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- Scopus: eid_2-s2.0-84908409804
- PMID: 25267256
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Article: Retrospective study of metachronous lung metastases from primary hepatocellular carcinoma
Title | Retrospective study of metachronous lung metastases from primary hepatocellular carcinoma |
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Authors | |
Keywords | Outcome Segmentectomy Wedge resection Liver Lobectomy |
Issue Date | 2014 |
Citation | ANZ Journal of Surgery, 2014, v. 86 n. 4, p. 289-293 How to Cite? |
Abstract | © 2014 Royal Australasian College of Surgeons. Background: This study investigates whether there has been any survival improvement for hepatocellular carcinoma patients with resectable and unresectable lung metastases over time. Methods: The data of 280 hepatocellular carcinoma patients who developed metachronous lung metastases after hepatectomy with curative intent were analysed. Overall survival was compared in patients with resectable and unresectable lung metastases and in different periods (Era I: 1989-1995, Era II: 1996-2010). Results: The median overall survival of patients with unresectable and resectable diseases was 7.46 and 40.36 months, respectively (P < 0.0001). In Era I, the median overall survival of patients with unresectable and resectable diseases was 5.59 and 43.15 months, respectively (P < 0.0001). The corresponding figures in Era II were 8.38 and 32.90 months (P < 0.0001). The overall survival of patients with resectable disease did not differ significantly in the two eras but there was a significant improvement in survival of patients with unresectable disease in Era II. Their 1-year, 3-year and 5-year survival rates in Era I versus Era II were 11.1% versus 38.4%, 5.6% versus 9.1% and 2.8% versus 3.5%, respectively (P = 0.041). The corresponding figures for their counterparts in the resectable group were 90% versus 85.8%, 80% versus 45.9% and 40% versus 29.5%, respectively (P = 0.443). Conclusions: Patients with resectable lung metastases had better overall survival than those with unresectable lung metastases. Notably, patients with unresectable lung metastases had significant improvement in survival over the years. |
Persistent Identifier | http://hdl.handle.net/10722/221372 |
ISSN | 2023 Impact Factor: 1.5 2023 SCImago Journal Rankings: 0.453 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chok, KSH | - |
dc.contributor.author | Yau, TCC | - |
dc.contributor.author | Cheung, TT | - |
dc.contributor.author | Poon, RTP | - |
dc.contributor.author | Lo, CM | - |
dc.date.accessioned | 2015-11-18T06:09:08Z | - |
dc.date.available | 2015-11-18T06:09:08Z | - |
dc.date.issued | 2014 | - |
dc.identifier.citation | ANZ Journal of Surgery, 2014, v. 86 n. 4, p. 289-293 | - |
dc.identifier.issn | 1445-1433 | - |
dc.identifier.uri | http://hdl.handle.net/10722/221372 | - |
dc.description.abstract | © 2014 Royal Australasian College of Surgeons. Background: This study investigates whether there has been any survival improvement for hepatocellular carcinoma patients with resectable and unresectable lung metastases over time. Methods: The data of 280 hepatocellular carcinoma patients who developed metachronous lung metastases after hepatectomy with curative intent were analysed. Overall survival was compared in patients with resectable and unresectable lung metastases and in different periods (Era I: 1989-1995, Era II: 1996-2010). Results: The median overall survival of patients with unresectable and resectable diseases was 7.46 and 40.36 months, respectively (P < 0.0001). In Era I, the median overall survival of patients with unresectable and resectable diseases was 5.59 and 43.15 months, respectively (P < 0.0001). The corresponding figures in Era II were 8.38 and 32.90 months (P < 0.0001). The overall survival of patients with resectable disease did not differ significantly in the two eras but there was a significant improvement in survival of patients with unresectable disease in Era II. Their 1-year, 3-year and 5-year survival rates in Era I versus Era II were 11.1% versus 38.4%, 5.6% versus 9.1% and 2.8% versus 3.5%, respectively (P = 0.041). The corresponding figures for their counterparts in the resectable group were 90% versus 85.8%, 80% versus 45.9% and 40% versus 29.5%, respectively (P = 0.443). Conclusions: Patients with resectable lung metastases had better overall survival than those with unresectable lung metastases. Notably, patients with unresectable lung metastases had significant improvement in survival over the years. | - |
dc.language | eng | - |
dc.relation.ispartof | ANZ Journal of Surgery | - |
dc.subject | Outcome | - |
dc.subject | Segmentectomy | - |
dc.subject | Wedge resection | - |
dc.subject | Liver | - |
dc.subject | Lobectomy | - |
dc.title | Retrospective study of metachronous lung metastases from primary hepatocellular carcinoma | - |
dc.type | Article | - |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1111/ans.12859 | - |
dc.identifier.pmid | 25267256 | - |
dc.identifier.scopus | eid_2-s2.0-84908409804 | - |
dc.identifier.hkuros | 241977 | - |
dc.identifier.hkuros | 239995 | - |
dc.identifier.hkuros | 308989 | - |
dc.identifier.volume | 86 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 289 | - |
dc.identifier.epage | 293 | - |
dc.identifier.eissn | 1445-2197 | - |
dc.identifier.isi | WOS:000373799800018 | - |
dc.identifier.issnl | 1445-1433 | - |