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Conference Paper: Liver transplant for biliary atresia is associated with a worse outcome: myth or fact?

TitleLiver transplant for biliary atresia is associated with a worse outcome: myth or fact?
Authors
KeywordsLiver transplant
Biliary atresia
Kasai operation
Issue Date2015
Citation
The 48th Annual Meeting of the Pacific Association of Pediatric Surgeons (PAPS 2015), Jeju Island, Korea, 17-21 May 2015. In Journal of Pediatric Surgery, 2015, v. 50 n. 12, p. 2134-2136 How to Cite?
AbstractBackground: Liver transplant for biliary atresia (BA) has been reported to be associated with worse outcome, but this remains controversial. The objective of this study is to compare the outcomes of BA and non-BA recipients. Methods: Recipients with age <. 18. years were reviewed except cases of retransplantation. Intratransplant and posttransplant complications as well as survivals were evaluated. Results: 119 patients, with median follow-up period 8.5. years, were studied (DDLT = 33; LDLT = 86/M:F = 56:63), and 68% (n = 81) were BA patients. While demographic data were comparable between two groups of recipients, BA patients had a worse pretransplant PELD/MELD score (15.2 vs 4.0, p = 0.021). Transplantation takes a longer time in the BA group (580. min vs 400. min, p = 0.065) with more blood loss (720. ml vs 500. ml, p = 0.072). The incidence of transplant-related complications was 30.3% (36/119) (Table1). There was no significant difference between incidences of vascular complication, but biliary complication was more common in the BA group. Overall, the survivals between the two groups were comparable. Conclusions: Liver transplant is an effective surgical treatment for BA patients. When compared to other indications, results are not inferior. Previous Kasai operation is not necessarily associated with adverse outcomes. © 2015 Elsevier Inc.
Persistent Identifierhttp://hdl.handle.net/10722/220725
ISSN
2015 Impact Factor: 1.733
2015 SCImago Journal Rankings: 0.802

 

DC FieldValueLanguage
dc.contributor.authorChung, HY-
dc.contributor.authorWong, KKY-
dc.contributor.authorChan, SC-
dc.contributor.authorTam, PKH-
dc.date.accessioned2015-10-16T06:50:23Z-
dc.date.available2015-10-16T06:50:23Z-
dc.date.issued2015-
dc.identifier.citationThe 48th Annual Meeting of the Pacific Association of Pediatric Surgeons (PAPS 2015), Jeju Island, Korea, 17-21 May 2015. In Journal of Pediatric Surgery, 2015, v. 50 n. 12, p. 2134-2136-
dc.identifier.issn0022-3468-
dc.identifier.urihttp://hdl.handle.net/10722/220725-
dc.description.abstractBackground: Liver transplant for biliary atresia (BA) has been reported to be associated with worse outcome, but this remains controversial. The objective of this study is to compare the outcomes of BA and non-BA recipients. Methods: Recipients with age <. 18. years were reviewed except cases of retransplantation. Intratransplant and posttransplant complications as well as survivals were evaluated. Results: 119 patients, with median follow-up period 8.5. years, were studied (DDLT = 33; LDLT = 86/M:F = 56:63), and 68% (n = 81) were BA patients. While demographic data were comparable between two groups of recipients, BA patients had a worse pretransplant PELD/MELD score (15.2 vs 4.0, p = 0.021). Transplantation takes a longer time in the BA group (580. min vs 400. min, p = 0.065) with more blood loss (720. ml vs 500. ml, p = 0.072). The incidence of transplant-related complications was 30.3% (36/119) (Table1). There was no significant difference between incidences of vascular complication, but biliary complication was more common in the BA group. Overall, the survivals between the two groups were comparable. Conclusions: Liver transplant is an effective surgical treatment for BA patients. When compared to other indications, results are not inferior. Previous Kasai operation is not necessarily associated with adverse outcomes. © 2015 Elsevier Inc.-
dc.languageeng-
dc.relation.ispartofJournal of Pediatric Surgery-
dc.subjectLiver transplant-
dc.subjectBiliary atresia-
dc.subjectKasai operation-
dc.titleLiver transplant for biliary atresia is associated with a worse outcome: myth or fact?-
dc.typeConference_Paper-
dc.identifier.emailChung, HY: chungphy@hku.hk-
dc.identifier.emailWong, KKY: kkywong@hku.hk-
dc.identifier.emailChan, SC: chanlsc@hkucc.hku.hk-
dc.identifier.emailTam, PKH: paultam@hku.hk-
dc.identifier.authorityChung, HY=rp02002-
dc.identifier.authorityWong, KKY=rp01392-
dc.identifier.authorityChan, SC=rp01568-
dc.identifier.authorityTam, PKH=rp00060-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.jpedsurg.2015.08.042-
dc.identifier.pmid26392059-
dc.identifier.scopuseid_2-s2.0-84942024416-
dc.identifier.hkuros246082-
dc.identifier.hkuros256837-
dc.identifier.volume50-
dc.identifier.issue12-
dc.identifier.spage2134-
dc.identifier.epage2136-
dc.identifier.eissn1531-5037-
dc.customcontrol.immutablesml 160704 merged-

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