File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Conference Paper: alns - A Searchable and filterable sequence alignment format

Titlealns - A Searchable and filterable sequence alignment format
Authors
Issue Date2010
Citation
The 2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2010), Hong Kong, China, 18-21 December 2010. In Conference Proceedings, 2010, p. 105-108 How to Cite?
AbstractNucleotides and amino acids are basic building units of RNA, DNA and protein. Although intensive studies on understanding how the change of these building blocks affect the phenotypes of these biopolymers are ever increasing, many popular alignment formats are generated by pairwise comparision tools such as the Basic Local Alignment Search Tool (BLAST). These alignments are user friendly to researchers but are not convenient for searching, filtering and storage, in particular when there are thousands of alignments generated from highly conserved sequences.. Here, we introduce a new alignment format, alns, to facilitate rapid and convenient association of genetic changes and similarity to other sources of information such as phenotypes, disease state, time, geography and taxonomy via simple spreadsheet functions. The format shall assist biologists from wide disciplines in knowledge discovery. ©2010 IEEE.
Persistent Identifierhttp://hdl.handle.net/10722/222108
ISBN

 

DC FieldValueLanguage
dc.contributor.authorLeung, Ross K K-
dc.contributor.authorTsui, Stephen K W-
dc.date.accessioned2015-12-21T06:47:53Z-
dc.date.available2015-12-21T06:47:53Z-
dc.date.issued2010-
dc.identifier.citationThe 2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM 2010), Hong Kong, China, 18-21 December 2010. In Conference Proceedings, 2010, p. 105-108-
dc.identifier.isbn978-142448307-5-
dc.identifier.urihttp://hdl.handle.net/10722/222108-
dc.description.abstractNucleotides and amino acids are basic building units of RNA, DNA and protein. Although intensive studies on understanding how the change of these building blocks affect the phenotypes of these biopolymers are ever increasing, many popular alignment formats are generated by pairwise comparision tools such as the Basic Local Alignment Search Tool (BLAST). These alignments are user friendly to researchers but are not convenient for searching, filtering and storage, in particular when there are thousands of alignments generated from highly conserved sequences.. Here, we introduce a new alignment format, alns, to facilitate rapid and convenient association of genetic changes and similarity to other sources of information such as phenotypes, disease state, time, geography and taxonomy via simple spreadsheet functions. The format shall assist biologists from wide disciplines in knowledge discovery. ©2010 IEEE.-
dc.languageeng-
dc.relation.ispartofIEEE International Conference on Bioinformatics and Biomedicine, BIBM 2010 Proceedings-
dc.titlealns - A Searchable and filterable sequence alignment format-
dc.typeConference_Paper-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1109/BIBM.2010.5706546-
dc.identifier.scopuseid_2-s2.0-79952387201-
dc.identifier.spage105-
dc.identifier.epage108-
dc.customcontrol.immutablesml 160506 - amended-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats