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Article: Different outcomes of never-treated and treated patients with schizophrenia: 14-year follow-up study in rural China

TitleDifferent outcomes of never-treated and treated patients with schizophrenia: 14-year follow-up study in rural China
Authors
Issue Date2015
PublisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/
Citation
British Journal of Psychiatry, 2015, v. 207 n. 6, p. 495-500 How to Cite?
AbstractBackgroundThe long-term outcome of never-treated patients with schizophrenia is unclear.AimsTo compare the 14-year outcomes of never-treated and treated patients with schizophrenia and to establish predictors for never being treated.MethodAll participants with schizophrenia (n = 510) in Xinjin, Chengdu, China were identified in an epidemiological investigation of 123 572 people and followed up from 1994 to 2008.ResultsThe results showed that there were 30.6%, 25.0% and 20.4% of patients who received no antipsychotic medication in 1994, 2004 and 2008 respectively. Compared with treated patients, those who were never treated in 2008 were significantly older, had significantly fewer family members, had higher rates of homelessness, death from other causes, being unmarried, living alone, being without a caregiver and poor family attitudes. Partial and complete remission in treated patients (57.3%) was significantly higher than that in the never-treated group (29.8%). Predictors of being in the never-treated group in 2008 encompassed baseline never-treated status, being without a caregiver and poor mental health status in 1994.ConclusionsMany patients with schizophrenia still do not receive antipsychotic medication in rural areas of China. The 14-year follow-up showed that outcomes for the untreated group were worse. Community-based mental healthcare, health insurance and family intervention are crucial for earlier diagnosis, treatment and rehabilitation in the community.
Persistent Identifierhttp://hdl.handle.net/10722/222010
ISSN
2015 Impact Factor: 7.06
2015 SCImago Journal Rankings: 2.674
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorRan, M-
dc.contributor.authorWENG, X-
dc.contributor.authorChan, CLW-
dc.contributor.authorChen, EYH-
dc.contributor.authorTang, CP-
dc.contributor.authorLin, FR-
dc.contributor.authorMao, WJ-
dc.contributor.authorHu, SH-
dc.contributor.authorHuang, YQ-
dc.contributor.authorXiang, MZ-
dc.date.accessioned2015-12-21T05:52:15Z-
dc.date.available2015-12-21T05:52:15Z-
dc.date.issued2015-
dc.identifier.citationBritish Journal of Psychiatry, 2015, v. 207 n. 6, p. 495-500-
dc.identifier.issn0007-1250-
dc.identifier.urihttp://hdl.handle.net/10722/222010-
dc.description.abstractBackgroundThe long-term outcome of never-treated patients with schizophrenia is unclear.AimsTo compare the 14-year outcomes of never-treated and treated patients with schizophrenia and to establish predictors for never being treated.MethodAll participants with schizophrenia (n = 510) in Xinjin, Chengdu, China were identified in an epidemiological investigation of 123 572 people and followed up from 1994 to 2008.ResultsThe results showed that there were 30.6%, 25.0% and 20.4% of patients who received no antipsychotic medication in 1994, 2004 and 2008 respectively. Compared with treated patients, those who were never treated in 2008 were significantly older, had significantly fewer family members, had higher rates of homelessness, death from other causes, being unmarried, living alone, being without a caregiver and poor family attitudes. Partial and complete remission in treated patients (57.3%) was significantly higher than that in the never-treated group (29.8%). Predictors of being in the never-treated group in 2008 encompassed baseline never-treated status, being without a caregiver and poor mental health status in 1994.ConclusionsMany patients with schizophrenia still do not receive antipsychotic medication in rural areas of China. The 14-year follow-up showed that outcomes for the untreated group were worse. Community-based mental healthcare, health insurance and family intervention are crucial for earlier diagnosis, treatment and rehabilitation in the community.-
dc.languageeng-
dc.publisherRoyal College of Psychiatrists. The Journal's web site is located at http://bjp.rcpsych.org/-
dc.relation.ispartofBritish Journal of Psychiatry-
dc.rightsThis is an author-produced electronic version of an article accepted for publication in the British Journal of Psychiatry. The definitive publisher-authenticated version is available online at http://bjp.rcpsych.org-
dc.titleDifferent outcomes of never-treated and treated patients with schizophrenia: 14-year follow-up study in rural China-
dc.typeArticle-
dc.identifier.emailRan, M: msran@hku.hk-
dc.identifier.emailChan, CLW: cecichan@hku.hk-
dc.identifier.emailChen, EYH: eyhchen@hku.hk-
dc.identifier.authorityRan, M=rp01788-
dc.identifier.authorityChan, CLW=rp00579-
dc.identifier.authorityChen, EYH=rp00392-
dc.identifier.doi10.1192/bjp.bp.114.157685-
dc.identifier.pmid26382951-
dc.identifier.pmcidPMC4664855-
dc.identifier.hkuros256398-
dc.identifier.volume207-
dc.identifier.issue6-
dc.identifier.spage495-
dc.identifier.epage500-
dc.publisher.placeUnited Kingdom-

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