File Download
  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Can the colour of per-rectal bleeding estimate the risk of lower gastrointestinal bleeding caused by malignant lesion?

TitleCan the colour of per-rectal bleeding estimate the risk of lower gastrointestinal bleeding caused by malignant lesion?
Authors
Issue Date2016
PublisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00384/index.htm
Citation
International Journal of Colorectal Disease, 2016, v. 31 n. 2, p. 335-342 How to Cite?
AbstractPURPOSE: To estimate the risk of lower gastrointestinal bleeding (LGIB) caused by malignant lesion in patients presenting with per-rectal bleeding (PRB), by using visual aid as an objective measurement of PRB colour. METHODS: This was a prospective observational study on patients presented with PRB to Family Medicine Specialty Clinic, who undergo flexible sigmoidoscopy (FS) or colonoscopy (CLN) from December 2012 to September 2013. Patients aged 40 years old or above, haemodynamically stable, with normal haemoglobin level were included. Patients with a history of previous colonic surgery, refused to have FS or CLN, with ophthalmologic diseases such as colour blindness were excluded. Parameters including subjective description of PRB colour, number of chosen red colour by patients, source and distance of bleeding from anal verge were recorded for analysis. Receiver operating characteristic (ROC) curve was used to identify the optimal cutoff level of colour for diagnosing colonic lesion. Diagnostic accuracy was assessed by area under the ROC curve (AUC). Accountability of this model was assessed by logistic regression. RESULTS: The dark PRB colour was associated with diagnosis of tumour (p < 0.001) and advanced neoplastic polyp (p < 0.001). The light PRB colour was associated with the diagnosis of piles (p < 0.001). The performance of our model to predict tumour or advanced neoplastic polyps by colour (AUC, 0.798) had a better discriminative power than that to predict colonic lesion alone (AUC, 0.610) by ROC curve analysis. CONCLUSION: Objective measurement of PRB colour accurately estimated the risk of LGIB caused by malignant lesion in patients presenting with PRB.
Persistent Identifierhttp://hdl.handle.net/10722/221544
ISSN
2015 Impact Factor: 2.383
2015 SCImago Journal Rankings: 1.102

 

DC FieldValueLanguage
dc.contributor.authorLai, PY-
dc.contributor.authorChan, KW-
dc.contributor.authorWong, CKH-
dc.contributor.authorMeng, WCS-
dc.contributor.authorLuk, W-
dc.date.accessioned2015-11-30T03:34:31Z-
dc.date.available2015-11-30T03:34:31Z-
dc.date.issued2016-
dc.identifier.citationInternational Journal of Colorectal Disease, 2016, v. 31 n. 2, p. 335-342-
dc.identifier.issn0179-1958-
dc.identifier.urihttp://hdl.handle.net/10722/221544-
dc.description.abstractPURPOSE: To estimate the risk of lower gastrointestinal bleeding (LGIB) caused by malignant lesion in patients presenting with per-rectal bleeding (PRB), by using visual aid as an objective measurement of PRB colour. METHODS: This was a prospective observational study on patients presented with PRB to Family Medicine Specialty Clinic, who undergo flexible sigmoidoscopy (FS) or colonoscopy (CLN) from December 2012 to September 2013. Patients aged 40 years old or above, haemodynamically stable, with normal haemoglobin level were included. Patients with a history of previous colonic surgery, refused to have FS or CLN, with ophthalmologic diseases such as colour blindness were excluded. Parameters including subjective description of PRB colour, number of chosen red colour by patients, source and distance of bleeding from anal verge were recorded for analysis. Receiver operating characteristic (ROC) curve was used to identify the optimal cutoff level of colour for diagnosing colonic lesion. Diagnostic accuracy was assessed by area under the ROC curve (AUC). Accountability of this model was assessed by logistic regression. RESULTS: The dark PRB colour was associated with diagnosis of tumour (p < 0.001) and advanced neoplastic polyp (p < 0.001). The light PRB colour was associated with the diagnosis of piles (p < 0.001). The performance of our model to predict tumour or advanced neoplastic polyps by colour (AUC, 0.798) had a better discriminative power than that to predict colonic lesion alone (AUC, 0.610) by ROC curve analysis. CONCLUSION: Objective measurement of PRB colour accurately estimated the risk of LGIB caused by malignant lesion in patients presenting with PRB.-
dc.languageeng-
dc.publisherSpringer Verlag. The Journal's web site is located at http://link.springer.de/link/service/journals/00384/index.htm-
dc.relation.ispartofInternational Journal of Colorectal Disease-
dc.rightsThe final publication is available at Springer via http://dx.doi.org/10.1007/s00384-015-2414-4-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleCan the colour of per-rectal bleeding estimate the risk of lower gastrointestinal bleeding caused by malignant lesion?-
dc.typeArticle-
dc.identifier.emailWong, CKH: carlosho@hku.hk-
dc.identifier.authorityWong, CKH=rp01931-
dc.description.naturepostprint-
dc.identifier.doi10.1007/s00384-015-2414-4-
dc.identifier.pmid26519152-
dc.identifier.hkuros256211-
dc.identifier.volume31-
dc.identifier.issue2-
dc.identifier.spage335-
dc.identifier.epage342-
dc.publisher.placeGermany-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats