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Article: Hirschsprung's Disease: A Viral Etiology?

TitleHirschsprung's Disease: A Viral Etiology?
Authors
Issue Date1992
Citation
Pediatric Pathology, 1992, v. 12 n. 6, p. 807-810 How to Cite?
AbstractThis Study Investigates The Hypothesis That Hirschsprung's Disease (Hd), Congenital Rectal Aganglionosis, May Be Etiologically Linked To Antenatal Cytomegalovirus (Cmv) Infection. Bowel Specimens From 72 Hd Patients, 144 Control I Infants (Hirschsprung-Like Symptoms, Normal Histology), And 36 Control Ii Infants (Deaths From Nongastrointestinal Causes) Were Analyzed For Cmv Genomes By Polymerase Chain Reaction. Positive Results Were Obtained In 6 Hd Patients (8.8%) And None Of The Controls. Our Findings Suggest That Antenatal Cmv Infection, A Potentially Preventable Condition, May Be One Of The Etiological Factors In Hd.
Persistent Identifierhttp://hdl.handle.net/10722/220796
ISSN
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorTam, PKHen_US
dc.contributor.authorQuint, WGVen_US
dc.contributor.authorVan Velzen, Den_US
dc.date.accessioned2015-10-19T03:49:59Z-
dc.date.available2015-10-19T03:49:59Z-
dc.date.issued1992-
dc.identifier.citationPediatric Pathology, 1992, v. 12 n. 6, p. 807-810en_US
dc.identifier.issn0277-0938-
dc.identifier.urihttp://hdl.handle.net/10722/220796-
dc.description.abstractThis Study Investigates The Hypothesis That Hirschsprung's Disease (Hd), Congenital Rectal Aganglionosis, May Be Etiologically Linked To Antenatal Cytomegalovirus (Cmv) Infection. Bowel Specimens From 72 Hd Patients, 144 Control I Infants (Hirschsprung-Like Symptoms, Normal Histology), And 36 Control Ii Infants (Deaths From Nongastrointestinal Causes) Were Analyzed For Cmv Genomes By Polymerase Chain Reaction. Positive Results Were Obtained In 6 Hd Patients (8.8%) And None Of The Controls. Our Findings Suggest That Antenatal Cmv Infection, A Potentially Preventable Condition, May Be One Of The Etiological Factors In Hd.en_US
dc.languageengen_US
dc.relation.ispartofPediatric Pathologyen_US
dc.titleHirschsprung's Disease: A Viral Etiology?en_US
dc.typeArticleen_US
dc.identifier.emailTam, PKH:paultam@hkucc.hku.hk-
dc.identifier.authorityTam, PKH=rp00060-
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid1333073-
dc.identifier.scopuseid_2-s2.0-0026442899-
dc.identifier.volume12-
dc.identifier.issue6-
dc.identifier.spage807-
dc.identifier.epage810-
dc.identifier.isiWOS:A1992JY61500004-

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