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Article: Update in management of hepatocellular carcinoma in Eastern population

TitleUpdate in management of hepatocellular carcinoma in Eastern population
Authors
Issue Date2015
PublisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1948-5182/index.htm
Citation
World Journal of Hepatology, 2015, v. 7 n. 11, p. 1562-1571 How to Cite?
AbstractHepatocellular carcinoma (HCC) is one of the commonest malignant tumours in the East. Although the management of HCC in the West is mainly based on the Barcelona Clinic for Liver Cancer staging, it is considered too conservative by Asian countries where the number of HCC patients is huge. Scientific and clinical advances were made in aspects of diagnosis, staging, and treatment of HCC. HCC is well known to be associated with cirrhosis and the treatment of HCC must take into account the presence and stage of chronic liver disease. The major treatment modalities of HCC include: (1) surgical resection; (2) liver transplantation; (3) local ablation therapy; (4) transarterial locoregional treatment; and (5) systemic treatment. Among these, resection, liver transplantation and ablation therapy for small HCC are considered as curative treatment. Portal vein embolisation and the associating liver partition with portal vein ligation for staged hepatectomy may reduce dropout in patients with marginally resectable disease but the midterm and long-term results are still to be confirmed. Patient selection for the best treatment modality is the key to success of treatment of HCC. The purpose of current review is to provide a description of the current advances in diagnosis, staging, preoperative liver function assessment and treatment options for patients with HCC in the east. © 2015 Baishideng Publishing Group Inc.
Persistent Identifierhttp://hdl.handle.net/10722/217271
ISSN
2015 SCImago Journal Rankings: 0.858
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorChu, KK-
dc.contributor.authorCheung, TT-
dc.date.accessioned2015-09-18T05:54:35Z-
dc.date.available2015-09-18T05:54:35Z-
dc.date.issued2015-
dc.identifier.citationWorld Journal of Hepatology, 2015, v. 7 n. 11, p. 1562-1571-
dc.identifier.issn1948-5182-
dc.identifier.urihttp://hdl.handle.net/10722/217271-
dc.description.abstractHepatocellular carcinoma (HCC) is one of the commonest malignant tumours in the East. Although the management of HCC in the West is mainly based on the Barcelona Clinic for Liver Cancer staging, it is considered too conservative by Asian countries where the number of HCC patients is huge. Scientific and clinical advances were made in aspects of diagnosis, staging, and treatment of HCC. HCC is well known to be associated with cirrhosis and the treatment of HCC must take into account the presence and stage of chronic liver disease. The major treatment modalities of HCC include: (1) surgical resection; (2) liver transplantation; (3) local ablation therapy; (4) transarterial locoregional treatment; and (5) systemic treatment. Among these, resection, liver transplantation and ablation therapy for small HCC are considered as curative treatment. Portal vein embolisation and the associating liver partition with portal vein ligation for staged hepatectomy may reduce dropout in patients with marginally resectable disease but the midterm and long-term results are still to be confirmed. Patient selection for the best treatment modality is the key to success of treatment of HCC. The purpose of current review is to provide a description of the current advances in diagnosis, staging, preoperative liver function assessment and treatment options for patients with HCC in the east. © 2015 Baishideng Publishing Group Inc.-
dc.languageeng-
dc.publisherBaishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1948-5182/index.htm-
dc.relation.ispartofWorld Journal of Hepatology-
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License-
dc.titleUpdate in management of hepatocellular carcinoma in Eastern population-
dc.typeArticle-
dc.identifier.emailCheung, TT: cheung68@hku.hk-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.4254/wjh.v7.i11.1562-
dc.identifier.pmid26085915-
dc.identifier.pmcidPMC4462694-
dc.identifier.scopuseid_2-s2.0-84930852131-
dc.identifier.hkuros254808-
dc.identifier.volume7-
dc.identifier.issue11-
dc.identifier.spage1562-
dc.identifier.epage1571-
dc.publisher.placeUnited States-

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