Colonic stricture and fibrosis associated with high-strength pancreatic enzymes in a child with cystic fibrosis

Abstract

High-strength pancreatic enzymes have recently been implicated as a cause Or colonic strictures in children with cystic fibrosis (CF). We report a 5-year-old boy with CF who had a stricture of the hepatic flexure region with associated narrowing due to submucosal fibrosis of the transverse colon, secondary to high-lipase pancreatin therapy.