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Article: The BEHAVE-AD Assessment System: A Perspective, A Commentary on New Findings, and A Historical Review

TitleThe BEHAVE-AD Assessment System: A Perspective, A Commentary on New Findings, and A Historical Review
Authors
KeywordsDementia
Alzheimer’s disease
Behavioral and psychological symptoms of dementia

Psychiatric status rating scales
Assessments
Pharmacotherapy
Management
Antipsychotics
Anxiolytics
Patient outcome assessment

Issue Date2014
PublisherS Karger AG. The Journal's web site is located at http://www.karger.com/DEM
Citation
Dementia and Geriatric Cognitive Disorders, 2014, v. 38, p. 89-146 How to Cite?
AbstractBackground: Behavioral and psychological symptoms of dementia (BPSD) and associated disturbances in Alzheimer's disease (AD) are a source of distress and burden for spouses, professional caregivers, and others with responsibilities for the care of individuals with AD. BPSD with behavioral disturbances are also associated with more rapid institutionalization and increased morbidity and mortality for persons with AD. Objectives: In this review and commentary, we discuss the history of the development of BPSD and behavioral disturbance assessments, which are distinct from those evaluating cognitive and functional symptoms of AD. In particular, we review the informant-based Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD), the related, potentially more sensitive, BEHAVE-AD Frequency-Weighted Severity Scale (BEHAVE-AD-FW), and the direct subject evaluation-based Empirical BEHAVE-AD Rating Scale (E-BEHAVE-AD). The kinds of medications that alleviate behavioral symptoms on these measures as well as the problems and possibilities for further advances with these medications are discussed. Finally, the importance of distinguishing BPSD and behavioral disturbance remediation in AD from the treatment of cognitive decline and other aspects of AD is emphasized in the context of appropriate assessment methodology. The objective of this paper is to provide a framework for further advances in the treatment of BPSD and associated behavioral disturbances in AD and, consequently, a framework for continuing improvements in the lives of individuals with AD and those who share the burden of the disease with the AD person. © 2014 S. Karger AG, Basel
Persistent Identifierhttp://hdl.handle.net/10722/221662
ISSN
2015 Impact Factor: 3.408
2015 SCImago Journal Rankings: 1.194
PubMed Central ID
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorReisberg, B-
dc.contributor.authorMonteiro, I-
dc.contributor.authorTorossian, C-
dc.contributor.authorAuer, S-
dc.contributor.authorShulman, MB-
dc.contributor.authorGhimire, S-
dc.contributor.authorBoksay, I-
dc.contributor.authorGuillo BenArous, F-
dc.contributor.authorOsorio, R-
dc.contributor.authorVengassery, A-
dc.contributor.authorImran, S-
dc.contributor.authorShaker, H-
dc.contributor.authorNoor, S-
dc.contributor.authorNaqvi, S-
dc.contributor.authorKenowsky, S-
dc.contributor.authorXu, J-
dc.date.accessioned2015-12-04T15:28:57Z-
dc.date.available2015-12-04T15:28:57Z-
dc.date.issued2014-
dc.identifier.citationDementia and Geriatric Cognitive Disorders, 2014, v. 38, p. 89-146-
dc.identifier.issn1420-8008-
dc.identifier.urihttp://hdl.handle.net/10722/221662-
dc.description.abstractBackground: Behavioral and psychological symptoms of dementia (BPSD) and associated disturbances in Alzheimer's disease (AD) are a source of distress and burden for spouses, professional caregivers, and others with responsibilities for the care of individuals with AD. BPSD with behavioral disturbances are also associated with more rapid institutionalization and increased morbidity and mortality for persons with AD. Objectives: In this review and commentary, we discuss the history of the development of BPSD and behavioral disturbance assessments, which are distinct from those evaluating cognitive and functional symptoms of AD. In particular, we review the informant-based Behavioral Pathology in Alzheimer's Disease Rating Scale (BEHAVE-AD), the related, potentially more sensitive, BEHAVE-AD Frequency-Weighted Severity Scale (BEHAVE-AD-FW), and the direct subject evaluation-based Empirical BEHAVE-AD Rating Scale (E-BEHAVE-AD). The kinds of medications that alleviate behavioral symptoms on these measures as well as the problems and possibilities for further advances with these medications are discussed. Finally, the importance of distinguishing BPSD and behavioral disturbance remediation in AD from the treatment of cognitive decline and other aspects of AD is emphasized in the context of appropriate assessment methodology. The objective of this paper is to provide a framework for further advances in the treatment of BPSD and associated behavioral disturbances in AD and, consequently, a framework for continuing improvements in the lives of individuals with AD and those who share the burden of the disease with the AD person. © 2014 S. Karger AG, Basel-
dc.languageeng-
dc.publisherS Karger AG. The Journal's web site is located at http://www.karger.com/DEM-
dc.relation.ispartofDementia and Geriatric Cognitive Disorders-
dc.subjectDementia-
dc.subjectAlzheimer’s disease-
dc.subjectBehavioral and psychological symptoms of dementia-
dc.subject
Psychiatric status rating scales-
dc.subjectAssessments-
dc.subjectPharmacotherapy-
dc.subjectManagement-
dc.subjectAntipsychotics-
dc.subjectAnxiolytics-
dc.subjectPatient outcome assessment
-
dc.titleThe BEHAVE-AD Assessment System: A Perspective, A Commentary on New Findings, and A Historical Review-
dc.typeArticle-
dc.identifier.emailXu, J: xujf@hku.hk-
dc.identifier.authorityXu, J=rp02086-
dc.identifier.doi10.1159/000357839-
dc.identifier.pmid24714384-
dc.identifier.pmcidPMC4216810-
dc.identifier.scopuseid_2-s2.0-84897361348-
dc.identifier.volume38-
dc.identifier.spage89-
dc.identifier.epage146-
dc.identifier.isiWOS:000339893700010-

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