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Article: Hypergastrinemia In Children With Duodenal Ulcer

TitleHypergastrinemia In Children With Duodenal Ulcer
Authors
Issue Date1988
PublisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurg
Citation
Journal Of Pediatric Surgery, 1988, v. 23 n. 4, p. 331-334 How to Cite?
AbstractSerum Gastrin Concentrations Were Determined In 25 Children With Duodenal Ulcer (Du) And 25 Normal Children. Fasting Values Were Significantly Higher In Du Children (Mean ± Se = 60.4 ± 9.7 Pg/Ml) Than In Controls (Mean ± Se = 38.0 ± 4.2 Pg/Ml; P < .05). Integrated Gastrin Response To Meal Stimulation Was Also Significantly Higher In Du Children (Mean ± Se = 140.5 ± 32.4%) Than In Controls (Mean ± Se = 62.3 ± 12.2%; P < .05). Excessive Gastrin Activity (Greater Than Normal Mean ± 2 Sd), Either Fasting Or Meal-Stimulated, Occurred In 11 Of 17 Normal Acid Secretors And In Two Of Eight Hypersecretors In The Du Group. The Present Findings Suggest That Excessive Gastrin Activity Is A Major Factor In The Pathogenesis Of Childhood Du. Unlike Adult Du, Which Is Associated With Normal Fasting Gastrin Concentrations, Childhood Du Manifests Exaggerated Gastrin Activity Both In The Fasting And Postprandial States.
Persistent Identifierhttp://hdl.handle.net/10722/220818
ISSN
2015 Impact Factor: 1.733
2015 SCImago Journal Rankings: 0.802
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTam, PKHen_US
dc.date.accessioned2015-10-19T04:20:57Z-
dc.date.available2015-10-19T04:20:57Z-
dc.date.issued1988-
dc.identifier.citationJournal Of Pediatric Surgery, 1988, v. 23 n. 4, p. 331-334en_US
dc.identifier.issn0022-3468-
dc.identifier.urihttp://hdl.handle.net/10722/220818-
dc.description.abstractSerum Gastrin Concentrations Were Determined In 25 Children With Duodenal Ulcer (Du) And 25 Normal Children. Fasting Values Were Significantly Higher In Du Children (Mean ± Se = 60.4 ± 9.7 Pg/Ml) Than In Controls (Mean ± Se = 38.0 ± 4.2 Pg/Ml; P < .05). Integrated Gastrin Response To Meal Stimulation Was Also Significantly Higher In Du Children (Mean ± Se = 140.5 ± 32.4%) Than In Controls (Mean ± Se = 62.3 ± 12.2%; P < .05). Excessive Gastrin Activity (Greater Than Normal Mean ± 2 Sd), Either Fasting Or Meal-Stimulated, Occurred In 11 Of 17 Normal Acid Secretors And In Two Of Eight Hypersecretors In The Du Group. The Present Findings Suggest That Excessive Gastrin Activity Is A Major Factor In The Pathogenesis Of Childhood Du. Unlike Adult Du, Which Is Associated With Normal Fasting Gastrin Concentrations, Childhood Du Manifests Exaggerated Gastrin Activity Both In The Fasting And Postprandial States.en_US
dc.languageengen_US
dc.publisherWB Saunders Co. The Journal's web site is located at http://www.elsevier.com/locate/jpedsurgen_US
dc.relation.ispartofJournal Of Pediatric Surgeryen_US
dc.titleHypergastrinemia In Children With Duodenal Ulceren_US
dc.typeArticleen_US
dc.identifier.emailTam, PKH:paultam@hkucc.hku.hk-
dc.identifier.authorityTam, PKH=rp00060-
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid3385585-
dc.identifier.scopuseid_2-s2.0-0023942686-
dc.identifier.volume23-
dc.identifier.issue4-
dc.identifier.spage331-
dc.identifier.epage334-
dc.identifier.isiWOS:A1988M927400008-

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