1c target range or level as a treatment goal. Several studies have identified a J-shaped curvilinear relationship between HbA1c and CVD incidence and all-cause mortality, but such a relationship has not yet been confirmed in a Chinese population. There are substantial differences in disease risks across racial and ethnic groups due to genetic and environmental factors including life-style and health behaviors, and thus, previous results from Western studies may not be transferable to a Chinese population. We sought to examine the association among mean HbA1c, CVD events, and mortality among Chinese primary care patients with type 2 diabetes mellitus (T2DM) in Hong Kong.
Persistent Identifierhttp://hdl.handle.net/10722/223216
ISSN
2015 Impact Factor: 17.759
2015 SCImago Journal Rankings: 10.097
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWan, YF-
dc.contributor.authorFung, SCC-
dc.contributor.authorWong, CKH-
dc.contributor.authorChin, WY-
dc.contributor.authorLam, CLK-
dc.date.accessioned2016-02-23T01:55:38Z-
dc.date.available2016-02-23T01:55:38Z-
dc.date.issued2016-
dc.identifier.citationJournal of the American College of Cardiology, 2016, v. 67 n. 4, p. 456-458-
dc.identifier.issn0735-1097-
dc.identifier.urihttp://hdl.handle.net/10722/223216-
dc.description.abstractAmong diabetic patients, hemoglobin A1c (HbA1c) is an important indicator of glycemic control and, together with blood pressure and cholesterol, is an indicator for risk of complications, including cardiovascular disease (CVD) and mortality. At present, there is no universal consensus on the optimal HbA1c level. Despite this, most international guidelines include a recommended HbA1c target range or level as a treatment goal. Several studies have identified a J-shaped curvilinear relationship between HbA1c and CVD incidence and all-cause mortality, but such a relationship has not yet been confirmed in a Chinese population. There are substantial differences in disease risks across racial and ethnic groups due to genetic and environmental factors including life-style and health behaviors, and thus, previous results from Western studies may not be transferable to a Chinese population. We sought to examine the association among mean HbA1c, CVD events, and mortality among Chinese primary care patients with type 2 diabetes mellitus (T2DM) in Hong Kong.-
dc.languageeng-
dc.relation.ispartofJournal of the American College of Cardiology-
dc.titleAssociation of Hemoglobin A1c Levels With Cardiovascular Disease and Mortality in Chinese Patients With Diabetes-
dc.typeArticle-
dc.identifier.emailWan, YF: yfwan@hku.hk-
dc.identifier.emailFung, SCC: cfsc@hku.hk-
dc.identifier.emailWong, CKH: carlosho@hku.hk-
dc.identifier.emailChin, WY: chinwy@hku.hk-
dc.identifier.emailLam, CLK: clklam@hku.hk-
dc.identifier.authorityFung, SCC=rp01330-
dc.identifier.authorityWong, CKH=rp01931-
dc.identifier.authorityChin, WY=rp00290-
dc.identifier.authorityLam, CLK=rp00350-
dc.identifier.doi10.1016/j.jacc.2015.11.020-
dc.identifier.pmid26821636-
dc.identifier.scopuseid_2-s2.0-84959419024-
dc.identifier.hkuros256898-
dc.identifier.volume67-
dc.identifier.issue4-
dc.identifier.spage456-
dc.identifier.epage458-
dc.identifier.isiWOS:000368615600016-

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