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Article: Photoaffinity Labeling of Small-Molecule-Binding Proteins by DNA-Templated Chemistry

TitlePhotoaffinity Labeling of Small-Molecule-Binding Proteins by DNA-Templated Chemistry
Authors
Issue Date2013
PublisherWiley - V C H Verlag GmbH & Co. KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/journal/26737/home
Citation
Angewandte Chemie (International Edition), 2013, v. 52 n. 36, p. 9544-9549 How to Cite?
AbstractDNA-templated affinity labeling: Accurate characterization of small-molecule (SM)-protein interactions is one of the most important but also very challenging tasks in chemical biology and drug discovery. A novel method named DNA-programmed photoaffinity labeling is reported. The introduction of DNA encoding and template effect enable multiplexed protein labeling by multiple probes. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Persistent Identifierhttp://hdl.handle.net/10722/221120
ISSN
2015 Impact Factor: 11.709
2015 SCImago Journal Rankings: 6.229
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, G-
dc.contributor.authorLiu, Ying-
dc.contributor.authorLiu, Yu-
dc.contributor.authorChen, L-
dc.contributor.authorWu, S-
dc.contributor.authorLiu, Yang-
dc.contributor.authorLi, X-
dc.date.accessioned2015-10-27T09:18:42Z-
dc.date.available2015-10-27T09:18:42Z-
dc.date.issued2013-
dc.identifier.citationAngewandte Chemie (International Edition), 2013, v. 52 n. 36, p. 9544-9549-
dc.identifier.issn1433-7851-
dc.identifier.urihttp://hdl.handle.net/10722/221120-
dc.description.abstractDNA-templated affinity labeling: Accurate characterization of small-molecule (SM)-protein interactions is one of the most important but also very challenging tasks in chemical biology and drug discovery. A novel method named DNA-programmed photoaffinity labeling is reported. The introduction of DNA encoding and template effect enable multiplexed protein labeling by multiple probes. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.-
dc.languageeng-
dc.publisherWiley - V C H Verlag GmbH & Co. KGaA. The Journal's web site is located at http://www3.interscience.wiley.com/journal/26737/home-
dc.relation.ispartofAngewandte Chemie (International Edition)-
dc.titlePhotoaffinity Labeling of Small-Molecule-Binding Proteins by DNA-Templated Chemistry-
dc.typeArticle-
dc.identifier.emailLi, X: xiaoyuli@hku.hk-
dc.identifier.authorityLi, X=rp02080-
dc.identifier.doi10.1002/anie.201302161-
dc.identifier.pmid23776013-
dc.identifier.scopuseid=2-s2.0-84883228365-
dc.identifier.volume52-
dc.identifier.issue36-
dc.identifier.spage9544-
dc.identifier.epage9549-
dc.identifier.isiWOS:000323474600028-
dc.publisher.placeGermany-

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