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Article: Nasopharyngeal carcinoma: presenting symptoms and duration before diagnosis

TitleNasopharyngeal carcinoma: presenting symptoms and duration before diagnosis
Authors
Issue Date1997
Citation
Hong Kong medical journal, 1997, v. 3 n. 4, p. 355-361 How to Cite?
AbstractThis is a retrospective analysis of 4768 patients with undifferentiated or non-keratinising carcinoma of the nasopharynx who were treated during 1 January 1976 to 31 December 1985. The mean duration of symptoms before diagnosis was 8 months (range, 1-36 months for 95% of patients). A significant association between the duration of symptoms and the presenting stage was observed (P<0.001); 58% and 39% of stage I and stage V patients, respectively, reported as having had symptoms for less than 6 months. Of the later presenters (those having had symptoms for 6 months or longer), 89% were given a full course of radical megavoltage radiotherapy, but 6% were too advanced for any irradiation attempt. Consequently, the 10-year actuarial disease-specific survival was significantly higher among the early presenters: 48% versus 42% (P<0.001). The importance of early detection is emphasised.
Persistent Identifierhttp://hdl.handle.net/10722/220024
ISSN
2015 Impact Factor: 0.887
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorLee, WMA-
dc.contributor.authorFoo, W-
dc.contributor.authorLaw, SC-
dc.contributor.authorPoon, YF-
dc.contributor.authorSze, WM-
dc.contributor.authorO, SK-
dc.contributor.authorTung, SY-
dc.contributor.authorLau, WH-
dc.date.accessioned2015-10-16T06:16:27Z-
dc.date.available2015-10-16T06:16:27Z-
dc.date.issued1997-
dc.identifier.citationHong Kong medical journal, 1997, v. 3 n. 4, p. 355-361-
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/220024-
dc.description.abstractThis is a retrospective analysis of 4768 patients with undifferentiated or non-keratinising carcinoma of the nasopharynx who were treated during 1 January 1976 to 31 December 1985. The mean duration of symptoms before diagnosis was 8 months (range, 1-36 months for 95% of patients). A significant association between the duration of symptoms and the presenting stage was observed (P<0.001); 58% and 39% of stage I and stage V patients, respectively, reported as having had symptoms for less than 6 months. Of the later presenters (those having had symptoms for 6 months or longer), 89% were given a full course of radical megavoltage radiotherapy, but 6% were too advanced for any irradiation attempt. Consequently, the 10-year actuarial disease-specific survival was significantly higher among the early presenters: 48% versus 42% (P<0.001). The importance of early detection is emphasised.-
dc.languageeng-
dc.relation.ispartofHong Kong medical journal-
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleNasopharyngeal carcinoma: presenting symptoms and duration before diagnosis-
dc.typeArticle-
dc.identifier.emailLee, WMA: awmlee@hkucc.hku.hk-
dc.identifier.authorityLee, WMA=rp02056-
dc.description.naturepublished_or_final_version-
dc.identifier.pmid11847385-
dc.identifier.hkuros266626-
dc.identifier.volume3-
dc.identifier.issue4-
dc.identifier.spage355-
dc.identifier.epage361-

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