File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Multifunctional in situ photopolymerized semi-interpenetrating network system is an effective donor site dressing: A cross comparison study in a swine model

TitleMultifunctional in situ photopolymerized semi-interpenetrating network system is an effective donor site dressing: A cross comparison study in a swine model
Authors
Issue Date2009
Citation
Journal of Burn Care and Research, 2009, v. 30, n. 1, p. 37-45 How to Cite?
AbstractEffective dressings for donor sites or other partial thickness wounds must promote removal of nonviable or necrotic tissue, eradication and prevention of microbial infiltrate, exudate absorbance, and regrowth of healthy epidermis and dermis. There are many commonly used products that facilitate these processes. Established properties of an in situ photopolymerizable semi- interpenetrating network (sIPN) suggest that it is also a viable treatment option. The widely varying material properties suggest that these dressing treatments may elicit different healing responses via different cellular mechanisms. In this study, we sought to resolve the differences in healing between Acticoat™, sIPN, nonadherent dressing with Tisseel™, and Xeroform™ dressing treatments in a porcine partial thickness wound model. Donor site wounds were produced on pigs at two cut depths and dressed with Acticoat™, sIPN, nonadherent dressing with Tisseel™, and Xeroform™ with alternatively placed autografts to provide a control area between each test site. Figs were euthanized at 4, 7, 14, and 42 days for macroscopic examination and biopsy collection. Biopsies were analyzed histologically by two blinded observers for cellular densities and regional thicknesses within the tissue. sIPN- and Xeroform™-treated wounds were healed by 7 days, and Acticoat™- and nonadherent dressing with Tisseel™-treated wounds were healed by 14 days. Inflammatory responses were between comparable treatment type across all time periods. Dermal granulation features increased with time but were not significantly different. All dressing treatments elicited wound healing without outstanding toxicity or pathology indicating that sIPN is a comparable and viable treatment for partial thickness wounds. Copyright © 2009 by the American Burn Association.
Persistent Identifierhttp://hdl.handle.net/10722/216196
ISSN
2015 Impact Factor: 1.37
2015 SCImago Journal Rankings: 0.713

 

DC FieldValueLanguage
dc.contributor.authorKleinbeck, Kyle R.-
dc.contributor.authorFaucher, Lee-
dc.contributor.authorKao, Weiyuan John-
dc.date.accessioned2015-08-25T10:22:21Z-
dc.date.available2015-08-25T10:22:21Z-
dc.date.issued2009-
dc.identifier.citationJournal of Burn Care and Research, 2009, v. 30, n. 1, p. 37-45-
dc.identifier.issn1559-047X-
dc.identifier.urihttp://hdl.handle.net/10722/216196-
dc.description.abstractEffective dressings for donor sites or other partial thickness wounds must promote removal of nonviable or necrotic tissue, eradication and prevention of microbial infiltrate, exudate absorbance, and regrowth of healthy epidermis and dermis. There are many commonly used products that facilitate these processes. Established properties of an in situ photopolymerizable semi- interpenetrating network (sIPN) suggest that it is also a viable treatment option. The widely varying material properties suggest that these dressing treatments may elicit different healing responses via different cellular mechanisms. In this study, we sought to resolve the differences in healing between Acticoat™, sIPN, nonadherent dressing with Tisseel™, and Xeroform™ dressing treatments in a porcine partial thickness wound model. Donor site wounds were produced on pigs at two cut depths and dressed with Acticoat™, sIPN, nonadherent dressing with Tisseel™, and Xeroform™ with alternatively placed autografts to provide a control area between each test site. Figs were euthanized at 4, 7, 14, and 42 days for macroscopic examination and biopsy collection. Biopsies were analyzed histologically by two blinded observers for cellular densities and regional thicknesses within the tissue. sIPN- and Xeroform™-treated wounds were healed by 7 days, and Acticoat™- and nonadherent dressing with Tisseel™-treated wounds were healed by 14 days. Inflammatory responses were between comparable treatment type across all time periods. Dermal granulation features increased with time but were not significantly different. All dressing treatments elicited wound healing without outstanding toxicity or pathology indicating that sIPN is a comparable and viable treatment for partial thickness wounds. Copyright © 2009 by the American Burn Association.-
dc.languageeng-
dc.relation.ispartofJournal of Burn Care and Research-
dc.titleMultifunctional in situ photopolymerized semi-interpenetrating network system is an effective donor site dressing: A cross comparison study in a swine model-
dc.typeArticle-
dc.description.natureLink_to_subscribed_fulltext-
dc.identifier.doi10.1097/BCR.0b013e3181921f98-
dc.identifier.pmid19131760-
dc.identifier.scopuseid_2-s2.0-59449090855-
dc.identifier.volume30-
dc.identifier.issue1-
dc.identifier.spage37-
dc.identifier.epage45-
dc.identifier.eissn1559-0488-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats